SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nye'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 1nye OSMOTICALLY
INDUCIBLE PROTEIN C
(Escherichia
coli) 		4 / 6 ALA A 153
ILE A 155
HIS A  76
VAL A 147
 None
 1.14A 3nneG-1nyeA:
undetectable		 3nneG-1nyeA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 1nye OSMOTICALLY
INDUCIBLE PROTEIN C
(Escherichia
coli) 		5 / 8 ALA A 102
ILE A 118
LEU A 120
ALA A  75
ALA A  78
 None
 1.38A 3r9tA-1nyeA:
undetectable		 3r9tA-1nyeA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1nye OSMOTICALLY
INDUCIBLE PROTEIN C
(Escherichia
coli) 		4 / 8 ILE A 129
VAL A 126
TYR A 159
ILE A 138
 None
 0.90A 5mzrE-1nyeA:
undetectable		 5mzrE-1nyeA:
20.30