SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nyo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_E_SVRE510_3 (PHOSPHOLIPASE A2)	1nyo	IMMUNOGENIC PROTEIN MPT70 (Mycobacterium tuberculosis)	4 / 5	VAL A 102 VAL A 103 THR A 147 THR A 99	None	1.25A	3bjwG-1nyoA: undetectable	3bjwG-1nyoA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_H_SVRH511_2 (PHOSPHOLIPASE A2)	1nyo	IMMUNOGENIC PROTEIN MPT70 (Mycobacterium tuberculosis)	4 / 5	VAL A 102 VAL A 103 THR A 147 THR A 99	None	1.30A	3bjwD-1nyoA: undetectable	3bjwD-1nyoA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3THR_A_C2FA1100_0 (GLYCINE N-METHYLTRANSFERASE)	1nyo	IMMUNOGENIC PROTEIN MPT70 (Mycobacterium tuberculosis)	4 / 6	SER A 48 LEU A 98 HIS A 101 THR A 44	None	1.45A	3thrB-1nyoA: undetectable	3thrB-1nyoA: 21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E3H_A_HQEA303_1 (CARBONIC ANHYDRASE 2)	1nyo	IMMUNOGENIC PROTEIN MPT70 (Mycobacterium tuberculosis)	5 / 10	VAL A 126 LEU A 133 VAL A 135 THR A 67 VAL A 140	None	0.96A	4e3hA-1nyoA: undetectable	4e3hA-1nyoA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E3H_A_HQEA303_1 (CARBONIC ANHYDRASE 2)	1nyo	IMMUNOGENIC PROTEIN MPT70 (Mycobacterium tuberculosis)	5 / 10	VAL A 126 LEU A 133 VAL A 135 THR A 151 VAL A 140	None	1.07A	4e3hA-1nyoA: undetectable	4e3hA-1nyoA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_A_SAMA401_0 (PAVINE N-METHYLTRANSFERASE)	1nyo	IMMUNOGENIC PROTEIN MPT70 (Mycobacterium tuberculosis)	5 / 12	GLY A 143 VAL A 126 THR A 125 VAL A 68 ALA A 70	None	1.08A	5kocA-1nyoA: undetectable	5kocA-1nyoA: 17.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJW_E_SVRE510_3","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","1nyo","IMMUNOGENIC PROTEIN MPT70","Mycobacterium tuberculosis",4,"VAL A 102;VAL A 103;THR A 147;THR A  99","None","1.25A","3bjwG-1nyoA:undetectable","3bjwG-1nyoA:17.72"],["3BJW_H_SVRH511_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","1nyo","IMMUNOGENIC PROTEIN MPT70","Mycobacterium tuberculosis",4,"VAL A 102;VAL A 103;THR A 147;THR A  99","None","1.30A","3bjwD-1nyoA:undetectable","3bjwD-1nyoA:17.72"],["3THR_A_C2FA1100_0","GLYCINE N-METHYLTRANSFERASE","1nyo","IMMUNOGENIC PROTEIN MPT70","Mycobacterium tuberculosis",4,"SER A  48;LEU A  98;HIS A 101;THR A  44","None","1.45A","3thrB-1nyoA:undetectable","3thrB-1nyoA:21.09"],["4E3H_A_HQEA303_1","CARBONIC ANHYDRASE 2","1nyo","IMMUNOGENIC PROTEIN MPT70","Mycobacterium tuberculosis",5,"VAL A 126;LEU A 133;VAL A 135;THR A  67;VAL A 140","None","0.96A","4e3hA-1nyoA:undetectable","4e3hA-1nyoA:20.00"],["4E3H_A_HQEA303_1","CARBONIC ANHYDRASE 2","1nyo","IMMUNOGENIC PROTEIN MPT70","Mycobacterium tuberculosis",5,"VAL A 126;LEU A 133;VAL A 135;THR A 151;VAL A 140","None","1.07A","4e3hA-1nyoA:undetectable","4e3hA-1nyoA:20.00"],["5KOC_A_SAMA401_0","PAVINE N-METHYLTRANSFERASE","1nyo","IMMUNOGENIC PROTEIN MPT70","Mycobacterium tuberculosis",5,"GLY A 143;VAL A 126;THR A 125;VAL A  68;ALA A  70","None","1.08A","5kocA-1nyoA:undetectable","5kocA-1nyoA:17.72"]]