SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nzi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 1nzi COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		4 / 4 HIS A  41
ALA A 109
PHE A  39
GLY A 107
 None
 1.39A 1mj2B-1nziA:
undetectable		 1mj2B-1nziA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 1nzi COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		4 / 4 HIS A  41
ALA A 109
PHE A  39
GLY A 107
 None
 1.39A 1mjoB-1nziA:
undetectable		 1mjoB-1nziA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 1nzi COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		4 / 4 HIS A  41
ALA A 109
PHE A  39
GLY A 107
 None
 1.41A 1mjoD-1nziA:
undetectable		 1mjoD-1nziA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1nzi COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		4 / 8 LEU A  42
PHE A  39
PHE A  84
PRO A  79
 None
 1.02A 5m0oC-1nziA:
undetectable		 5m0oC-1nziA:
16.24