SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nzj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		4 / 6 ARG A 107
GLY A 117
ASP A 116
TYR A  99
 None
 1.14A 1kf6M-1nzjA:
0.0
1kf6N-1nzjA:
0.0		 1kf6M-1nzjA:
19.15
1kf6N-1nzjA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		5 / 12 VAL A 267
LEU A 271
LEU A  23
LEU A 247
LEU A  18
 None
 1.14A 1mx1C-1nzjA:
undetectable		 1mx1C-1nzjA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		3 / 3 VAL A 176
ALA A 175
HIS A  82
 None
 0.71A 1q23J-1nzjA:
undetectable		 1q23J-1nzjA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		4 / 5 TYR A  99
ILE A 163
ARG A 120
GLY A 117
 None
 1.33A 2du8G-1nzjA:
2.0		 2du8G-1nzjA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		5 / 12 THR A 198
LEU A 194
ARG A   9
ARG A  36
TYR A   6
 None
 1.34A 2vaxK-1nzjA:
0.8		 2vaxK-1nzjA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		4 / 7 LEU A  64
LEU A  61
PRO A  14
ILE A  60
 None
 0.92A 3s56B-1nzjA:
undetectable		 3s56B-1nzjA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		4 / 6 CYH A 103
THR A 104
CYH A 101
ILE A 162
 ZN  A 700 (-2.3A)
None
ZN  A 700 (-2.3A)
None
 1.45A 3w9tB-1nzjA:
0.0		 3w9tB-1nzjA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		4 / 5 TYR A  67
LEU A  61
GLU A  17
VAL A  53
 None
 1.31A 4nkvA-1nzjA:
undetectable		 4nkvA-1nzjA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		4 / 5 LEU A  23
ALA A 249
VAL A 267
ILE A 270
 None
 0.90A 4xe3A-1nzjA:
undetectable		 4xe3A-1nzjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		4 / 5 LEU A  23
ALA A 249
VAL A 267
ILE A 270
 None
 0.84A 4xe3B-1nzjA:
undetectable		 4xe3B-1nzjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		3 / 3 ASP A 167
LEU A  89
ARG A  86
 None
 0.90A 5e8qA-1nzjA:
undetectable		 5e8qA-1nzjA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		5 / 12 LEU A  18
PHE A  10
ALA A 221
ALA A 249
ILE A 248
 None
 1.03A 5veuB-1nzjA:
undetectable		 5veuB-1nzjA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 1nzj HYPOTHETICAL PROTEIN
YADB
(Escherichia
coli) 		5 / 12 ILE A   7
TYR A 205
ARG A  43
LEU A  41
LEU A  76
 None
 1.32A 5zwrB-1nzjA:
undetectable		 5zwrB-1nzjA:
22.44