SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA156_1
(CALMODULIN)		 1o1c SKELETAL MUSCLE
MYOSIN II REGULATORY
LIGHT CHAIN
(Gallus
gallus) 		5 / 8 ILE B  42
LEU B  47
MET B  67
ILE B  75
MET B  83
 None
 1.28A 1linA-1o1cB:
10.3		 1linA-1o1cB:
36.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 1o1c SKELETAL MUSCLE
MYOSIN II REGULATORY
LIGHT CHAIN
(Gallus
gallus) 		4 / 4 PHE B  31
LYS B  28
ILE B  42
THR B  82
 None
 1.44A 3ia4B-1o1cB:
undetectable		 3ia4B-1o1cB:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1o1c SKELETAL MUSCLE
MYOSIN II REGULATORY
LIGHT CHAIN
(Gallus
gallus) 		3 / 3 GLU B  49
ASP B  45
ASP B  35
 None
 0.63A 4gc9A-1o1cB:
undetectable		 4gc9A-1o1cB:
19.93