SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 PHE A  17
ASN A  61
PHE A  63
ILE A  71
VAL A  83
 None
 1.01A 2ft9A-1o1uA:
17.6		 2ft9A-1o1uA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1o1u GASTROTROPIN
(Homo
sapiens) 		4 / 7 PHE A  17
LEU A  21
GLU A 110
ARG A 121
 None
 1.04A 2jn3A-1o1uA:
18.0		 2jn3A-1o1uA:
41.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 TRP A  49
ASN A  61
PHE A  63
VAL A  83
LEU A  90
 None
 0.73A 3elzA-1o1uA:
16.2		 3elzA-1o1uA:
56.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		6 / 12 TRP A  49
GLN A  51
PHE A  63
VAL A  83
LEU A  90
TYR A  97
 None
 0.87A 3elzA-1o1uA:
16.2		 3elzA-1o1uA:
56.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 11 TRP A  49
GLN A  51
VAL A  83
LEU A  90
TYR A  97
 None
 0.84A 3elzB-1o1uA:
15.7		 3elzB-1o1uA:
56.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 11 TRP A  49
GLN A  51
VAL A  83
TYR A  97
GLN A  99
 None
 1.15A 3elzB-1o1uA:
15.7		 3elzB-1o1uA:
56.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 TRP A  49
GLN A  51
VAL A  83
LEU A  90
TYR A  97
 None
 0.88A 3elzC-1o1uA:
14.2		 3elzC-1o1uA:
56.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 TRP A  49
GLN A  51
VAL A  83
TYR A  97
GLN A  99
 None
 1.22A 3elzC-1o1uA:
14.2		 3elzC-1o1uA:
56.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 TRP A  49
GLN A  51
VAL A  83
TYR A  97
GLN A  99
 None
 1.01A 3em0A-1o1uA:
16.3		 3em0A-1o1uA:
56.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 PHE A  17
TRP A  49
ASN A  61
VAL A  83
LEU A  90
 None
 0.87A 3em0B-1o1uA:
16.5		 3em0B-1o1uA:
56.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 PHE A  17
TRP A  49
GLN A  51
VAL A  83
LEU A  90
 None
 0.73A 3em0B-1o1uA:
16.5		 3em0B-1o1uA:
56.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 1o1u GASTROTROPIN
(Homo
sapiens) 		4 / 6 GLU A 110
ILE A  36
THR A  38
TYR A 119
 None
 1.33A 4qwpA-1o1uA:
0.0		 4qwpA-1o1uA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 1o1u GASTROTROPIN
(Homo
sapiens) 		4 / 5 GLU A 110
ILE A  36
THR A  38
TYR A 119
 None
 1.29A 4qwpB-1o1uA:
0.0		 4qwpB-1o1uA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1o1u GASTROTROPIN
(Homo
sapiens) 		3 / 3 THR A  60
SER A  50
ASP A  43
 None
 0.82A 5kvaA-1o1uA:
undetectable		 5kvaA-1o1uA:
18.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 GLN A  51
ILE A  71
PHE A  94
VAL A  83
SER A 101
 None
 1.23A 5l8oB-1o1uA:
17.5		 5l8oB-1o1uA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 GLN A  51
ILE A  71
VAL A  83
SER A 101
GLU A 110
 None
 1.38A 5l8oB-1o1uA:
17.5		 5l8oB-1o1uA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 TRP A  49
GLN A  51
ILE A  71
THR A  73
GLU A 110
 None
 1.10A 5l8oB-1o1uA:
17.5		 5l8oB-1o1uA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		8 / 12 TYR A  14
TRP A  49
GLN A  51
ILE A  71
LEU A  90
SER A 101
GLU A 110
SER A 112
 None
 0.87A 5l8oB-1o1uA:
17.5		 5l8oB-1o1uA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 1o1u GASTROTROPIN
(Homo
sapiens) 		8 / 12 TYR A  14
TRP A  49
GLN A  51
ILE A  71
LEU A  90
VAL A  92
SER A 101
SER A 112
 None
 0.95A 5l8oB-1o1uA:
17.5		 5l8oB-1o1uA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1o1u GASTROTROPIN
(Homo
sapiens) 		5 / 12 SER A  69
VAL A  91
THR A 100
PHE A  47
PHE A   2
 None
 1.14A 6a93B-1o1uA:
undetectable		 6a93B-1o1uA:
13.16