SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		3 / 3 SER A 111
VAL A  44
LEU A  81
 None
 0.64A 1yajG-1o1zA:
1.4		 1yajG-1o1zA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		3 / 3 GLU A  97
HIS A   6
GLU A  33
 None
 0.69A 2x45B-1o1zA:
undetectable		 2x45B-1o1zA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		3 / 3 GLU A  97
HIS A   6
GLU A  33
 None
 0.71A 2x45C-1o1zA:
undetectable		 2x45C-1o1zA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		3 / 3 HIS A  48
SER A  10
GLU A  15
 None
 0.90A 3s8pA-1o1zA:
0.0		 3s8pA-1o1zA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		5 / 12 GLY A   8
GLY A   5
GLU A  15
ALA A  20
TYR A  13
 None
 1.45A 3t7sC-1o1zA:
undetectable		 3t7sC-1o1zA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		5 / 8 GLY A   8
LYS A  12
SER A  10
TYR A   9
GLU A 214
 None
 1.17A 3u9hA-1o1zA:
undetectable		 3u9hA-1o1zA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		5 / 8 GLY A   8
LYS A  12
SER A  10
TYR A   9
GLU A 214
 None
 1.18A 3u9hB-1o1zA:
undetectable		 3u9hB-1o1zA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		5 / 8 GLY A   8
LYS A  12
SER A  10
TYR A   9
GLU A 214
 None
 1.15A 4bjcA-1o1zA:
undetectable		 4bjcA-1o1zA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 1o1z GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Thermotoga
maritima) 		5 / 9 VAL A 191
HIS A 164
GLY A 209
LEU A 217
ASP A 213
 None
 1.39A 6c2mC-1o1zA:
undetectable		 6c2mC-1o1zA:
15.38