SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o3u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1o3u CONSERVED
HYPOTHETICAL PROTEIN
TM0613
(Thermotoga
maritima) 		4 / 8 ALA A 109
LEU A   8
ALA A  11
LYS A  12
 None
 0.63A 1e7cA-1o3uA:
undetectable		 1e7cA-1o3uA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1o3u CONSERVED
HYPOTHETICAL PROTEIN
TM0613
(Thermotoga
maritima) 		3 / 3 VAL A  51
LEU A  55
VAL A  35
 None
 0.49A 4wq4A-1o3uA:
undetectable		 4wq4A-1o3uA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1o3u CONSERVED
HYPOTHETICAL PROTEIN
TM0613
(Thermotoga
maritima) 		4 / 7 GLU A  67
ILE A 112
CYH A 116
ILE A  64
 None
 0.97A 4xumA-1o3uA:
undetectable		 4xumA-1o3uA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1o3u CONSERVED
HYPOTHETICAL PROTEIN
TM0613
(Thermotoga
maritima) 		4 / 9 TYR A 108
LYS A 111
ILE A 112
LEU A 119
 None
 0.67A 5vkqB-1o3uA:
undetectable
5vkqC-1o3uA:
undetectable		 5vkqB-1o3uA:
6.22
5vkqC-1o3uA:
6.22