SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o3x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1o3x ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		3 / 3 ALA A 283
ASN A 286
LEU A 287
 None
 0.35A 5i1nB-1o3xA:
0.1		 5i1nB-1o3xA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1o3x ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		3 / 3 ALA A 283
ASN A 286
LEU A 287
 None
 0.38A 5i1oA-1o3xA:
undetectable		 5i1oA-1o3xA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1o3x ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 6 ARG A 214
ALA A 276
LEU A 277
ALA A 267
 None
 1.12A 6fosB-1o3xA:
2.6		 6fosB-1o3xA:
20.83