SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o50'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 1o50 CBS
DOMAIN-CONTAINING
PREDICTED PROTEIN
TM0935
(Thermotoga
maritima) 		3 / 3 ASP A  28
LEU A  31
HIS A  63
 None
 0.72A 1qknA-1o50A:
undetectable		 1qknA-1o50A:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 1o50 CBS
DOMAIN-CONTAINING
PREDICTED PROTEIN
TM0935
(Thermotoga
maritima) 		5 / 12 ILE A  30
THR A  36
VAL A  53
ILE A  51
ILE A  26
 None
 1.31A 2yzqA-1o50A:
14.9		 2yzqA-1o50A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 1o50 CBS
DOMAIN-CONTAINING
PREDICTED PROTEIN
TM0935
(Thermotoga
maritima) 		5 / 11 ASN A  45
GLY A 124
PRO A 118
GLU A 134
MET A  98
 None
 1.27A 4a6nA-1o50A:
undetectable		 4a6nA-1o50A:
18.35