SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o5j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 1o5j PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		5 / 10 LEU A  69
HIS A  73
LEU A  21
ILE A  27
ALA A  53
 None
 0.96A 2bxeB-1o5jA:
undetectable		 2bxeB-1o5jA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 1o5j PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		5 / 12 LEU A  69
HIS A  73
LEU A  21
ILE A  27
ALA A  53
 None
 1.02A 2bxqA-1o5jA:
undetectable		 2bxqA-1o5jA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 1o5j PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		5 / 9 ILE A  80
LEU A  69
LYS A  56
ILE A   2
PHE A  55
 None
 1.33A 3sj4X-1o5jA:
undetectable		 3sj4X-1o5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1o5j PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		5 / 8 ILE A  80
LEU A  69
LYS A  56
ILE A   2
PHE A  55
 None
 1.45A 4hb6A-1o5jA:
undetectable		 4hb6A-1o5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1o5j PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		5 / 8 ILE A  80
LEU A  69
LYS A  56
ILE A   2
PHE A  55
 None
 1.30A 4hb8A-1o5jA:
undetectable		 4hb8A-1o5jA:
20.19