SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o6b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 THR A 115
GLU A 114
LEU A  74
ILE A  75
LEU A  90
 None
 1.42A 3gwxB-1o6bA:
undetectable		 3gwxB-1o6bA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ILE A  22
GLY A  17
VAL A 142
PRO A  13
LEU A 154
 None
ADP  A 173 (-3.6A)
None
None
None
 1.12A 3v8vA-1o6bA:
2.3		 3v8vA-1o6bA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Bacillus
subtilis) 		4 / 7 PRO A  13
VAL A 132
ALA A 136
PHE A 158
 None
 0.59A 4lb2A-1o6bA:
undetectable		 4lb2A-1o6bA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Bacillus
subtilis) 		3 / 3 GLU A  50
ASP A  12
PRO A  13
 None
 0.74A 6berA-1o6bA:
undetectable		 6berA-1o6bA:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ILE A  22
ILE A  62
VAL A  34
ILE A  65
PHE A  29
 None
 1.20A 6hlpA-1o6bA:
4.3		 6hlpA-1o6bA:
14.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Bacillus
subtilis) 		4 / 5 GLY A   9
HIS A  18
SER A 128
SER A 129
 ADP  A 173 (-3.3A)
ADP  A 173 ( 3.9A)
PO4  A 170 (-4.6A)
PO4  A 170 (-3.4A)
 0.47A 6jmjA-1o6bA:
25.2		 6jmjA-1o6bA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Bacillus
subtilis) 		6 / 7 GLY A   9
PHE A  11
HIS A  18
ARG A  91
SER A 128
SER A 129
 ADP  A 173 (-3.3A)
ADP  A 173 (-3.8A)
ADP  A 173 ( 3.9A)
None
PO4  A 170 (-4.6A)
PO4  A 170 (-3.4A)
 0.52A 6jnhA-1o6bA:
25.3		 6jnhA-1o6bA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Bacillus
subtilis) 		5 / 6 GLY A   9
HIS A  18
ARG A  91
SER A 128
SER A 129
 ADP  A 173 (-3.3A)
ADP  A 173 ( 3.9A)
None
PO4  A 170 (-4.6A)
PO4  A 170 (-3.4A)
 0.56A 6jogA-1o6bA:
25.3		 6jogA-1o6bA:
42.33