SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o77'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 1o77 TOLL-LIKE RECEPTOR 2
(Homo
sapiens) 		4 / 4 ASP A 651
LEU A 736
LEU A 703
LEU A 737
 None
 1.23A 1u18A-1o77A:
0.0		 1u18A-1o77A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1o77 TOLL-LIKE RECEPTOR 2
(Homo
sapiens) 		5 / 10 PRO A 765
LEU A 778
ILE A 782
ALA A 643
VAL A 702
 None
 1.42A 5m0oA-1o77A:
undetectable		 5m0oA-1o77A:
14.95