SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		3 / 4 LYS A 119
ALA A 120
MET A 202
 None
 1.05A 1hk3A-1o7xA:
2.2		 1hk3A-1o7xA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		3 / 3 ILE A 123
ILE A 124
THR A 100
 None
 0.64A 1rg7A-1o7xA:
undetectable		 1rg7A-1o7xA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		4 / 6 ALA A 176
LEU A 179
ILE A 178
SER A 337
 None
 1.05A 1sbrA-1o7xA:
1.3
1sbrB-1o7xA:
1.1		 1sbrA-1o7xA:
19.13
1sbrB-1o7xA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		4 / 6 LEU A  18
LEU A  38
LEU A 340
ILE A  35
 None
 1.02A 1z95A-1o7xA:
undetectable		 1z95A-1o7xA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		4 / 6 LEU A 210
ILE A  83
ALA A 332
LEU A 333
 None
 0.88A 3kk6B-1o7xA:
undetectable		 3kk6B-1o7xA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		5 / 11 GLU A 223
GLY A 317
ALA A 222
ILE A 318
ALA A 322
 None
 1.23A 3nmuB-1o7xA:
1.6
3nmuJ-1o7xA:
undetectable		 3nmuB-1o7xA:
22.86
3nmuJ-1o7xA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		5 / 8 PHE A 325
PHE A 320
ALA A 172
PHE A 156
ALA A 153
 None
 1.36A 3t3sD-1o7xA:
0.4		 3t3sD-1o7xA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 274
ALA A 322
LEU A 157
ARG A 163
LEU A 333
 None
 1.46A 3vhuA-1o7xA:
undetectable		 3vhuA-1o7xA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		4 / 7 LEU A  18
LEU A  38
LEU A 340
ILE A  35
 None
 1.03A 4okwA-1o7xA:
undetectable		 4okwA-1o7xA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		4 / 6 LEU A 298
LEU A 253
PHE A 242
ILE A 291
 None
 1.00A 4y4dA-1o7xA:
undetectable		 4y4dA-1o7xA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A 219
THR A 331
THR A 339
ALA A 187
ALA A 209
 None
 0.95A 5kpcA-1o7xA:
undetectable		 5kpcA-1o7xA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		3 / 3 LEU A 295
ALA A 292
LEU A 253
 None
 0.51A 5uunB-1o7xA:
undetectable		 5uunB-1o7xA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		3 / 3 LEU A 340
THR A  16
ASN A  17
 None
 0.68A 6baaE-1o7xA:
undetectable		 6baaE-1o7xA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		3 / 3 LEU A 340
THR A  16
ASN A  17
 None
 0.68A 6baaF-1o7xA:
undetectable		 6baaF-1o7xA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		3 / 3 LEU A 340
THR A  16
ASN A  17
 None
 0.69A 6baaG-1o7xA:
undetectable		 6baaG-1o7xA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		3 / 3 LEU A 340
THR A  16
ASN A  17
 None
 0.69A 6baaH-1o7xA:
undetectable		 6baaH-1o7xA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HXI_B_ACTB706_0
(SUCCINYL-COA LIGASE
(ADP-FORMING)
SUBUNIT ALPHA)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		4 / 5 HIS A 183
ARG A 267
PHE A 334
ARG A 338
 None
 0.42A 6hxiB-1o7xA:
14.4		 6hxiB-1o7xA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HXI_D_ACTD703_0
(SUCCINYL-COA LIGASE
(ADP-FORMING)
SUBUNIT ALPHA)		 1o7x CITRATE SYNTHASE
(Sulfolobus
solfataricus) 		5 / 5 HIS A 183
ARG A 267
ASP A 313
PHE A 334
ARG A 338
 None
 0.61A 6hxiD-1o7xA:
16.0		 6hxiD-1o7xA:
22.43