SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o8v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_A_MK1A901_2 (POL POLYPROTEIN)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	3 / 3	ASP A 17 VAL A 25 PRO A 76	None None PLM A1136 (-4.6A)	0.78A	2avvA-1o8vA: undetectable	2avvA-1o8vA: 20.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_A_TDZA201_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	6 / 12	PHE A 16 VAL A 25 SER A 54 ASP A 77 ARG A 79 ARG A 127	PLM A1136 (-4.7A) None PLM A1136 ( 4.9A) PLM A1136 (-3.8A) PLM A1136 (-4.6A) PLM A1136 (-4.4A)	1.16A	2qm9A-1o8vA: 23.5	2qm9A-1o8vA: 36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_A_TDZA201_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	9 / 12	PHE A 16 VAL A 25 SER A 54 SER A 56 THR A 61 ASP A 77 ARG A 79 ARG A 127 TYR A 129	PLM A1136 (-4.7A) None PLM A1136 ( 4.9A) PLM A1136 ( 3.8A) None PLM A1136 (-3.8A) PLM A1136 (-4.6A) PLM A1136 (-4.4A) PLM A1136 (-4.6A)	0.54A	2qm9A-1o8vA: 23.5	2qm9A-1o8vA: 36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_B_TDZB202_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	5 / 12	PHE A 16 VAL A 25 SER A 54 ARG A 79 ARG A 127	PLM A1136 (-4.7A) None PLM A1136 ( 4.9A) PLM A1136 (-4.6A) PLM A1136 (-4.4A)	1.13A	2qm9B-1o8vA: 24.2	2qm9B-1o8vA: 36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_B_TDZB202_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	8 / 12	PHE A 16 VAL A 25 SER A 54 SER A 56 THR A 61 ARG A 79 ARG A 127 TYR A 129	PLM A1136 (-4.7A) None PLM A1136 ( 4.9A) PLM A1136 ( 3.8A) None PLM A1136 (-4.6A) PLM A1136 (-4.4A) PLM A1136 (-4.6A)	0.58A	2qm9B-1o8vA: 24.2	2qm9B-1o8vA: 36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_B_TDZB202_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	8 / 12	PHE A 16 VAL A 25 SER A 54 SER A 56 THR A 61 ILE A 105 ARG A 127 TYR A 129	PLM A1136 (-4.7A) None PLM A1136 ( 4.9A) PLM A1136 ( 3.8A) None None PLM A1136 (-4.4A) PLM A1136 (-4.6A)	0.65A	2qm9B-1o8vA: 24.2	2qm9B-1o8vA: 36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2QM9_B_TDZB202_2 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	4 / 4	MET A 20 PRO A 38 ASP A 77 ARG A 107	PLM A1136 (-3.5A) None PLM A1136 (-3.8A) PLM A1136 (-3.9A)	0.48A	2qm9B-1o8vA: 24.2	2qm9B-1o8vA: 36.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARR_A_PNXA607_1 (CHITINASE A)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	4 / 7	VAL A 81 SER A 83 HIS A 94 THR A 75	None None CSO A 63 ( 4.8A) PLM A1136 ( 4.9A)	0.79A	3arrA-1o8vA: undetectable	3arrA-1o8vA: 11.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3P6G_A_IZPA133_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	10 / 12	PHE A 16 MET A 20 VAL A 25 PRO A 38 ASP A 77 ARG A 79 ILE A 105 ARG A 107 ARG A 127 TYR A 129	PLM A1136 (-4.7A) PLM A1136 (-3.5A) None None PLM A1136 (-3.8A) PLM A1136 (-4.6A) None PLM A1136 (-3.9A) PLM A1136 (-4.4A) PLM A1136 (-4.6A)	0.55A	3p6gA-1o8vA: 23.7	3p6gA-1o8vA: 41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3P6G_A_IZPA133_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	7 / 12	PHE A 16 MET A 20 VAL A 25 PRO A 38 CYH A 125 ARG A 127 TYR A 129	PLM A1136 (-4.7A) PLM A1136 (-3.5A) None None None PLM A1136 (-4.4A) PLM A1136 (-4.6A)	1.24A	3p6gA-1o8vA: 23.7	3p6gA-1o8vA: 41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3P6H_A_IBPA133_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	6 / 7	PHE A 16 MET A 20 ASP A 77 ILE A 105 ARG A 127 TYR A 129	PLM A1136 (-4.7A) PLM A1136 (-3.5A) PLM A1136 (-3.8A) None PLM A1136 (-4.4A) PLM A1136 (-4.6A)	0.58A	3p6hA-1o8vA: 23.7	3p6hA-1o8vA: 41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5LJE_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	1o8v	FATTY ACID BINDING PROTEIN HOMOLOG (Echinococcus granulosus)	5 / 12	PHE A 16 PRO A 38 LEU A 40 SER A 56 PHE A 58	PLM A1136 (-4.7A) None None PLM A1136 ( 3.8A) PLM A1136 ( 4.9A)	1.09A	5ljeA-1o8vA: 19.9	5ljeA-1o8vA: 32.62

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AVV_A_MK1A901_2","POL POLYPROTEIN","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",3,"ASP A  17;VAL A  25;PRO A  76","None;None;PLM A1136 (-4.6A)","0.78A","2avvA-1o8vA:undetectable","2avvA-1o8vA:20.42"],["2QM9_A_TDZA201_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",6,"PHE A  16;VAL A  25;SER A  54;ASP A  77;ARG A  79;ARG A 127","PLM A1136 (-4.7A);None;PLM A1136 ( 4.9A);PLM A1136 (-3.8A);PLM A1136 (-4.6A);PLM A1136 (-4.4A)","1.16A","2qm9A-1o8vA:23.5","2qm9A-1o8vA:36.94"],["2QM9_A_TDZA201_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",9,"PHE A  16;VAL A  25;SER A  54;SER A  56;THR A  61;ASP A  77;ARG A  79;ARG A 127;TYR A 129","PLM A1136 (-4.7A);None;PLM A1136 ( 4.9A);PLM A1136 ( 3.8A);None;PLM A1136 (-3.8A);PLM A1136 (-4.6A);PLM A1136 (-4.4A);PLM A1136 (-4.6A)","0.54A","2qm9A-1o8vA:23.5","2qm9A-1o8vA:36.94"],["2QM9_B_TDZB202_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",5,"PHE A  16;VAL A  25;SER A  54;ARG A  79;ARG A 127","PLM A1136 (-4.7A);None;PLM A1136 ( 4.9A);PLM A1136 (-4.6A);PLM A1136 (-4.4A)","1.13A","2qm9B-1o8vA:24.2","2qm9B-1o8vA:36.94"],["2QM9_B_TDZB202_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",8,"PHE A  16;VAL A  25;SER A  54;SER A  56;THR A  61;ARG A  79;ARG A 127;TYR A 129","PLM A1136 (-4.7A);None;PLM A1136 ( 4.9A);PLM A1136 ( 3.8A);None;PLM A1136 (-4.6A);PLM A1136 (-4.4A);PLM A1136 (-4.6A)","0.58A","2qm9B-1o8vA:24.2","2qm9B-1o8vA:36.94"],["2QM9_B_TDZB202_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",8,"PHE A  16;VAL A  25;SER A  54;SER A  56;THR A  61;ILE A 105;ARG A 127;TYR A 129","PLM A1136 (-4.7A);None;PLM A1136 ( 4.9A);PLM A1136 ( 3.8A);None;None;PLM A1136 (-4.4A);PLM A1136 (-4.6A)","0.65A","2qm9B-1o8vA:24.2","2qm9B-1o8vA:36.94"],["2QM9_B_TDZB202_2","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",4,"MET A  20;PRO A  38;ASP A  77;ARG A 107","PLM A1136 (-3.5A);None;PLM A1136 (-3.8A);PLM A1136 (-3.9A)","0.48A","2qm9B-1o8vA:24.2","2qm9B-1o8vA:36.94"],["3ARR_A_PNXA607_1","CHITINASE A","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",4,"VAL A  81;SER A  83;HIS A  94;THR A  75","None;None;CSO A  63 ( 4.8A);PLM A1136 ( 4.9A)","0.79A","3arrA-1o8vA:undetectable","3arrA-1o8vA:11.95"],["3P6G_A_IZPA133_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",10,"PHE A  16;MET A  20;VAL A  25;PRO A  38;ASP A  77;ARG A  79;ILE A 105;ARG A 107;ARG A 127;TYR A 129","PLM A1136 (-4.7A);PLM A1136 (-3.5A);None;None;PLM A1136 (-3.8A);PLM A1136 (-4.6A);None;PLM A1136 (-3.9A);PLM A1136 (-4.4A);PLM A1136 (-4.6A)","0.55A","3p6gA-1o8vA:23.7","3p6gA-1o8vA:41.84"],["3P6G_A_IZPA133_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",7,"PHE A  16;MET A  20;VAL A  25;PRO A  38;CYH A 125;ARG A 127;TYR A 129","PLM A1136 (-4.7A);PLM A1136 (-3.5A);None;None;None;PLM A1136 (-4.4A);PLM A1136 (-4.6A)","1.24A","3p6gA-1o8vA:23.7","3p6gA-1o8vA:41.84"],["3P6H_A_IBPA133_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",6,"PHE A  16;MET A  20;ASP A  77;ILE A 105;ARG A 127;TYR A 129","PLM A1136 (-4.7A);PLM A1136 (-3.5A);PLM A1136 (-3.8A);None;PLM A1136 (-4.4A);PLM A1136 (-4.6A)","0.58A","3p6hA-1o8vA:23.7","3p6hA-1o8vA:41.84"],["5LJE_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","1o8v","FATTY ACID BINDING PROTEIN HOMOLOG","Echinococcus granulosus",5,"PHE A  16;PRO A  38;LEU A  40;SER A  56;PHE A  58","PLM A1136 (-4.7A);None;None;PLM A1136 ( 3.8A);PLM A1136 ( 4.9A)","1.09A","5ljeA-1o8vA:19.9","5ljeA-1o8vA:32.62"]]