SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o91'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA151_0 (ILEAL BILE ACID-BINDING PROTEIN)	1o91	COLLAGEN ALPHA 1(VIII) CHAIN (Mus musculus)	4 / 7	TYR A 645 GLY A 650 VAL A 623 LEU A 637	None	0.91A	3elzA-1o91A: undetectable	3elzA-1o91A: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_M_TFPM201_1 (PROTEIN S100-A4)	1o91	COLLAGEN ALPHA 1(VIII) CHAIN (Mus musculus)	4 / 7	GLY A 641 PHE A 652 GLY A 737 PHE A 662	None	0.88A	3ko0M-1o91A: undetectable 3ko0P-1o91A: undetectable	3ko0M-1o91A: 19.44 3ko0P-1o91A: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8X_A_NIMA701_2 (PROSTAGLANDIN G/H SYNTHASE 1)	1o91	COLLAGEN ALPHA 1(VIII) CHAIN (Mus musculus)	3 / 3	VAL A 666 SER A 733 LEU A 725	None	0.71A	3n8xA-1o91A: undetectable	3n8xA-1o91A: 15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ICX_E_SC2E1_1 (CETUXIMAB FAB LIGHT CHAIN MEDITOPE)	1o91	COLLAGEN ALPHA 1(VIII) CHAIN (Mus musculus)	3 / 3	VAL A 673 GLN A 698 CYH A 668	None	0.75A	5icxA-1o91A: undetectable 5icxE-1o91A: undetectable	5icxA-1o91A: 22.42 5icxE-1o91A: 5.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ELZ_A_CHDA151_0","ILEAL BILE ACID-BINDING PROTEIN","1o91","COLLAGEN ALPHA 1(VIII) CHAIN","Mus musculus",4,"TYR A 645;GLY A 650;VAL A 623;LEU A 637","None","0.91A","3elzA-1o91A:undetectable","3elzA-1o91A:23.16"],["3KO0_M_TFPM201_1","PROTEIN S100-A4;PROTEIN S100-A4","1o91","COLLAGEN ALPHA 1(VIII) CHAIN","Mus musculus",4,"GLY A 641;PHE A 652;GLY A 737;PHE A 662","None","0.88A","3ko0M-1o91A:undetectable;3ko0P-1o91A:undetectable","3ko0M-1o91A:19.44;3ko0P-1o91A:19.44"],["3N8X_A_NIMA701_2","PROSTAGLANDIN G\/H SYNTHASE 1","1o91","COLLAGEN ALPHA 1(VIII) CHAIN","Mus musculus",3,"VAL A 666;SER A 733;LEU A 725","None","0.71A","3n8xA-1o91A:undetectable","3n8xA-1o91A:15.52"],["5ICX_E_SC2E1_1","CETUXIMAB FAB LIGHT CHAIN;MEDITOPE","1o91","COLLAGEN ALPHA 1(VIII) CHAIN","Mus musculus",3,"VAL A 673;GLN A 698;CYH A 668","None","0.75A","5icxA-1o91A:undetectable;5icxE-1o91A:undetectable","5icxA-1o91A:22.42;5icxE-1o91A:5.92"]]