SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o9b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EIZ_A_SAMA301_0 (FTSJ)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	ALA A 114 GLY A 263 GLY A 257 TRP A 261 LEU A 269	None	0.99A	1eizA-1o9bA: 7.7	1eizA-1o9bA: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EJ0_A_SAMA301_0 (FTSJ)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	ALA A 114 GLY A 263 GLY A 257 TRP A 261 LEU A 269	None	0.99A	1ej0A-1o9bA: 7.7	1ej0A-1o9bA: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I9G_A_SAMA301_0 (HYPOTHETICAL PROTEIN RV2118C)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	ILE A 139 GLY A 131 GLY A 133 ALA A 138 LEU A 184	None NAI A 301 ( 4.2A) NAI A 301 (-3.0A) None None	1.29A	1i9gA-1o9bA: 8.4	1i9gA-1o9bA: 22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_A_BEZA524_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 6	THR A 268 PHE A 275 GLU A 265 GLY A 263	None	1.16A	1kqbA-1o9bA: undetectable 1kqbB-1o9bA: undetectable	1kqbA-1o9bA: 24.33 1kqbB-1o9bA: 24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_B_BEZB525_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 5	GLU A 265 GLY A 263 THR A 268 PHE A 275	None	1.16A	1kqbA-1o9bA: undetectable 1kqbB-1o9bA: undetectable	1kqbA-1o9bA: 24.33 1kqbB-1o9bA: 24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U72_A_MTXA188_1 (DIHYDROFOLATE REDUCTASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	ALA A 197 LEU A 200 PHE A 190 GLN A 188 ASN A 218	None	1.32A	1u72A-1o9bA: undetectable	1u72A-1o9bA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_W_CHDW4060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 7	ILE A 115 MET A 127 THR A 126 LEU A 148	None	1.01A	1v54N-1o9bA: undetectable 1v54W-1o9bA: undetectable	1v54N-1o9bA: 21.49 1v54W-1o9bA: 11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_F_BEZF5023_0 (CES1 PROTEIN)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 6	LEU A 129 GLY A 140 LEU A 148 ILE A 115 HIS A 111	None	1.39A	1yajF-1o9bA: undetectable	1yajF-1o9bA: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YVP_B_ACTB2002_0 (60-KDA SS-A/RO RIBONUCLEOPROTEIN)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 6	ALA A 135 SER A 136 THR A 204 ASN A 202	NAI A 301 (-3.7A) None NAI A 301 (-4.4A) None	1.07A	1yvpB-1o9bA: undetectable	1yvpB-1o9bA: 19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HS2_A_017A201_1 (PROTEASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	LEU A 129 GLY A 143 ALA A 144 GLY A 124 ILE A 151	None	0.97A	2hs2A-1o9bA: undetectable	2hs2A-1o9bA: 18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2I91_A_ACTA601_0 (60 KDA SS-A/RO RIBONUCLEOPROTEIN)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 7	ALA A 135 SER A 136 THR A 204 ASN A 202	NAI A 301 (-3.7A) None NAI A 301 (-4.4A) None	0.97A	2i91A-1o9bA: undetectable	2i91A-1o9bA: 19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2I91_B_ACTB602_0 (60 KDA SS-A/RO RIBONUCLEOPROTEIN)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 7	ALA A 135 SER A 136 THR A 204 ASN A 202	NAI A 301 (-3.7A) None NAI A 301 (-4.4A) None	0.96A	2i91B-1o9bA: undetectable	2i91B-1o9bA: 19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QWX_B_ML1B233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 7	MET A 284 GLY A 34 PHE A 267 PHE A 275	None	0.93A	2qwxA-1o9bA: 6.4 2qwxB-1o9bA: 6.3	2qwxA-1o9bA: 23.47 2qwxB-1o9bA: 23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0Z_O_C41O1327_1 (RENIN)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	6 / 12	GLY A 143 ALA A 164 VAL A 171 GLY A 140 SER A 136 ILE A 199	None	1.16A	2v0zO-1o9bA: undetectable	2v0zO-1o9bA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKP_B_478B200_1 (PROTEASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 8	GLY A 133 ALA A 132 VAL A 181 GLY A 140 ILE A 139	NAI A 301 (-3.0A) NAI A 301 (-4.0A) None None None	1.12A	3ekpA-1o9bA: undetectable	3ekpA-1o9bA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKP_B_478B200_1 (PROTEASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 8	LEU A 129 GLY A 143 ALA A 144 GLY A 124 ILE A 151	None	1.18A	3ekpA-1o9bA: undetectable	3ekpA-1o9bA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKT_D_017D200_2 (PROTEASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 11	LEU A 129 GLY A 143 ALA A 144 GLY A 124 ILE A 151	None	1.16A	3ektD-1o9bA: undetectable	3ektD-1o9bA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GN8_A_DEXA247_1 (GLUCOCORTICOID RECEPTOR 2)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	ASN A 105 GLN A 266 MET A 258 THR A 137 VAL A 88	None None NAI A 301 (-3.9A) None None	1.20A	3gn8A-1o9bA: undetectable	3gn8A-1o9bA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N2O_C_AG2C1002_1 (BIOSYNTHETIC ARGININE DECARBOXYLASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 8	HIS A 224 SER A 196 LEU A 148 ASP A 198	None	1.23A	3n2oC-1o9bA: undetectable 3n2oD-1o9bA: undetectable	3n2oC-1o9bA: 19.14 3n2oD-1o9bA: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NHX_A_ASDA126_1 (STEROID DELTA-ISOMERASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	TYR A 234 LEU A 259 SER A 22 PHE A 286 VAL A 280	NAI A 301 (-4.4A) NAI A 301 (-3.8A) None None None	1.49A	3nhxA-1o9bA: 0.0	3nhxA-1o9bA: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1477_0 (MJ0495-LIKE PROTEIN)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 6	THR A 137 GLY A 140 ILE A 151 LEU A 87	None	0.91A	4ac9C-1o9bA: 3.6	4ac9C-1o9bA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1477_0 (TRANSLATION ELONGATION FACTOR SELB)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 6	THR A 137 GLY A 140 ILE A 151 LEU A 87	None	0.89A	4acaC-1o9bA: 3.5	4acaC-1o9bA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1478_0 (TRANSLATION ELONGATION FACTOR SELB)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 7	GLY A 108 THR A 109 ILE A 112 THR A 175	None	0.95A	4acaC-1o9bA: 3.4	4acaC-1o9bA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1477_0 (TRANSLATION ELONGATION FACTOR SELB)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 6	THR A 137 GLY A 140 ILE A 151 LEU A 87	None	0.91A	4acbC-1o9bA: 3.1	4acbC-1o9bA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYR_B_RITB301_2 (HIV-1 PROTEASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 8	ARG A 156 GLY A 134 ALA A 135 ASP A 107	NAI A 301 (-3.5A) NAI A 301 (-3.1A) NAI A 301 (-3.7A) PO4 A 302 (-3.0A)	0.76A	4eyrB-1o9bA: undetectable	4eyrB-1o9bA: 18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HB8_A_DXCA75_0 (PPCA)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 8	ILE A 151 LEU A 129 ILE A 112 GLY A 134	None None None NAI A 301 (-3.1A)	0.80A	4hb8A-1o9bA: undetectable	4hb8A-1o9bA: 16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYN_B_RTLB201_0 (RETINOL-BINDING PROTEIN 2)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	MET A 127 ILE A 151 THR A 204 LEU A 241 LEU A 200	None None NAI A 301 (-4.4A) None None	1.06A	4qynB-1o9bA: undetectable	4qynB-1o9bA: 19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZT_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	MET A 127 ILE A 151 THR A 204 LEU A 241 LEU A 200	None None NAI A 301 (-4.4A) None None	1.09A	4qztA-1o9bA: undetectable	4qztA-1o9bA: 19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZT_A_RTLA201_1 (RETINOL-BINDING PROTEIN 2)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	3 / 3	PHE A 190 THR A 239 LEU A 223	None	0.79A	4qztA-1o9bA: undetectable	4qztA-1o9bA: 19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_C_RTLC201_0 (RETINOL-BINDING PROTEIN 2)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	MET A 127 ILE A 151 THR A 204 LEU A 241 LEU A 200	None None NAI A 301 (-4.4A) None None	1.09A	4qzuC-1o9bA: undetectable	4qzuC-1o9bA: 19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BXN_H_BO2H301_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-3)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 11	THR A 93 GLN A 72 GLY A 103 ALA A 85 THR A 82	None PO4 A 303 (-3.6A) None None None	1.19A	5bxnH-1o9bA: undetectable 5bxnI-1o9bA: undetectable	5bxnH-1o9bA: 22.60 5bxnI-1o9bA: 22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZX_A_9F2A1102_1 (DNA CROSS-LINK REPAIR 1A PROTEIN)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 8	THR A 93 GLN A 26 ILE A 10 GLY A 65	None	0.98A	5nzxA-1o9bA: 2.3	5nzxA-1o9bA: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZY_A_CE3A1102_1 (DNA CROSS-LINK REPAIR 1A PROTEIN)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	4 / 7	THR A 93 GLN A 26 ILE A 10 GLY A 65	None	0.97A	5nzyA-1o9bA: 2.2	5nzyA-1o9bA: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T2Z_B_017B201_1 (PROTEASE)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 12	LEU A 129 GLY A 143 ALA A 144 GLY A 124 ILE A 151	None	1.00A	5t2zA-1o9bA: undetectable	5t2zA-1o9bA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BAA_E_GBME2001_2 (ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	3 / 3	LEU A 12 THR A 106 ASN A 105	None	0.58A	6baaE-1o9bA: undetectable	6baaE-1o9bA: 10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BAA_F_GBMF2001_2 (ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	3 / 3	LEU A 12 THR A 106 ASN A 105	None	0.57A	6baaF-1o9bA: undetectable	6baaF-1o9bA: 10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BAA_G_GBMG2001_2 (ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	3 / 3	LEU A 12 THR A 106 ASN A 105	None	0.58A	6baaG-1o9bA: undetectable	6baaG-1o9bA: 10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BAA_H_GBMH2001_2 (ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	3 / 3	LEU A 12 THR A 106 ASN A 105	None	0.58A	6baaH-1o9bA: undetectable	6baaH-1o9bA: 10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DLZ_A_CYZA1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 10	PRO A 23 SER A 20 ASP A 107 ILE A 10 GLY A 11	None None PO4 A 302 (-3.0A) None None	1.42A	6dlzA-1o9bA: 5.7 6dlzD-1o9bA: 3.4	6dlzA-1o9bA: 13.59 6dlzD-1o9bA: 13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DLZ_C_CYZC1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 10	ILE A 10 GLY A 11 PRO A 23 SER A 20 ASP A 107	None None None None PO4 A 302 (-3.0A)	1.42A	6dlzB-1o9bA: 5.9 6dlzC-1o9bA: 5.9	6dlzB-1o9bA: 13.59 6dlzC-1o9bA: 13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DM1_A_CYZA1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 10	PRO A 23 SER A 20 ASP A 107 ILE A 10 GLY A 11	None None PO4 A 302 (-3.0A) None None	1.42A	6dm1A-1o9bA: 5.8 6dm1D-1o9bA: 3.2	6dm1A-1o9bA: 13.59 6dm1D-1o9bA: 13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DM1_C_CYZC1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 10	ILE A 10 GLY A 11 PRO A 23 SER A 20 ASP A 107	None None None None PO4 A 302 (-3.0A)	1.42A	6dm1B-1o9bA: 4.6 6dm1C-1o9bA: 2.3	6dm1B-1o9bA: 13.59 6dm1C-1o9bA: 13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HUP_B_DZPB502_0 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOB UTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3)	1o9b	HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB (Escherichia coli)	5 / 11	ILE A 94 LEU A 56 LEU A 12 MET A 13 PHE A 42	None	1.43A	6hupA-1o9bA: 0.0 6hupB-1o9bA: 0.0	6hupA-1o9bA: 18.29 6hupB-1o9bA: 16.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EIZ_A_SAMA301_0","FTSJ","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"ALA A 114;GLY A 263;GLY A 257;TRP A 261;LEU A 269","None","0.99A","1eizA-1o9bA:7.7","1eizA-1o9bA:23.24"],["1EJ0_A_SAMA301_0","FTSJ","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"ALA A 114;GLY A 263;GLY A 257;TRP A 261;LEU A 269","None","0.99A","1ej0A-1o9bA:7.7","1ej0A-1o9bA:23.24"],["1I9G_A_SAMA301_0","HYPOTHETICAL PROTEIN RV2118C","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"ILE A 139;GLY A 131;GLY A 133;ALA A 138;LEU A 184","None;NAI A 301 ( 4.2A);NAI A 301 (-3.0A);None;None","1.29A","1i9gA-1o9bA:8.4","1i9gA-1o9bA:22.48"],["1KQB_A_BEZA524_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"THR A 268;PHE A 275;GLU A 265;GLY A 263","None","1.16A","1kqbA-1o9bA:undetectable;1kqbB-1o9bA:undetectable","1kqbA-1o9bA:24.33;1kqbB-1o9bA:24.33"],["1KQB_B_BEZB525_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"GLU A 265;GLY A 263;THR A 268;PHE A 275","None","1.16A","1kqbA-1o9bA:undetectable;1kqbB-1o9bA:undetectable","1kqbA-1o9bA:24.33;1kqbB-1o9bA:24.33"],["1U72_A_MTXA188_1","DIHYDROFOLATE REDUCTASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"ALA A 197;LEU A 200;PHE A 190;GLN A 188;ASN A 218","None","1.32A","1u72A-1o9bA:undetectable","1u72A-1o9bA:20.07"],["1V54_W_CHDW4060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"ILE A 115;MET A 127;THR A 126;LEU A 148","None","1.01A","1v54N-1o9bA:undetectable;1v54W-1o9bA:undetectable","1v54N-1o9bA:21.49;1v54W-1o9bA:11.74"],["1YAJ_F_BEZF5023_0","CES1 PROTEIN","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"LEU A 129;GLY A 140;LEU A 148;ILE A 115;HIS A 111","None","1.39A","1yajF-1o9bA:undetectable","1yajF-1o9bA:18.85"],["1YVP_B_ACTB2002_0","60-KDA SS-A\/RO RIBONUCLEOPROTEIN","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"ALA A 135;SER A 136;THR A 204;ASN A 202","NAI A 301 (-3.7A);None;NAI A 301 (-4.4A);None","1.07A","1yvpB-1o9bA:undetectable","1yvpB-1o9bA:19.26"],["2HS2_A_017A201_1","PROTEASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"LEU A 129;GLY A 143;ALA A 144;GLY A 124;ILE A 151","None","0.97A","2hs2A-1o9bA:undetectable","2hs2A-1o9bA:18.73"],["2I91_A_ACTA601_0","60 KDA SS-A\/RO RIBONUCLEOPROTEIN","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"ALA A 135;SER A 136;THR A 204;ASN A 202","NAI A 301 (-3.7A);None;NAI A 301 (-4.4A);None","0.97A","2i91A-1o9bA:undetectable","2i91A-1o9bA:19.26"],["2I91_B_ACTB602_0","60 KDA SS-A\/RO RIBONUCLEOPROTEIN","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"ALA A 135;SER A 136;THR A 204;ASN A 202","NAI A 301 (-3.7A);None;NAI A 301 (-4.4A);None","0.96A","2i91B-1o9bA:undetectable","2i91B-1o9bA:19.26"],["2QWX_B_ML1B233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"MET A 284;GLY A  34;PHE A 267;PHE A 275","None","0.93A","2qwxA-1o9bA:6.4;2qwxB-1o9bA:6.3","2qwxA-1o9bA:23.47;2qwxB-1o9bA:23.47"],["2V0Z_O_C41O1327_1","RENIN","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",6,"GLY A 143;ALA A 164;VAL A 171;GLY A 140;SER A 136;ILE A 199","None","1.16A","2v0zO-1o9bA:undetectable","2v0zO-1o9bA:20.63"],["3EKP_B_478B200_1","PROTEASE;PROTEASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"GLY A 133;ALA A 132;VAL A 181;GLY A 140;ILE A 139","NAI A 301 (-3.0A);NAI A 301 (-4.0A);None;None;None","1.12A","3ekpA-1o9bA:undetectable","3ekpA-1o9bA:17.82"],["3EKP_B_478B200_1","PROTEASE;PROTEASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"LEU A 129;GLY A 143;ALA A 144;GLY A 124;ILE A 151","None","1.18A","3ekpA-1o9bA:undetectable","3ekpA-1o9bA:17.82"],["3EKT_D_017D200_2","PROTEASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"LEU A 129;GLY A 143;ALA A 144;GLY A 124;ILE A 151","None","1.16A","3ektD-1o9bA:undetectable","3ektD-1o9bA:17.82"],["3GN8_A_DEXA247_1","GLUCOCORTICOID RECEPTOR 2","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"ASN A 105;GLN A 266;MET A 258;THR A 137;VAL A  88","None;None;NAI A 301 (-3.9A);None;None","1.20A","3gn8A-1o9bA:undetectable","3gn8A-1o9bA:20.81"],["3N2O_C_AG2C1002_1","BIOSYNTHETIC ARGININE DECARBOXYLASE;BIOSYNTHETIC ARGININE DECARBOXYLASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"HIS A 224;SER A 196;LEU A 148;ASP A 198","None","1.23A","3n2oC-1o9bA:undetectable;3n2oD-1o9bA:undetectable","3n2oC-1o9bA:19.14;3n2oD-1o9bA:19.14"],["3NHX_A_ASDA126_1","STEROID DELTA-ISOMERASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"TYR A 234;LEU A 259;SER A  22;PHE A 286;VAL A 280","NAI A 301 (-4.4A);NAI A 301 (-3.8A);None;None;None","1.49A","3nhxA-1o9bA:0.0","3nhxA-1o9bA:19.44"],["4AC9_C_DXCC1477_0","MJ0495-LIKE PROTEIN","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"THR A 137;GLY A 140;ILE A 151;LEU A  87","None","0.91A","4ac9C-1o9bA:3.6","4ac9C-1o9bA:19.80"],["4ACA_C_DXCC1477_0","TRANSLATION ELONGATION FACTOR SELB","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"THR A 137;GLY A 140;ILE A 151;LEU A  87","None","0.89A","4acaC-1o9bA:3.5","4acaC-1o9bA:19.80"],["4ACA_C_DXCC1478_0","TRANSLATION ELONGATION FACTOR SELB","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"GLY A 108;THR A 109;ILE A 112;THR A 175","None","0.95A","4acaC-1o9bA:3.4","4acaC-1o9bA:19.80"],["4ACB_C_DXCC1477_0","TRANSLATION ELONGATION FACTOR SELB","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"THR A 137;GLY A 140;ILE A 151;LEU A  87","None","0.91A","4acbC-1o9bA:3.1","4acbC-1o9bA:19.80"],["4EYR_B_RITB301_2","HIV-1 PROTEASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"ARG A 156;GLY A 134;ALA A 135;ASP A 107","NAI A 301 (-3.5A);NAI A 301 (-3.1A);NAI A 301 (-3.7A);PO4 A 302 (-3.0A)","0.76A","4eyrB-1o9bA:undetectable","4eyrB-1o9bA:18.55"],["4HB8_A_DXCA75_0","PPCA","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"ILE A 151;LEU A 129;ILE A 112;GLY A 134","None;None;None;NAI A 301 (-3.1A)","0.80A","4hb8A-1o9bA:undetectable","4hb8A-1o9bA:16.73"],["4QYN_B_RTLB201_0","RETINOL-BINDING PROTEIN 2","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"MET A 127;ILE A 151;THR A 204;LEU A 241;LEU A 200","None;None;NAI A 301 (-4.4A);None;None","1.06A","4qynB-1o9bA:undetectable","4qynB-1o9bA:19.31"],["4QZT_A_RTLA201_0","RETINOL-BINDING PROTEIN 2","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"MET A 127;ILE A 151;THR A 204;LEU A 241;LEU A 200","None;None;NAI A 301 (-4.4A);None;None","1.09A","4qztA-1o9bA:undetectable","4qztA-1o9bA:19.31"],["4QZT_A_RTLA201_1","RETINOL-BINDING PROTEIN 2","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",3,"PHE A 190;THR A 239;LEU A 223","None","0.79A","4qztA-1o9bA:undetectable","4qztA-1o9bA:19.31"],["4QZU_C_RTLC201_0","RETINOL-BINDING PROTEIN 2","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"MET A 127;ILE A 151;THR A 204;LEU A 241;LEU A 200","None;None;NAI A 301 (-4.4A);None;None","1.09A","4qzuC-1o9bA:undetectable","4qzuC-1o9bA:19.31"],["5BXN_H_BO2H301_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-3","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"THR A  93;GLN A  72;GLY A 103;ALA A  85;THR A  82","None;PO4 A 303 (-3.6A);None;None;None","1.19A","5bxnH-1o9bA:undetectable;5bxnI-1o9bA:undetectable","5bxnH-1o9bA:22.60;5bxnI-1o9bA:22.67"],["5NZX_A_9F2A1102_1","DNA CROSS-LINK REPAIR 1A PROTEIN","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"THR A  93;GLN A  26;ILE A  10;GLY A  65","None","0.98A","5nzxA-1o9bA:2.3","5nzxA-1o9bA:23.87"],["5NZY_A_CE3A1102_1","DNA CROSS-LINK REPAIR 1A PROTEIN","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",4,"THR A  93;GLN A  26;ILE A  10;GLY A  65","None","0.97A","5nzyA-1o9bA:2.2","5nzyA-1o9bA:23.87"],["5T2Z_B_017B201_1","PROTEASE;PROTEASE","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"LEU A 129;GLY A 143;ALA A 144;GLY A 124;ILE A 151","None","1.00A","5t2zA-1o9bA:undetectable","5t2zA-1o9bA:17.82"],["6BAA_E_GBME2001_2","ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",3,"LEU A  12;THR A 106;ASN A 105","None","0.58A","6baaE-1o9bA:undetectable","6baaE-1o9bA:10.48"],["6BAA_F_GBMF2001_2","ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",3,"LEU A  12;THR A 106;ASN A 105","None","0.57A","6baaF-1o9bA:undetectable","6baaF-1o9bA:10.48"],["6BAA_G_GBMG2001_2","ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",3,"LEU A  12;THR A 106;ASN A 105","None","0.58A","6baaG-1o9bA:undetectable","6baaG-1o9bA:10.48"],["6BAA_H_GBMH2001_2","ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",3,"LEU A  12;THR A 106;ASN A 105","None","0.58A","6baaH-1o9bA:undetectable","6baaH-1o9bA:10.48"],["6DLZ_A_CYZA1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"PRO A  23;SER A  20;ASP A 107;ILE A  10;GLY A  11","None;None;PO4 A 302 (-3.0A);None;None","1.42A","6dlzA-1o9bA:5.7;6dlzD-1o9bA:3.4","6dlzA-1o9bA:13.59;6dlzD-1o9bA:13.59"],["6DLZ_C_CYZC1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"ILE A  10;GLY A  11;PRO A  23;SER A  20;ASP A 107","None;None;None;None;PO4 A 302 (-3.0A)","1.42A","6dlzB-1o9bA:5.9;6dlzC-1o9bA:5.9","6dlzB-1o9bA:13.59;6dlzC-1o9bA:13.59"],["6DM1_A_CYZA1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"PRO A  23;SER A  20;ASP A 107;ILE A  10;GLY A  11","None;None;PO4 A 302 (-3.0A);None;None","1.42A","6dm1A-1o9bA:5.8;6dm1D-1o9bA:3.2","6dm1A-1o9bA:13.59;6dm1D-1o9bA:13.59"],["6DM1_C_CYZC1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"ILE A  10;GLY A  11;PRO A  23;SER A  20;ASP A 107","None;None;None;None;PO4 A 302 (-3.0A)","1.42A","6dm1B-1o9bA:4.6;6dm1C-1o9bA:2.3","6dm1B-1o9bA:13.59;6dm1C-1o9bA:13.59"],["6HUP_B_DZPB502_0","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3","1o9b","HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB","Escherichia coli",5,"ILE A  94;LEU A  56;LEU A  12;MET A  13;PHE A  42","None","1.43A","6hupA-1o9bA:0.0;6hupB-1o9bA:0.0","6hupA-1o9bA:18.29;6hupB-1o9bA:16.81"]]