SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1o9r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1o9r AGROBACTERIUM
TUMEFACIENS DPS
(Agrobacterium
tumefaciens) 		3 / 3 HIS A  52
ILE A 103
LEU A 110
 None
 0.72A 2kceA-1o9rA:
undetectable		 2kceA-1o9rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1o9r AGROBACTERIUM
TUMEFACIENS DPS
(Agrobacterium
tumefaciens) 		4 / 5 ARG A 113
ALA A 109
ASP A 108
GLU A 112
 None
 1.38A 2xrzA-1o9rA:
undetectable		 2xrzA-1o9rA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1o9r AGROBACTERIUM
TUMEFACIENS DPS
(Agrobacterium
tumefaciens) 		4 / 7 LEU A  62
ASP A 146
ALA A 143
TYR A 114
 None
 1.01A 3rodD-1o9rA:
undetectable		 3rodD-1o9rA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 1o9r AGROBACTERIUM
TUMEFACIENS DPS
(Agrobacterium
tumefaciens) 		5 / 9 GLY A 132
ALA A 131
ILE A 125
LEU A  22
VAL A  18
 None
 0.97A 3u7sB-1o9rA:
undetectable		 3u7sB-1o9rA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 1o9r AGROBACTERIUM
TUMEFACIENS DPS
(Agrobacterium
tumefaciens) 		4 / 5 LEU A  54
LEU A  43
PHE A  58
LEU A 110
 None
 1.02A 5gtrA-1o9rA:
undetectable		 5gtrA-1o9rA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 1o9r AGROBACTERIUM
TUMEFACIENS DPS
(Agrobacterium
tumefaciens) 		3 / 3 LEU A  62
LEU A 147
ARG A  72
 None
 0.56A 5hnzB-1o9rA:
undetectable		 5hnzB-1o9rA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1o9r AGROBACTERIUM
TUMEFACIENS DPS
(Agrobacterium
tumefaciens) 		5 / 10 ALA A 142
ILE A 121
ALA A 124
ILE A 125
ILE A  21
 None
 0.86A 5mvmD-1o9rA:
3.6
5mvmE-1o9rA:
3.6		 5mvmD-1o9rA:
15.53
5mvmE-1o9rA:
15.53