SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oa1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 8 ARG A 171
VAL A  62
LEU A  66
ALA A 162
 None
 0.90A 1fiqC-1oa1A:
undetectable		 1fiqC-1oa1A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 LEU A  66
GLU A 163
ILE A  41
GLY A  87
LEU A  34
 None
 1.20A 1g50B-1oa1A:
undetectable		 1g50B-1oa1A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 11 LEU A  66
GLU A 163
ILE A  41
GLY A  87
LEU A  34
 None
 1.19A 1g50C-1oa1A:
0.0		 1g50C-1oa1A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 ILE A 397
LEU A 484
PHE A 400
ILE A 468
LEU A 430
 None
 1.12A 1jolA-1oa1A:
undetectable		 1jolA-1oa1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 ILE A 397
LEU A 484
PHE A 400
ILE A 468
LEU A 430
 None
 1.14A 1jolB-1oa1A:
undetectable		 1jolB-1oa1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 VAL A 500
VAL A 402
LEU A 430
ALA A 466
 None
 0.84A 1pthA-1oa1A:
0.0		 1pthA-1oa1A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 VAL A 500
VAL A 402
LEU A 430
LEU A 504
 None
 0.80A 1pthA-1oa1A:
0.0		 1pthA-1oa1A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 VAL A 500
VAL A 402
LEU A 430
ALA A 466
 None
 0.84A 1pthB-1oa1A:
0.0		 1pthB-1oa1A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 VAL A 500
VAL A 402
LEU A 430
LEU A 504
 None
 0.79A 1pthB-1oa1A:
0.0		 1pthB-1oa1A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 ILE A 397
LEU A 484
PHE A 400
ILE A 468
LEU A 430
 None
 1.20A 1tdrA-1oa1A:
undetectable		 1tdrA-1oa1A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 5 LEU A  88
GLY A  87
ILE A  84
PHE A  36
 None
 0.88A 1xf1A-1oa1A:
undetectable		 1xf1A-1oa1A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 6 ARG A 171
VAL A  62
LEU A  66
ALA A 162
 None
 0.91A 2e1qA-1oa1A:
0.0		 2e1qA-1oa1A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 6 ARG A 171
VAL A  62
LEU A  66
ALA A 162
 None
 0.82A 2e1qC-1oa1A:
undetectable		 2e1qC-1oa1A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 6 TYR A 274
GLY A 457
TYR A 437
ASP A 461
 None
 1.16A 2g72A-1oa1A:
undetectable		 2g72A-1oa1A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		3 / 3 ALA A  97
GLY A  45
SER A  57
 None
 0.59A 2ivuA-1oa1A:
undetectable		 2ivuA-1oa1A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		3 / 3 ILE A 490
ILE A 536
LEU A 423
 None
 0.57A 2prgA-1oa1A:
undetectable		 2prgA-1oa1A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 ILE A 355
ALA A 358
GLY A 260
THR A 259
 None
 0.70A 2xrzB-1oa1A:
undetectable		 2xrzB-1oa1A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 8 LEU A 502
VAL A 526
LEU A 522
VAL A 529
 None
 0.66A 2zujA-1oa1A:
undetectable		 2zujA-1oa1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 ASN A 460
ALA A 377
ALA A 456
GLN A 458
 None
 0.88A 3a2qA-1oa1A:
undetectable		 3a2qA-1oa1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 8 ARG A 171
VAL A  62
LEU A  66
ALA A 162
 None
 1.00A 3ax7A-1oa1A:
0.0		 3ax7A-1oa1A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		3 / 3 SER A 352
GLN A 255
PHE A 351
 None
 0.63A 3g4lC-1oa1A:
0.5		 3g4lC-1oa1A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 VAL A 285
TYR A 264
LYS A 235
PRO A 364
 None
 1.11A 3hs4A-1oa1A:
undetectable		 3hs4A-1oa1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 5 ASN A  74
ALA A  68
ALA A  73
LYS A 496
 None
None
None
SF3  A1555 ( 4.5A)
 1.15A 3kp2B-1oa1A:
0.0		 3kp2B-1oa1A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 6 ILE A 367
PRO A 363
GLY A 234
VAL A 229
 None
None
None
GOL  A1556 ( 3.5A)
 0.86A 3n3iA-1oa1A:
undetectable		 3n3iA-1oa1A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 TYR A 437
GLY A 405
ALA A 491
ASP A 455
ALA A 432
 None
 1.15A 3nmuA-1oa1A:
1.8
3nmuF-1oa1A:
undetectable		 3nmuA-1oa1A:
21.81
3nmuF-1oa1A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 9 ILE A  41
THR A  69
ARG A 148
LEU A 151
GLY A 135
 None
 1.46A 3nxuB-1oa1A:
0.0		 3nxuB-1oa1A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 500
VAL A 402
LEU A 430
ALA A 466
LEU A 504
 None
 0.85A 3pghC-1oa1A:
undetectable		 3pghC-1oa1A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 10 ALA A  73
ILE A  84
ILE A 152
THR A  71
ILE A 136
 None
None
None
SF4  A1554 (-3.1A)
None
 1.25A 3prsA-1oa1A:
0.0		 3prsA-1oa1A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 ILE A 397
LEU A 484
PHE A 400
ILE A 468
LEU A 430
 None
 1.17A 3ql0A-1oa1A:
undetectable		 3ql0A-1oa1A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 9 ASN A  74
TYR A 334
GLY A 333
ASP A  76
LEU A 323
 None
 1.46A 3sfuB-1oa1A:
undetectable		 3sfuB-1oa1A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 ARG A 171
VAL A  62
LEU A  66
ALA A 162
 None
 0.99A 3uniA-1oa1A:
0.0		 3uniA-1oa1A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 8 GLY A 346
GLU A 251
TYR A 221
LEU A 168
VAL A 167
 None
 1.44A 4fgzA-1oa1A:
undetectable		 4fgzA-1oa1A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 5 VAL A 263
LEU A 252
ILE A 241
LEU A 240
 None
 0.84A 4mghA-1oa1A:
undetectable		 4mghA-1oa1A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 TYR A 437
ASN A 230
TYR A 288
GLU A 368
 None
 1.24A 4mi4A-1oa1A:
0.0
4mi4C-1oa1A:
0.0		 4mi4A-1oa1A:
15.08
4mi4C-1oa1A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 8 GLY A  45
ILE A  41
LEU A 180
LEU A 183
 None
 0.83A 4mwzB-1oa1A:
0.7		 4mwzB-1oa1A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 11 ILE A 397
LEU A 484
PHE A 400
ILE A 468
LEU A 430
 None
 1.17A 4qlfA-1oa1A:
undetectable		 4qlfA-1oa1A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 9 ALA A 404
ILE A 372
GLY A 457
ALA A 456
VAL A 453
 None
 1.26A 4r1zA-1oa1A:
1.2		 4r1zA-1oa1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 TYR A 161
ILE A 153
GLY A 154
ALA A 160
VAL A 498
 None
 1.05A 4rvdA-1oa1A:
undetectable		 4rvdA-1oa1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 PHE A  61
ILE A  41
GLY A  65
THR A  69
 None
 0.95A 4zdzA-1oa1A:
undetectable		 4zdzA-1oa1A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 PHE A  61
ILE A  41
GLY A  65
THR A  69
 None
 0.88A 4ze3A-1oa1A:
undetectable		 4ze3A-1oa1A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 ILE A 397
LEU A 484
PHE A 400
ILE A 468
LEU A 430
 None
 1.11A 5e8qB-1oa1A:
undetectable		 5e8qB-1oa1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 8 PHE A  61
ILE A  41
GLY A  65
THR A  69
 None
 0.94A 5esfA-1oa1A:
undetectable		 5esfA-1oa1A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 8 PHE A  61
ILE A  41
GLY A  65
THR A  69
 None
 0.89A 5esjA-1oa1A:
0.0		 5esjA-1oa1A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		3 / 3 ALA A 520
GLN A   5
THR A   9
 None
SF4  A1554 (-4.7A)
SF4  A1554 (-3.9A)
 0.72A 5n0oA-1oa1A:
undetectable		 5n0oA-1oa1A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 LEU A 465
ALA A 404
ILE A 512
LEU A 504
 None
 1.00A 5te8A-1oa1A:
0.0		 5te8A-1oa1A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 ILE A 397
LEU A 484
PHE A 400
ILE A 468
LEU A 430
 None
 1.11A 5ujxB-1oa1A:
undetectable		 5ujxB-1oa1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 12 PHE A  61
ILE A  41
PHE A 127
GLY A  65
THR A  69
 None
 1.33A 5v5zA-1oa1A:
undetectable		 5v5zA-1oa1A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 11 GLY A 515
GLY A 408
GLN A 410
GLU A   8
THR A   9
 None
None
None
None
SF4  A1554 (-3.9A)
 1.09A 5x1bG-1oa1A:
0.0
5x1bN-1oa1A:
0.0
5x1bO-1oa1A:
0.0		 5x1bG-1oa1A:
12.11
5x1bN-1oa1A:
25.04
5x1bO-1oa1A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 7 ALA A  68
PHE A  61
LEU A  38
ILE A 136
 None
 0.86A 6b5vA-1oa1A:
undetectable
6b5vB-1oa1A:
undetectable		 6b5vA-1oa1A:
9.04
6b5vB-1oa1A:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 10 ASN A  74
ARG A  79
ALA A  68
GLY A  65
ILE A  84
 None
 1.24A 6bniA-1oa1A:
undetectable		 6bniA-1oa1A:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		5 / 10 ASN A  74
ARG A  79
ALA A  68
GLY A  65
ILE A  84
 None
 1.25A 6bniB-1oa1A:
undetectable		 6bniB-1oa1A:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1oa1 HYDROXYLAMINE
REDUCTASE
(Desulfovibrio
vulgaris) 		4 / 6 ILE A  41
LEU A  38
ARG A  95
THR A 121
 None
 1.12A 6nmfN-1oa1A:
undetectable
6nmfW-1oa1A:
undetectable		 6nmfN-1oa1A:
25.04
6nmfW-1oa1A:
8.65