SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oa3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 1oa3 ENDO-BETA-1-4-GLUCAN
ASE
(Trichoderma
citrinoviride) 		3 / 3 TRP A 144
TYR A 178
LEU A 117
 None
 1.10A 1kxhA-1oa3A:
undetectable		 1kxhA-1oa3A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1oa3 ENDO-BETA-1-4-GLUCAN
ASE
(Trichoderma
citrinoviride) 		4 / 8 LEU A 208
ALA A  94
ILE A  92
GLY A 122
 None
None
None
NAG  A1220 ( 4.1A)
 0.79A 1sv9A-1oa3A:
undetectable		 1sv9A-1oa3A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1oa3 ENDO-BETA-1-4-GLUCAN
ASE
(Trichoderma
citrinoviride) 		3 / 3 TYR A 168
TYR A 195
GLY A 170
 None
 0.69A 3eteB-1oa3A:
undetectable
3eteD-1oa3A:
undetectable
3eteF-1oa3A:
undetectable		 3eteB-1oa3A:
18.99
3eteD-1oa3A:
18.99
3eteF-1oa3A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1oa3 ENDO-BETA-1-4-GLUCAN
ASE
(Trichoderma
citrinoviride) 		4 / 6 VAL A 172
ASN A 177
TYR A 195
ILE A  76
 None
 1.24A 3q5sA-1oa3A:
0.0		 3q5sA-1oa3A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 1oa3 ENDO-BETA-1-4-GLUCAN
ASE
(Trichoderma
citrinoviride) 		3 / 3 TYR A  98
GLN A 142
TRP A 120
 None
 1.03A 4kn2C-1oa3A:
0.0		 4kn2C-1oa3A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1oa3 ENDO-BETA-1-4-GLUCAN
ASE
(Trichoderma
citrinoviride) 		4 / 5 ALA A  83
TYR A 168
PRO A  80
PHE A 175
 None
 1.39A 4ze2A-1oa3A:
0.0		 4ze2A-1oa3A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 1oa3 ENDO-BETA-1-4-GLUCAN
ASE
(Trichoderma
citrinoviride) 		4 / 6 GLU A 116
PHE A 175
TYR A  60
PHE A 101
 None
 1.42A 5lrbA-1oa3A:
2.3		 5lrbA-1oa3A:
12.28