SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		3 / 3 ALA A 386
HIS A 387
VAL A 390
 None
 0.32A 1lqtB-1oahA:
undetectable		 1lqtB-1oahA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		3 / 3 ALA A 386
HIS A 387
VAL A 390
 None
 0.35A 1lquB-1oahA:
undetectable		 1lquB-1oahA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 8 HIS A 387
SER A 290
ARG A 412
TRP A 285
 None
 1.33A 1u1jA-1oahA:
undetectable		 1u1jA-1oahA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 7 GLY A 432
GLU A 428
SER A 430
HIS A 434
 None
None
None
HEM  A1523 (-3.2A)
 1.10A 2ackA-1oahA:
undetectable		 2ackA-1oahA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 7 TYR A 106
PHE A 108
PRO A 300
ALA A 427
 None
CL  A1527 (-4.6A)
None
None
 1.13A 2vcvA-1oahA:
0.5		 2vcvA-1oahA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 6 HIS A 434
GLU A 114
ASP A  67
GLU A  66
 HEM  A1523 (-3.2A)
CA  A1526 ( 3.4A)
None
None
 1.33A 3vywA-1oahA:
undetectable		 3vywA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		3 / 3 GLN A  96
ASP A 423
GLN A 419
 None
 0.86A 4aztA-1oahA:
undetectable		 4aztA-1oahA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 7 MET A 346
TYR A 360
GLU A 359
ARG A 364
 None
 1.49A 4r87J-1oahA:
undetectable
4r87L-1oahA:
undetectable		 4r87J-1oahA:
14.20
4r87L-1oahA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 4 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.43A 4w5oA-1oahA:
0.0		 4w5oA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 4 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.44A 4w5rA-1oahA:
0.0		 4w5rA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.40A 4w5tA-1oahA:
0.0		 4w5tA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 6 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.39A 4z4cA-1oahA:
undetectable		 4z4cA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.41A 4z4dA-1oahA:
undetectable		 4z4dA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 4 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.40A 4z4eA-1oahA:
0.0		 4z4eA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.36A 4z4hA-1oahA:
undetectable		 4z4hA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 4 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.34A 4z4iA-1oahA:
0.0		 4z4iA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.45A 5js1A-1oahA:
undetectable		 5js1A-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 6 HIS A 335
ASN A 190
VAL A 229
GLN A 232
 HEM  A1521 (-3.2A)
HEM  A1522 ( 4.1A)
None
HEM  A1522 ( 4.7A)
 1.30A 5xdhA-1oahA:
undetectable
5xdhC-1oahA:
undetectable		 5xdhA-1oahA:
10.16
5xdhC-1oahA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 6 GLN A 232
HIS A 335
ASN A 190
VAL A 229
 HEM  A1522 ( 4.7A)
HEM  A1521 (-3.2A)
HEM  A1522 ( 4.1A)
None
 1.29A 5xdhA-1oahA:
undetectable
5xdhC-1oahA:
undetectable		 5xdhA-1oahA:
10.16
5xdhC-1oahA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.46A 6cbdA-1oahA:
undetectable		 6cbdA-1oahA:
19.70