SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oai'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_1
(RETINOL-BINDING
PROTEIN 2)		 1oai NUCLEAR RNA EXPORT
FACTOR
(Homo
sapiens) 		3 / 3 LYS A 561
TRP A 594
GLN A 586
 None
 1.36A 4qzuC-1oaiA:
undetectable		 4qzuC-1oaiA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 1oai NUCLEAR RNA EXPORT
FACTOR
(Homo
sapiens) 		5 / 10 GLY A 610
ILE A 612
ALA A 608
THR A 604
HIS A 605
 None
 0.97A 6e5zA-1oaiA:
undetectable		 6e5zA-1oaiA:
15.22