SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oaz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 1oaz THIOREDOXIN 1
(Escherichia
coli) 		4 / 8 LEU A  24
ALA A  53
ILE A  59
VAL A  69
 None
 0.75A 1d4sB-1oazA:
undetectable		 1d4sB-1oazA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1oaz THIOREDOXIN 1
(Escherichia
coli) 		3 / 3 LYS A  50
ASP A  15
ASP A  26
 None
 0.92A 2br4D-1oazA:
undetectable		 2br4D-1oazA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1oaz THIOREDOXIN 1
(Escherichia
coli) 		5 / 12 LEU A 113
LEU A  56
ALA A 107
MET A  51
ALA A  53
 None
 1.10A 3b0wA-1oazA:
undetectable		 3b0wA-1oazA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1oaz THIOREDOXIN 1
(Escherichia
coli) 		4 / 8 LYS A  71
ASP A  26
LEU A 113
LEU A  92
 None
 0.96A 3lm8A-1oazA:
undetectable
3lm8C-1oazA:
undetectable		 3lm8A-1oazA:
24.07
3lm8C-1oazA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 1oaz THIOREDOXIN 1
(Escherichia
coli) 		4 / 5 GLY A  88
PRO A  90
TRP A  31
CYH A  32
 None
 1.33A 5nn8A-1oazA:
undetectable		 5nn8A-1oazA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 1oaz THIOREDOXIN 1
(Escherichia
coli) 		4 / 6 PRO A  34
TRP A  31
ILE A  74
GLY A  88
 None
 1.10A 6gqiA-1oazA:
undetectable		 6gqiA-1oazA:
12.73