SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ob1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1ob1 ANTIBODY, LIGHT
CHAIN
(Mus
musculus) 		4 / 8 GLY B  33
HIS B  53
THR B  52
ILE B  34
 None
 0.69A 1c9sU-1ob1B:
undetectable
1c9sV-1ob1B:
undetectable		 1c9sU-1ob1B:
12.50
1c9sV-1ob1B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1ob1 ANTIBODY, LIGHT
CHAIN
(Mus
musculus) 		4 / 8 GLY B  33
ALA B  24
THR B  52
ILE B  34
 None
 0.76A 1gtnA-1ob1B:
undetectable
1gtnB-1ob1B:
undetectable		 1gtnA-1ob1B:
12.50
1gtnB-1ob1B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1ob1 ANTIBODY, LIGHT
CHAIN
(Mus
musculus) 		4 / 8 GLY B  33
ALA B  24
THR B  52
ILE B  34
 None
 0.73A 1gtnP-1ob1B:
1.2
1gtnQ-1ob1B:
undetectable		 1gtnP-1ob1B:
12.50
1gtnQ-1ob1B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ob1 ANTIBODY, LIGHT
CHAIN
(Mus
musculus) 		4 / 8 GLY B  33
ALA B  24
THR B  52
ILE B  34
 None
 0.78A 1utdB-1ob1B:
1.5
1utdC-1ob1B:
undetectable		 1utdB-1ob1B:
12.50
1utdC-1ob1B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ob1 ANTIBODY, LIGHT
CHAIN
(Mus
musculus) 		4 / 8 GLY B  33
ALA B  24
THR B  52
ILE B  34
 None
 0.79A 1utdF-1ob1B:
undetectable
1utdG-1ob1B:
undetectable		 1utdF-1ob1B:
12.50
1utdG-1ob1B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ob1 ANTIBODY, LIGHT
CHAIN
(Mus
musculus) 		4 / 8 GLY B  33
ALA B  24
THR B  52
ILE B  34
 None
 0.79A 1utdJ-1ob1B:
undetectable
1utdK-1ob1B:
undetectable		 1utdJ-1ob1B:
12.50
1utdK-1ob1B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 1ob1 ANTIBODY, LIGHT
CHAIN
(Mus
musculus) 		5 / 12 VAL B 163
VAL B 181
SER B 179
ASN B 196
ASN B 155
 None
 1.38A 3nyaA-1ob1B:
undetectable		 3nyaA-1ob1B:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1ob1 ANTIBODY, LIGHT
CHAIN
(Mus
musculus) 		3 / 3 SER B 203
ALA B 198
VAL B 197
 None
 0.53A 5xiwC-1ob1B:
undetectable		 5xiwC-1ob1B:
18.48