SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1obf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 12 LEU O  17
HIS O  20
GLU O  22
GLY O  23
PHE O  56
 None
 1.46A 1d4fA-1obfO:
4.7		 1d4fA-1obfO:
22.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		6 / 7 SER O 153
THR O 155
ASN O 157
CYH O 158
TYR O 314
ASN O 316
 SO4  O 342 (-2.8A)
SO4  O 342 ( 4.4A)
None
None
None
None
 0.26A 1dssG-1obfO:
46.9		 1dssG-1obfO:
45.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		7 / 8 SER O 153
THR O 155
ASN O 157
CYH O 158
HIS O 181
TYR O 314
ASN O 316
 SO4  O 342 (-2.8A)
SO4  O 342 ( 4.4A)
None
None
None
None
None
 0.38A 1dssR-1obfO:
46.7		 1dssR-1obfO:
45.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		3 / 3 GLY O 227
ASP O 226
ASN O 230
 None
 0.52A 1vq1A-1obfO:
3.3		 1vq1A-1obfO:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 7 LEU O 159
GLY O 136
ILE O 274
PRO O 165
VAL O 163
 None
 1.48A 2aojB-1obfO:
undetectable		 2aojB-1obfO:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		4 / 5 LEU O 246
LEU O 263
CYH O 158
THR O 155
 None
None
None
SO4  O 342 ( 4.4A)
 1.31A 2oaxD-1obfO:
0.0		 2oaxD-1obfO:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		3 / 3 LEU O  17
TYR O  21
GLY O  24
 None
 0.61A 2ocuA-1obfO:
undetectable		 2ocuA-1obfO:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		4 / 7 VAL O   4
HIS O  20
THR O 328
LEU O 325
 None
 1.23A 3arrA-1obfO:
undetectable		 3arrA-1obfO:
22.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		7 / 8 SER O 153
THR O 155
ASN O 157
CYH O 158
HIS O 181
TYR O 314
ASN O 316
 SO4  O 342 (-2.8A)
SO4  O 342 ( 4.4A)
None
None
None
None
None
 0.34A 3dmtC-1obfO:
45.2		 3dmtC-1obfO:
47.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		4 / 5 ARG O  14
ASN O  15
HIS O  53
ALA O  52
 None
 1.13A 3frqA-1obfO:
undetectable		 3frqA-1obfO:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		4 / 7 ARG O  14
ASN O  15
HIS O  53
ALA O  52
 None
 1.14A 3frqB-1obfO:
undetectable		 3frqB-1obfO:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		3 / 3 ASN O  15
ASP O  50
ARG O 199
 None
None
SO4  O 341 (-3.4A)
 0.95A 3k13C-1obfO:
undetectable		 3k13C-1obfO:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		3 / 3 ASN O 240
ASP O 315
ASN O 316
 None
 0.70A 4agaA-1obfO:
undetectable		 4agaA-1obfO:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 11 SER O 122
ILE O  12
ASP O 315
GLY O 319
PHE O 320
 None
 1.35A 4fogA-1obfO:
0.0		 4fogA-1obfO:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 11 SER O 122
ILE O  12
ASP O 315
GLY O 319
PHE O 320
 None
 1.35A 4fogC-1obfO:
0.0		 4fogC-1obfO:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		4 / 7 LEU O 300
SER O 311
ILE O 243
VAL O 180
 None
 1.15A 4tvtA-1obfO:
0.0		 4tvtA-1obfO:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		4 / 6 GLU O  30
GLY O   8
ASP O  36
GLY O  13
 None
 0.95A 5cdpA-1obfO:
2.5
5cdpB-1obfO:
undetectable		 5cdpA-1obfO:
20.53
5cdpB-1obfO:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		3 / 3 THR O 156
ALA O 152
ASN O 157
 None
 0.59A 5ersA-1obfO:
2.0		 5ersA-1obfO:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 12 PRO O  86
THR O  99
PHE O 102
GLN O  84
ASN O  35
 None
 1.38A 5hgcA-1obfO:
undetectable		 5hgcA-1obfO:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 10 TYR O   9
ILE O 120
ILE O 149
HIS O  20
ILE O  29
 None
 1.39A 5vkqA-1obfO:
0.0
5vkqD-1obfO:
0.0		 5vkqA-1obfO:
12.42
5vkqD-1obfO:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 10 HIS O  20
ILE O  29
TYR O   9
ILE O 120
ILE O 149
 None
 1.40A 5vkqA-1obfO:
0.0
5vkqB-1obfO:
0.0		 5vkqA-1obfO:
12.42
5vkqB-1obfO:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 9 HIS O  20
ILE O  29
TYR O   9
ILE O 120
ILE O 149
 None
 1.40A 5vkqB-1obfO:
undetectable
5vkqC-1obfO:
undetectable		 5vkqB-1obfO:
12.42
5vkqC-1obfO:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		5 / 10 HIS O  20
ILE O  29
TYR O   9
ILE O 120
ILE O 149
 None
 1.39A 5vkqC-1obfO:
0.0
5vkqD-1obfO:
0.0		 5vkqC-1obfO:
12.42
5vkqD-1obfO:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Achromobacter
xylosoxidans) 		4 / 8 GLY O  13
ILE O  12
ASP O  50
HIS O  53
 None
 0.94A 6ag0A-1obfO:
undetectable		 6ag0A-1obfO:
11.64