SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1obp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DZM_A_BZMA600_0 (ODORANT-BINDING PROTEIN)	1obp	ODORANT-BINDING PROTEIN (Bos taurus)	4 / 8	ILE A 22 ASN A 87 ASN A 103 GLY A 117	UNX A 186 (-3.9A) UNX A 197 (-3.7A) UNX A 198 ( 2.8A) UNX A 181 (-2.9A)	0.36A	1dzmA-1obpA: 18.3	1dzmA-1obpA: 43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DZM_B_BZMB600_0 (ODORANT-BINDING PROTEIN)	1obp	ODORANT-BINDING PROTEIN (Bos taurus)	5 / 9	ILE A 22 TYR A 83 ASN A 87 ASN A 103 GLY A 117	UNX A 186 (-3.9A) UNX A 167 ( 4.6A) UNX A 197 (-3.7A) UNX A 198 ( 2.8A) UNX A 181 (-2.9A)	0.49A	1dzmB-1obpA: 18.6	1dzmB-1obpA: 43.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A83_A_DXCA1160_0 (MAJOR POLLEN ALLERGEN BET V 1-A)	1obp	ODORANT-BINDING PROTEIN (Bos taurus)	5 / 12	PHE A 40 PHE A 56 LEU A 10 ILE A 91 ALA A 71	UNX A 163 (-4.4A) UNX A 194 (-4.1A) None None UNX A 170 ( 4.0A)	1.36A	4a83A-1obpA: 2.3	4a83A-1obpA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1298_1 (GERANYLTRANSTRANSFER ASE)	1obp	ODORANT-BINDING PROTEIN (Bos taurus)	4 / 4	ILE A 91 PHE A 45 GLN A 8 ASP A 47	None	1.38A	4umjA-1obpA: undetectable	4umjA-1obpA: 18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HUO_D_08HD501_0 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOB UTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2)	1obp	ODORANT-BINDING PROTEIN (Bos taurus)	4 / 8	ASN A 103 PHE A 89 PHE A 40 VAL A 69	UNX A 198 ( 2.8A) UNX A 198 (-4.5A) UNX A 163 (-4.4A) None	1.23A	6huoC-1obpA: 1.0 6huoD-1obpA: undetectable	6huoC-1obpA: 23.49 6huoD-1obpA: 19.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DZM_A_BZMA600_0","ODORANT-BINDING PROTEIN","1obp","ODORANT-BINDING PROTEIN","Bos taurus",4,"ILE A  22;ASN A  87;ASN A 103;GLY A 117","UNX A 186 (-3.9A);UNX A 197 (-3.7A);UNX A 198 ( 2.8A);UNX A 181 (-2.9A)","0.36A","1dzmA-1obpA:18.3","1dzmA-1obpA:43.31"],["1DZM_B_BZMB600_0","ODORANT-BINDING PROTEIN","1obp","ODORANT-BINDING PROTEIN","Bos taurus",5,"ILE A  22;TYR A  83;ASN A  87;ASN A 103;GLY A 117","UNX A 186 (-3.9A);UNX A 167 ( 4.6A);UNX A 197 (-3.7A);UNX A 198 ( 2.8A);UNX A 181 (-2.9A)","0.49A","1dzmB-1obpA:18.6","1dzmB-1obpA:43.31"],["4A83_A_DXCA1160_0","MAJOR POLLEN ALLERGEN BET V 1-A","1obp","ODORANT-BINDING PROTEIN","Bos taurus",5,"PHE A  40;PHE A  56;LEU A  10;ILE A  91;ALA A  71","UNX A 163 (-4.4A);UNX A 194 (-4.1A);None;None;UNX A 170 ( 4.0A)","1.36A","4a83A-1obpA:2.3","4a83A-1obpA:21.18"],["4UMJ_A_BFQA1298_1","GERANYLTRANSTRANSFERASE","1obp","ODORANT-BINDING PROTEIN","Bos taurus",4,"ILE A  91;PHE A  45;GLN A   8;ASP A  47","None","1.38A","4umjA-1obpA:undetectable","4umjA-1obpA:18.68"],["6HUO_D_08HD501_0","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","1obp","ODORANT-BINDING PROTEIN","Bos taurus",4,"ASN A 103;PHE A  89;PHE A  40;VAL A  69","UNX A 198 ( 2.8A);UNX A 198 (-4.5A);UNX A 163 (-4.4A);None","1.23A","6huoC-1obpA:1.0;6huoD-1obpA:undetectable","6huoC-1obpA:23.49;6huoD-1obpA:19.35"]]