SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V1T_A_BEZA1274_0
(SYNTENIN 1)		 1oby SYNTENIN 1
(Homo
sapiens) 		4 / 4 HIS A 202
SER A 226
ARG A 229
ASN A 230
 SO4  A1272 (-3.9A)
SO4  A1272 (-2.7A)
SO4  A1272 (-3.9A)
SO4  A1272 (-3.1A)
 0.34A 1v1tA-1obyA:
13.2		 1v1tA-1obyA:
48.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W9E_A_BEZA1274_0
(SYNTENIN 1)		 1oby SYNTENIN 1
(Homo
sapiens) 		4 / 4 HIS A 202
SER A 226
ARG A 229
ASN A 230
 SO4  A1272 (-3.9A)
SO4  A1272 (-2.7A)
SO4  A1272 (-3.9A)
SO4  A1272 (-3.1A)
 0.46A 1w9eA-1obyA:
13.5		 1w9eA-1obyA:
48.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W9O_A_BEZA1274_0
(SYNTENIN 1)		 1oby SYNTENIN 1
(Homo
sapiens) 		4 / 4 HIS A 202
SER A 226
ARG A 229
ASN A 230
 SO4  A1272 (-3.9A)
SO4  A1272 (-2.7A)
SO4  A1272 (-3.9A)
SO4  A1272 (-3.1A)
 0.45A 1w9oA-1obyA:
13.2		 1w9oA-1obyA:
48.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W9Q_A_BEZA1274_0
(SYNTENIN 1)		 1oby SYNTENIN 1
(Homo
sapiens) 		4 / 4 HIS A 202
SER A 226
ARG A 229
ASN A 230
 SO4  A1272 (-3.9A)
SO4  A1272 (-2.7A)
SO4  A1272 (-3.9A)
SO4  A1272 (-3.1A)
 0.41A 1w9qA-1obyA:
13.4		 1w9qA-1obyA:
48.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1oby SYNTENIN 1
(Homo
sapiens) 		4 / 8 ILE A 269
GLY A 231
MET A 201
ILE A 221
 None
 0.72A 2qwxA-1obyA:
undetectable
2qwxB-1obyA:
undetectable		 2qwxA-1obyA:
16.82
2qwxB-1obyA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1oby SYNTENIN 1
(Homo
sapiens) 		4 / 8 ILE A 269
GLY A 231
MET A 201
ILE A 221
 None
 0.73A 4qogA-1obyA:
undetectable
4qogB-1obyA:
undetectable		 4qogA-1obyA:
16.82
4qogB-1obyA:
16.82