SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE
(Streptococcus
suis) 		3 / 3 LYS A 333
ASP A 279
ASN A 208
 None
 1.08A 2bm9A-1oc2A:
5.3		 2bm9A-1oc2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE
(Streptococcus
suis) 		3 / 3 ASP A 279
ASP A 276
ASN A 208
 None
 0.85A 2bm9D-1oc2A:
4.5		 2bm9D-1oc2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE
(Streptococcus
suis) 		3 / 3 LYS A 333
ASP A 279
ASP A 276
 None
 0.79A 2br4A-1oc2A:
4.8		 2br4A-1oc2A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE
(Streptococcus
suis) 		3 / 3 SER A 159
ASP A 288
ASN A 223
 None
None
TDX  A1349 (-4.6A)
 0.86A 3lslA-1oc2A:
undetectable
3lslD-1oc2A:
undetectable		 3lslA-1oc2A:
21.58
3lslD-1oc2A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE
(Streptococcus
suis) 		3 / 3 HIS A 121
SER A 168
ASN A 187
 None
 0.85A 3s8pB-1oc2A:
undetectable		 3s8pB-1oc2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE
(Streptococcus
suis) 		3 / 3 HIS A 121
SER A 168
ASN A 187
 None
 0.86A 5cprB-1oc2A:
0.0		 5cprB-1oc2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE
(Streptococcus
suis) 		4 / 8 TYR A  82
PHE A  20
ILE A 240
ILE A 228
 None
 0.96A 5hw8H-1oc2A:
undetectable		 5hw8H-1oc2A:
16.28