SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ocm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
6 / 12 GLY A 142
ALA A 141
GLY A 164
PRO A 128
THR A 118
VAL A  36
None
1.18A 1k6cB-1ocmA:
undetectable
1k6cB-1ocmA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 ILE A 168
GLY A 203
ALA A  99
MET A 207
GLY A 194
None
1.07A 1kiaA-1ocmA:
undetectable
1kiaA-1ocmA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 ILE A 168
GLY A 203
ALA A  99
MET A 207
GLY A 194
None
1.06A 1kiaB-1ocmA:
undetectable
1kiaB-1ocmA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 ILE A 168
GLY A 203
ALA A  99
MET A 207
GLY A 194
None
1.07A 1kiaC-1ocmA:
undetectable
1kiaC-1ocmA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 ILE A 168
GLY A 203
ALA A  99
MET A 207
GLY A 194
None
1.04A 1nbhB-1ocmA:
undetectable
1nbhB-1ocmA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 7 ALA A  38
ILE A 144
ILE A  29
GLU A  33
None
0.91A 1oniD-1ocmA:
0.0
1oniF-1ocmA:
undetectable
1oniD-1ocmA:
16.63
1oniF-1ocmA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 155
GLY A 149
VAL A 190
SER A 132
ILE A  65
POP  A1155 (-1.5A)
None
None
None
None
1.10A 1pk9C-1ocmA:
undetectable
1pk9C-1ocmA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 ALA A 147
ILE A 168
PRO A 159
LEU A  94
VAL A  90
None
1.06A 1rv7A-1ocmA:
0.0
1rv7B-1ocmA:
0.0
1rv7A-1ocmA:
13.79
1rv7B-1ocmA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 8 ASP A 188
SER A 184
TYR A 183
HIS A 273
None
1.34A 2bteD-1ocmA:
undetectable
2bteD-1ocmA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A  25
ALA A  28
ALA A  48
GLY A  56
ALA A  58
None
1.11A 2f16H-1ocmA:
undetectable
2f16I-1ocmA:
undetectable
2f16H-1ocmA:
18.81
2f16I-1ocmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A  25
ALA A  28
ALA A  48
GLY A  56
ALA A  58
None
1.11A 2f16V-1ocmA:
undetectable
2f16W-1ocmA:
undetectable
2f16V-1ocmA:
18.81
2f16W-1ocmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 HIS A  42
PHE A  39
PRO A 145
LEU A  94
ILE A 101
None
1.39A 2fj1A-1ocmA:
undetectable
2fj1A-1ocmA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
3 / 3 ARG A 319
ARG A 323
ARG A 320
None
1.18A 2jb7A-1ocmA:
undetectable
2jb7B-1ocmA:
undetectable
2jb7C-1ocmA:
undetectable
2jb7A-1ocmA:
18.50
2jb7B-1ocmA:
18.50
2jb7C-1ocmA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
3 / 3 ARG A 320
ARG A 319
ARG A 323
None
1.21A 2jb7A-1ocmA:
undetectable
2jb7B-1ocmA:
undetectable
2jb7C-1ocmA:
undetectable
2jb7A-1ocmA:
18.50
2jb7B-1ocmA:
18.50
2jb7C-1ocmA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
3 / 3 ARG A 323
ARG A 320
ARG A 319
None
1.14A 2jb7A-1ocmA:
undetectable
2jb7B-1ocmA:
undetectable
2jb7C-1ocmA:
undetectable
2jb7A-1ocmA:
18.50
2jb7B-1ocmA:
18.50
2jb7C-1ocmA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 THR A 165
ALA A 147
ALA A  38
THR A 118
GLY A 130
None
None
None
None
POP  A1155 ( 4.9A)
1.03A 2ve3A-1ocmA:
0.0
2ve3A-1ocmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 THR A 165
ALA A 147
ALA A  38
THR A 118
GLY A 130
None
None
None
None
POP  A1155 ( 4.9A)
1.01A 2ve3B-1ocmA:
undetectable
2ve3B-1ocmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
3 / 3 PRO A 349
GLY A 357
TYR A 162
None
0.51A 2vouA-1ocmA:
undetectable
2vouA-1ocmA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
3 / 3 PRO A 349
GLY A 357
TYR A 162
None
0.51A 2vouB-1ocmA:
0.0
2vouB-1ocmA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
3 / 3 PRO A 349
GLY A 357
TYR A 162
None
0.51A 2vouC-1ocmA:
0.0
2vouC-1ocmA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 6 THR A 105
MET A  70
LYS A  44
ILE A 101
None
1.35A 2w98B-1ocmA:
undetectable
2w98B-1ocmA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 PHE A  39
HIS A  42
ALA A  48
LEU A   7
ILE A 144
None
1.27A 2xkwB-1ocmA:
undetectable
2xkwB-1ocmA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 10 GLU A 407
GLY A 194
LEU A 175
ILE A 168
MET A 207
None
1.39A 3adsA-1ocmA:
undetectable
3adsA-1ocmA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 ALA A 167
PHE A 193
ALA A 136
TYR A 162
GLN A 151
None
1.30A 3bszF-1ocmA:
0.0
3bszF-1ocmA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 4 PHE A  39
LYS A 104
ILE A  29
THR A 118
None
1.47A 3ia4B-1ocmA:
undetectable
3ia4B-1ocmA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 GLY A 215
PHE A 213
SER A 211
ALA A 201
ILE A 216
None
1.14A 3id6C-1ocmA:
undetectable
3id6C-1ocmA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 8 LEU A 146
VAL A 190
ILE A  65
VAL A  90
LEU A  94
None
1.39A 3kp6A-1ocmA:
undetectable
3kp6B-1ocmA:
undetectable
3kp6A-1ocmA:
15.00
3kp6B-1ocmA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 6 ILE A  61
VAL A  59
LEU A 146
LEU A 192
None
0.85A 3kp6A-1ocmA:
undetectable
3kp6B-1ocmA:
undetectable
3kp6A-1ocmA:
15.00
3kp6B-1ocmA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 10 GLY A 203
PHE A 213
LEU A 200
LEU A 192
ILE A 168
None
1.26A 3kvrA-1ocmA:
undetectable
3kvrA-1ocmA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 10 ILE A 157
PHE A 213
ALA A 401
LEU A 400
ALA A 201
None
1.20A 3lw5B-1ocmA:
0.0
3lw5B-1ocmA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A  25
ALA A  28
ALA A  48
GLY A  56
ALA A  58
None
1.10A 3mg0V-1ocmA:
undetectable
3mg0W-1ocmA:
undetectable
3mg0V-1ocmA:
18.81
3mg0W-1ocmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 7 ILE A  57
LEU A   4
LEU A 200
VAL A 156
SER A 132
None
1.35A 3r9vA-1ocmA:
undetectable
3r9vB-1ocmA:
undetectable
3r9vA-1ocmA:
19.81
3r9vB-1ocmA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 7 THR A 165
HIS A 122
ASN A 120
PHE A 193
None
1.36A 4awuA-1ocmA:
undetectable
4awuA-1ocmA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 LEU A 400
GLY A 194
GLY A 140
ASP A 199
GLY A 191
None
1.09A 4blvA-1ocmA:
undetectable
4blvA-1ocmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 5 PHE A  39
ILE A 102
GLY A  60
THR A 105
None
0.94A 4ejjC-1ocmA:
undetectable
4ejjC-1ocmA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 GLY A 346
GLU A 236
ALA A 238
ASN A 123
ASN A 120
None
1.17A 4pb1A-1ocmA:
undetectable
4pb1A-1ocmA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 4qvmV-1ocmA:
undetectable
4qvmb-1ocmA:
undetectable
4qvmV-1ocmA:
19.76
4qvmb-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 4qvmH-1ocmA:
undetectable
4qvmN-1ocmA:
undetectable
4qvmH-1ocmA:
19.76
4qvmN-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 4qvpV-1ocmA:
undetectable
4qvpb-1ocmA:
undetectable
4qvpV-1ocmA:
19.76
4qvpb-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.35A 4qvpH-1ocmA:
undetectable
4qvpN-1ocmA:
undetectable
4qvpH-1ocmA:
19.76
4qvpN-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 4qvqV-1ocmA:
undetectable
4qvqb-1ocmA:
undetectable
4qvqV-1ocmA:
19.76
4qvqb-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 4qvqH-1ocmA:
undetectable
4qvqN-1ocmA:
undetectable
4qvqH-1ocmA:
19.76
4qvqN-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 10 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.35A 4qvvV-1ocmA:
undetectable
4qvvb-1ocmA:
undetectable
4qvvV-1ocmA:
19.76
4qvvb-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 10 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 4qvvH-1ocmA:
0.0
4qvvN-1ocmA:
undetectable
4qvvH-1ocmA:
19.76
4qvvN-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.35A 4qvwV-1ocmA:
undetectable
4qvwb-1ocmA:
undetectable
4qvwV-1ocmA:
19.76
4qvwb-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.35A 4qvwH-1ocmA:
undetectable
4qvwN-1ocmA:
undetectable
4qvwH-1ocmA:
19.76
4qvwN-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.33A 4qvyV-1ocmA:
0.0
4qvyb-1ocmA:
undetectable
4qvyV-1ocmA:
19.76
4qvyb-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.34A 4qvyH-1ocmA:
0.0
4qvyN-1ocmA:
undetectable
4qvyH-1ocmA:
19.76
4qvyN-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.35A 4qw0V-1ocmA:
undetectable
4qw0b-1ocmA:
undetectable
4qw0V-1ocmA:
19.76
4qw0b-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 4qw0H-1ocmA:
undetectable
4qw0N-1ocmA:
undetectable
4qw0H-1ocmA:
19.76
4qw0N-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 4qw1H-1ocmA:
undetectable
4qw1N-1ocmA:
undetectable
4qw1H-1ocmA:
19.76
4qw1N-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.37A 4qw3V-1ocmA:
undetectable
4qw3b-1ocmA:
undetectable
4qw3V-1ocmA:
19.76
4qw3b-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.37A 4qw3H-1ocmA:
undetectable
4qw3N-1ocmA:
undetectable
4qw3H-1ocmA:
19.76
4qw3N-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 8 ALA A 197
ALA A 201
ALA A 397
ALA A 399
ALA A 403
None
1.43A 4twdF-1ocmA:
0.0
4twdG-1ocmA:
0.0
4twdH-1ocmA:
0.0
4twdI-1ocmA:
0.0
4twdJ-1ocmA:
0.0
4twdF-1ocmA:
22.14
4twdG-1ocmA:
22.14
4twdH-1ocmA:
22.14
4twdI-1ocmA:
22.14
4twdJ-1ocmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 6 TYR A 342
GLU A 230
LEU A 364
PHE A 231
None
1.29A 4twdF-1ocmA:
0.0
4twdG-1ocmA:
0.0
4twdF-1ocmA:
22.14
4twdG-1ocmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 6 TYR A 342
GLU A 230
LEU A 364
PHE A 231
None
1.18A 4twdI-1ocmA:
0.0
4twdJ-1ocmA:
0.0
4twdI-1ocmA:
22.14
4twdJ-1ocmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 9 TYR A 183
THR A 152
GLY A 130
THR A 356
LEU A 300
None
POP  A1155 (-4.5A)
POP  A1155 ( 4.9A)
None
None
1.33A 4ze0A-1ocmA:
undetectable
4ze0A-1ocmA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 7 ALA A 137
ASP A  63
ARG A  41
GLY A 103
None
0.91A 5bs8A-1ocmA:
undetectable
5bs8C-1ocmA:
undetectable
5bs8D-1ocmA:
undetectable
5bs8A-1ocmA:
24.80
5bs8C-1ocmA:
24.80
5bs8D-1ocmA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 9 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.34A 5cz7V-1ocmA:
0.0
5cz7b-1ocmA:
undetectable
5cz7V-1ocmA:
19.76
5cz7b-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.35A 5cz7H-1ocmA:
undetectable
5cz7N-1ocmA:
undetectable
5cz7H-1ocmA:
19.76
5cz7N-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.35A 5d0xV-1ocmA:
undetectable
5d0xb-1ocmA:
undetectable
5d0xV-1ocmA:
19.76
5d0xb-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.36A 5d0xH-1ocmA:
undetectable
5d0xN-1ocmA:
undetectable
5d0xH-1ocmA:
19.76
5d0xN-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
3 / 3 PRO A 115
LEU A 119
SER A 355
None
0.84A 5fsaB-1ocmA:
undetectable
5fsaB-1ocmA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 ALA A 136
GLY A 134
GLY A 149
GLY A 140
LEU A 200
None
1.10A 5gwxA-1ocmA:
undetectable
5gwxA-1ocmA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 155
GLY A 149
VAL A 190
SER A 132
ILE A  65
POP  A1155 (-1.5A)
None
None
None
None
1.11A 5i3cC-1ocmA:
undetectable
5i3cC-1ocmA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.37A 5l5fV-1ocmA:
0.0
5l5fb-1ocmA:
0.0
5l5fV-1ocmA:
19.76
5l5fb-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.38A 5l5fH-1ocmA:
0.0
5l5fN-1ocmA:
undetectable
5l5fH-1ocmA:
19.76
5l5fN-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 SER A 127
THR A 108
THR A 107
THR A 106
ARG A 158
None
None
None
None
POP  A1155 (-3.1A)
1.40A 5l66V-1ocmA:
undetectable
5l66b-1ocmA:
undetectable
5l66V-1ocmA:
19.76
5l66b-1ocmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 SER A 135
GLN A 388
THR A 105
GLY A 149
THR A 150
None
1.26A 5oj0A-1ocmA:
undetectable
5oj0A-1ocmA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 VAL A 389
LEU A 204
ASP A 396
ALA A 403
PRO A 376
None
1.32A 5syfB-1ocmA:
undetectable
5syfB-1ocmA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 GLY A 322
GLY A 325
ALA A 265
ILE A 276
LEU A 367
None
1.17A 6b3bA-1ocmA:
undetectable
6b3bA-1ocmA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 VAL A  40
ILE A 157
GLY A 191
ALA A 136
ALA A 160
None
1.04A 6c2mD-1ocmA:
undetectable
6c2mD-1ocmA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 6 ARG A 113
PRO A 274
GLN A 277
ARG A 363
POP  A1155 (-4.0A)
None
POP  A1155 ( 4.7A)
None
1.45A 6ef6A-1ocmA:
0.0
6ef6A-1ocmA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 7 VAL A  90
ILE A 101
GLY A 142
ALA A 147
None
0.90A 6hd6B-1ocmA:
undetectable
6hd6B-1ocmA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 12 ALA A  28
ALA A  48
GLY A  56
ALA A  58
THR A 100
None
1.02A 6hwdH-1ocmA:
undetectable
6hwdI-1ocmA:
undetectable
6hwdH-1ocmA:
10.00
6hwdI-1ocmA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
5 / 11 ALA A  28
ALA A  48
GLY A  56
ALA A  58
THR A 100
None
1.02A 6hwdV-1ocmA:
undetectable
6hwdV-1ocmA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)
1ocm MALONAMIDASE E2
(Bradyrhizobium
japonicum)
4 / 4 ASP A   6
ILE A  11
PRO A  18
LEU A   7
None
1.44A 6mkeA-1ocmA:
0.0
6mkeA-1ocmA:
14.84