SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ocs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 1ocs SORTING NEXIN GRD19
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  68
LEU A 143
GLY A 147
LEU A 151
 None
 0.84A 1gtiA-1ocsA:
undetectable		 1gtiA-1ocsA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 1ocs SORTING NEXIN GRD19
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  68
LEU A 143
GLY A 147
LEU A 151
 None
 0.91A 1gtiB-1ocsA:
0.0		 1gtiB-1ocsA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1ocs SORTING NEXIN GRD19
(Saccharomyces
cerevisiae) 		3 / 3 ILE A  38
ILE A  62
THR A  66
 None
 0.57A 1rg7A-1ocsA:
undetectable		 1rg7A-1ocsA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1ocs SORTING NEXIN GRD19
(Saccharomyces
cerevisiae) 		4 / 6 GLU A  33
ASN A  67
PRO A  32
ALA A  30
 None
 1.40A 2ejfB-1ocsA:
undetectable		 2ejfB-1ocsA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1ocs SORTING NEXIN GRD19
(Saccharomyces
cerevisiae) 		4 / 7 GLU A  33
ASN A  67
PRO A  32
ALA A  30
 None
 1.46A 2ejgB-1ocsA:
undetectable		 2ejgB-1ocsA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ocs SORTING NEXIN GRD19
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 154
LEU A 131
VAL A  40
ASP A  84
 None
None
None
GOL  A1163 (-3.3A)
 1.11A 4l4cA-1ocsA:
0.0		 4l4cA-1ocsA:
18.18