SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ocx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1ocx MALTOSE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 8 LEU A 126
PRO A 129
TYR A  14
GLU A  12
 None
 1.15A 1jtvA-1ocxA:
undetectable		 1jtvA-1ocxA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1ocx MALTOSE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 5 THR A 149
GLY A 151
VAL A 154
PRO A 167
 None
 1.17A 4grkA-1ocxA:
undetectable		 4grkA-1ocxA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1ocx MALTOSE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 8 ASN A  83
PRO A 104
PHE A  81
TYR A  35
 None
 1.17A 5amkA-1ocxA:
undetectable		 5amkA-1ocxA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1ocx MALTOSE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 8 ILE A  49
VAL A  91
ILE A  94
ILE A 108
PHE A  66
 None
 1.43A 5hi2A-1ocxA:
undetectable		 5hi2A-1ocxA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1ocx MALTOSE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		3 / 3 MET A   8
ASP A  90
ARG A  27
 None
 1.05A 5z6jA-1ocxA:
undetectable		 5z6jA-1ocxA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1ocx MALTOSE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 11 THR A 149
GLY A 133
ILE A  96
ILE A 108
ILE A 144
 None
 1.07A 6ebzB-1ocxA:
undetectable		 6ebzB-1ocxA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1ocx MALTOSE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 11 THR A 149
GLY A 133
ILE A  96
ILE A 108
ILE A 144
 None
 1.06A 6ebzC-1ocxA:
undetectable		 6ebzC-1ocxA:
17.79