SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1od6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 VAL A 146
LEU A 145
GLY A 140
ALA A 136
LEU A 154
 None
 1.04A 2aylA-1od6A:
undetectable		 2aylA-1od6A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 VAL A 146
LEU A 145
GLY A 140
ALA A 136
LEU A 154
 None
 1.05A 3n8zA-1od6A:
undetectable		 3n8zA-1od6A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 VAL A 146
LEU A 145
GLY A 140
ALA A 136
LEU A 154
 None
 1.07A 3n8zB-1od6A:
undetectable		 3n8zB-1od6A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 THR A 150
LEU A  45
VAL A 142
VAL A 146
 None
 0.95A 4cp4A-1od6A:
undetectable		 4cp4A-1od6A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 8 THR A  31
ALA A  33
LEU A  35
VAL A   4
 None
None
PNS  A1161 (-3.7A)
None
 0.73A 4iizB-1od6A:
undetectable		 4iizB-1od6A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 VAL A  32
ALA A  33
TYR A   5
GLY A   7
THR A  59
 None
None
None
PNS  A1161 (-3.6A)
None
 1.26A 4mm4A-1od6A:
undetectable		 4mm4A-1od6A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 THR A  31
ALA A  33
LEU A  35
SER A   8
 None
None
PNS  A1161 (-3.7A)
PNS  A1161 (-3.0A)
 0.77A 4pwjA-1od6A:
undetectable		 4pwjA-1od6A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 THR A  31
ALA A  33
LEU A  35
SER A   8
 None
None
PNS  A1161 (-3.7A)
PNS  A1161 (-3.0A)
 0.79A 4pwjB-1od6A:
undetectable		 4pwjB-1od6A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		5 / 9 VAL A 146
LEU A 145
GLY A 140
ALA A 136
LEU A 154
 None
 1.08A 4rs0A-1od6A:
undetectable		 4rs0A-1od6A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 THR A  31
ALA A  33
LEU A  35
SER A   8
 None
None
PNS  A1161 (-3.7A)
PNS  A1161 (-3.0A)
 0.80A 5bojB-1od6A:
undetectable		 5bojB-1od6A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 VAL A 146
LEU A 145
GLY A 140
ALA A 136
LEU A 154
 None
 1.11A 5ikrA-1od6A:
undetectable		 5ikrA-1od6A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 HIS A   2
VAL A  78
TYR A 110
GLN A  84
 None
None
SO4  A1164 (-4.1A)
None
 1.29A 5kkzA-1od6A:
undetectable
5kkzG-1od6A:
0.0		 5kkzA-1od6A:
19.05
5kkzG-1od6A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 HIS A   2
VAL A  78
TYR A 110
GLN A  84
 None
None
SO4  A1164 (-4.1A)
None
 1.29A 5kkzC-1od6A:
0.0
5kkzE-1od6A:
undetectable		 5kkzC-1od6A:
24.14
5kkzE-1od6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 HIS A   2
VAL A  78
TYR A 110
GLN A  84
 None
None
SO4  A1164 (-4.1A)
None
 1.24A 5kkzM-1od6A:
undetectable
5kkzO-1od6A:
undetectable		 5kkzM-1od6A:
24.14
5kkzO-1od6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 TYR A  44
SER A  47
ALA A  48
THR A  69
 None
 1.18A 5n0tA-1od6A:
undetectable		 5n0tA-1od6A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 TYR A  44
SER A  47
ALA A  48
THR A  69
 None
 1.14A 5n0wB-1od6A:
undetectable		 5n0wB-1od6A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		3 / 3 SER A  47
ALA A  48
THR A  69
 None
 0.73A 5n0xB-1od6A:
undetectable		 5n0xB-1od6A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		3 / 3 GLU A  50
ASP A  10
PRO A  11
 None
 0.76A 6berA-1od6A:
undetectable		 6berA-1od6A:
7.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 GLY A   7
HIS A  16
SER A 128
SER A 129
 PNS  A1161 (-3.6A)
SO4  A1163 (-4.1A)
None
SO4  A1163 (-3.3A)
 0.31A 6jmjA-1od6A:
24.6		 6jmjA-1od6A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		6 / 7 GLY A   7
PHE A   9
HIS A  16
ARG A  91
SER A 128
SER A 129
 PNS  A1161 (-3.6A)
None
SO4  A1163 (-4.1A)
SO4  A1163 (-3.7A)
None
SO4  A1163 (-3.3A)
 0.64A 6jnhA-1od6A:
24.8		 6jnhA-1od6A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 GLY A   7
ARG A  91
SER A 128
SER A 129
 PNS  A1161 (-3.6A)
SO4  A1163 (-3.7A)
None
SO4  A1163 (-3.3A)
 0.71A 6jogA-1od6A:
24.6		 6jogA-1od6A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 GLY A   7
HIS A  16
SER A 128
SER A 129
 PNS  A1161 (-3.6A)
SO4  A1163 (-4.1A)
None
SO4  A1163 (-3.3A)
 0.35A 6jogA-1od6A:
24.6		 6jogA-1od6A:
49.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 HIS A  16
THR A  13
ARG A  22
ASP A  18
 SO4  A1163 (-4.1A)
SO4  A1163 ( 4.5A)
SO4  A1162 ( 4.2A)
None
 1.12A 6mn4E-1od6A:
undetectable		 6mn4E-1od6A:
23.11