SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ode'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 1ode CHORISMATE MUTASE
(Thermus
thermophilus) 		5 / 9 LEU A  72
PHE A  47
ALA A  92
LEU A  31
LEU A  27
 None
 1.09A 1nr6A-1odeA:
undetectable		 1nr6A-1odeA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1ode CHORISMATE MUTASE
(Thermus
thermophilus) 		5 / 12 LEU A  28
LEU A  31
ASN A  34
ALA A  92
VAL A  90
 None
 1.11A 1sa1A-1odeA:
undetectable
1sa1B-1odeA:
undetectable		 1sa1A-1odeA:
14.74
1sa1B-1odeA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1ode CHORISMATE MUTASE
(Thermus
thermophilus) 		5 / 12 VAL A 103
LEU A  28
LEU A  31
ASN A  34
ALA A  92
 None
 0.98A 1sa1A-1odeA:
undetectable
1sa1B-1odeA:
undetectable		 1sa1A-1odeA:
14.74
1sa1B-1odeA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1ode CHORISMATE MUTASE
(Thermus
thermophilus) 		5 / 12 LEU A  28
LEU A  31
ASN A  34
ALA A  92
VAL A  90
 None
 1.11A 1sa1C-1odeA:
undetectable
1sa1D-1odeA:
undetectable		 1sa1C-1odeA:
14.74
1sa1D-1odeA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1ode CHORISMATE MUTASE
(Thermus
thermophilus) 		5 / 12 VAL A 103
LEU A  28
LEU A  31
ASN A  34
ALA A  92
 None
 1.00A 1sa1C-1odeA:
undetectable
1sa1D-1odeA:
undetectable		 1sa1C-1odeA:
14.74
1sa1D-1odeA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1ode CHORISMATE MUTASE
(Thermus
thermophilus) 		3 / 3 HIS A  20
ILE A  88
LEU A  27
 None
 0.66A 2kceA-1odeA:
undetectable		 2kceA-1odeA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 1ode CHORISMATE MUTASE
(Thermus
thermophilus) 		4 / 7 GLU A  40
ASN A  95
TRP A  94
ILE A  36
 None
 1.18A 4ii8A-1odeA:
undetectable		 4ii8A-1odeA:
22.22