SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1odf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 8 HIS A  54
TYR A  59
LEU A  55
GLU A  14
 None
 0.93A 1i7zA-1odfA:
undetectable		 1i7zA-1odfA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 9 GLY A 160
ILE A 207
THR A 284
ILE A 275
VAL A 281
 None
None
GOL  A 504 (-4.0A)
None
None
 1.32A 2nnhB-1odfA:
undetectable		 2nnhB-1odfA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 256
PHE A 259
LEU A  98
PRO A  99
VAL A 185
 None
 1.20A 2qd4B-1odfA:
undetectable		 2qd4B-1odfA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 4 PHE A  36
LYS A  44
ILE A  51
THR A 270
 None
SO4  A 501 (-3.5A)
None
None
 1.44A 3ia4B-1odfA:
1.7		 3ia4B-1odfA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 TYR A  67
ASP A  72
ASP A 132
 None
 0.94A 3ou6B-1odfA:
undetectable		 3ou6B-1odfA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 6 GLU A 159
ASP A  72
TYR A  74
LYS A 130
 None
None
SO4  A 502 (-4.6A)
None
 1.39A 3pocB-1odfA:
0.0		 3pocB-1odfA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 269
GLY A 266
LEU A  32
LEU A 265
ILE A  34
 None
 1.09A 3wdmD-1odfA:
undetectable		 3wdmD-1odfA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  83
LEU A  75
MET A 104
GLY A  97
LEU A  93
 None
 0.99A 4lmnA-1odfA:
undetectable		 4lmnA-1odfA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 274
SER A 283
ASN A 280
GLY A  43
ASN A 216
 None
None
None
SO4  A 501 (-3.2A)
None
 0.98A 4obwC-1odfA:
3.3		 4obwC-1odfA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 195
LEU A 196
GLU A 109
LEU A 111
 None
None
None
GOL  A 505 (-4.6A)
 0.78A 4wg0L-1odfA:
undetectable
4wg0M-1odfA:
undetectable		 4wg0L-1odfA:
3.83
4wg0M-1odfA:
3.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  15
LEU A  16
GLY A 206
SER A 204
LEU A  32
 None
 1.39A 4zbrA-1odfA:
undetectable		 4zbrA-1odfA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 ALA A  68
ASP A 103
THR A  76
GLN A  80
PHE A  73
 None
 1.33A 5hfjH-1odfA:
undetectable		 5hfjH-1odfA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 5 GLY A 146
THR A 145
GLY A 164
LEU A 107
 None
 0.81A 5jlcA-1odfA:
undetectable		 5jlcA-1odfA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 202
PHE A  35
GLY A 164
PHE A 259
LEU A 158
 None
 1.10A 6dwnC-1odfA:
0.0		 6dwnC-1odfA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 202
PHE A  35
GLY A 164
PHE A 259
LEU A 158
 None
 1.07A 6dwnD-1odfA:
0.0		 6dwnD-1odfA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  72
SER A  45
SER A  48
 None
SO4  A 501 (-3.1A)
None
 0.81A 6mxtA-1odfA:
undetectable		 6mxtA-1odfA:
21.41