SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1odg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		4 / 6 CYH A 117
ASP A 148
HIS A  71
CYH A  73
 ZN  A 200 (-2.5A)
None
ZN  A 200 (-2.9A)
ZN  A 200 (-1.9A)
 1.31A 1ekjG-1odgA:
undetectable
1ekjH-1odgA:
undetectable		 1ekjG-1odgA:
20.09
1ekjH-1odgA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 10 LEU A 134
ALA A 129
LEU A 125
LEU A 119
ARG A  27
 None
 1.28A 1pcgA-1odgA:
undetectable		 1pcgA-1odgA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 10 LEU A 134
ALA A 129
LEU A 125
LEU A 119
ARG A  27
 None
 1.31A 1pcgB-1odgA:
undetectable		 1pcgB-1odgA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKT_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 10 LEU A 134
ALA A 129
LEU A 125
LEU A 119
ARG A  27
 None
 1.39A 1qktA-1odgA:
undetectable		 1qktA-1odgA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		3 / 3 CYH A  73
HIS A  72
PHE A  76
 ZN  A 200 (-1.9A)
None
None
 0.86A 3cr4X-1odgA:
undetectable		 3cr4X-1odgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 9 GLY A  48
HIS A  64
ASP A  97
ILE A 101
VAL A  60
 None
 1.40A 3fi0C-1odgA:
undetectable		 3fi0C-1odgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 9 GLY A  48
HIS A  64
ASP A  97
ILE A 101
VAL A  60
 None
 1.41A 3fi0D-1odgA:
undetectable		 3fi0D-1odgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 8 GLY A  48
HIS A  64
ASP A  97
ILE A 101
VAL A  60
 None
 1.36A 3fi0I-1odgA:
undetectable		 3fi0I-1odgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 9 GLY A  48
HIS A  64
ASP A  97
ILE A 101
VAL A  60
 None
 1.41A 3fi0J-1odgA:
0.0		 3fi0J-1odgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 9 GLY A  48
HIS A  64
ASP A  97
ILE A 101
VAL A  60
 None
 1.38A 3fi0K-1odgA:
undetectable		 3fi0K-1odgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 9 GLY A  48
HIS A  64
ASP A  97
ILE A 101
VAL A  60
 None
 1.39A 3fi0N-1odgA:
undetectable		 3fi0N-1odgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 9 GLY A  48
HIS A  64
ASP A  97
ILE A 101
VAL A  60
 None
 1.37A 3fi0O-1odgA:
undetectable		 3fi0O-1odgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 10 LEU A 134
ALA A 129
LEU A 125
LEU A 119
ARG A  27
 None
 1.36A 5dxeB-1odgA:
undetectable		 5dxeB-1odgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		5 / 10 LEU A 134
ALA A 129
LEU A 125
LEU A 119
ARG A  27
 None
 1.34A 5hyrA-1odgA:
0.0		 5hyrA-1odgA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1odg DNA MISMATCH
ENDONUCLEASE
(Escherichia
coli) 		4 / 7 GLY A  48
VAL A 111
ILE A  61
VAL A  60
 None
 0.78A 5ik1A-1odgA:
undetectable		 5ik1A-1odgA:
15.92