SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1odi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 0.98A 1gtnB-1odiA:
undetectable
1gtnC-1odiA:
0.0		 1gtnB-1odiA:
14.71
1gtnC-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.01A 1gtnH-1odiA:
undetectable
1gtnI-1odiA:
undetectable		 1gtnH-1odiA:
14.71
1gtnI-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 8 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 0.96A 1gtnI-1odiA:
undetectable
1gtnJ-1odiA:
undetectable		 1gtnI-1odiA:
14.71
1gtnJ-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 11 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.07A 1gtnM-1odiA:
undetectable
1gtnN-1odiA:
undetectable		 1gtnM-1odiA:
14.71
1gtnN-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.07A 1gtnU-1odiA:
undetectable
1gtnV-1odiA:
undetectable		 1gtnU-1odiA:
14.71
1gtnV-1odiA:
14.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 ARG A  87
THR A  90
GLU A 179
MET A 180
GLU A 181
 SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.32A 1jdvA-1odiA:
34.8
1jdvD-1odiA:
17.6		 1jdvA-1odiA:
40.42
1jdvD-1odiA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 ARG A  87
THR A  90
GLU A 179
MET A 180
GLU A 181
 SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.34A 1jdvB-1odiA:
34.7
1jdvC-1odiA:
34.7		 1jdvB-1odiA:
40.42
1jdvC-1odiA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 ARG A  87
THR A  90
GLU A 179
MET A 180
GLU A 181
 SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.33A 1jdvA-1odiA:
34.8
1jdvD-1odiA:
17.6		 1jdvA-1odiA:
40.42
1jdvD-1odiA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 12 ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.42A 1jdvE-1odiA:
34.7
1jdvF-1odiA:
34.7		 1jdvE-1odiA:
40.42
1jdvF-1odiA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 ARG A  87
THR A  90
MET A  65
GLU A 181
SER A 203
 SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-4.1A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 1.41A 1jdvE-1odiA:
34.7
1jdvF-1odiA:
34.7		 1jdvE-1odiA:
40.42
1jdvF-1odiA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 9 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.48A 1pk7A-1odiA:
34.7		 1pk7A-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 8 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
ADN  A1237 (-4.4A)
 0.68A 1pk7B-1odiA:
35.4		 1pk7B-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 10 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.34A 1pk7C-1odiA:
36.2		 1pk7C-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 10 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.37A 1pk9A-1odiA:
34.8		 1pk9A-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 9 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.42A 1pk9B-1odiA:
35.1		 1pk9B-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		8 / 11 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
ADN  A1237 (-4.4A)
 0.40A 1pk9C-1odiA:
35.1		 1pk9C-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		8 / 10 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
ADN  A1237 (-4.4A)
 0.50A 1pw7A-1odiA:
34.8		 1pw7A-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 9 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 (-4.4A)
 0.53A 1pw7B-1odiA:
35.6		 1pw7B-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 9 MET A  65
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 ADN  A1237 (-4.1A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
ADN  A1237 (-4.4A)
 0.45A 1pw7C-1odiA:
36.0		 1pw7C-1odiA:
35.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.04A 1utdO-1odiA:
0.0
1utdP-1odiA:
undetectable		 1utdO-1odiA:
14.71
1utdP-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.05A 1utdT-1odiA:
0.0
1utdU-1odiA:
0.0		 1utdT-1odiA:
14.71
1utdU-1odiA:
14.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 (-4.4A)
 0.48A 1vhwA-1odiA:
36.1
1vhwD-1odiA:
36.1		 1vhwA-1odiA:
33.88
1vhwD-1odiA:
33.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 9 MET A  65
ARG A  87
GLY A  92
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.41A 1vhwB-1odiA:
36.2
1vhwF-1odiA:
35.7		 1vhwB-1odiA:
33.88
1vhwF-1odiA:
33.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 (-4.4A)
 0.49A 1vhwC-1odiA:
36.1
1vhwE-1odiA:
36.0		 1vhwC-1odiA:
33.88
1vhwE-1odiA:
33.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 (-4.4A)
 0.49A 1vhwA-1odiA:
36.1
1vhwD-1odiA:
36.0		 1vhwA-1odiA:
33.88
1vhwD-1odiA:
33.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 (-4.4A)
 0.47A 1vhwC-1odiA:
36.1
1vhwE-1odiA:
36.0		 1vhwC-1odiA:
33.88
1vhwE-1odiA:
33.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 10 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.43A 1vhwB-1odiA:
36.2
1vhwF-1odiA:
35.7		 1vhwB-1odiA:
33.88
1vhwF-1odiA:
33.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		8 / 10 MET A  65
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.50A 1z35A-1odiA:
36.0		 1z35A-1odiA:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		8 / 9 MET A  65
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.43A 1z37A-1odiA:
36.1		 1z37A-1odiA:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.22A 2ac7A-1odiA:
35.4
2ac7B-1odiA:
35.4		 2ac7A-1odiA:
40.17
2ac7B-1odiA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.23A 2ac7A-1odiA:
35.4
2ac7B-1odiA:
35.4		 2ac7A-1odiA:
40.17
2ac7B-1odiA:
40.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		4 / 5 LEU A 200
GLY A 174
ALA A 106
ILE A 104
 None
 0.86A 2aohB-1odiA:
undetectable		 2aohB-1odiA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		4 / 6 LEU A  34
LEU A 229
PRO A  20
VAL A  88
 None
 1.19A 2dqyC-1odiA:
undetectable		 2dqyC-1odiA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 10 ALA A 177
ALA A 171
ALA A  94
VAL A 202
GLY A 151
ASP A  97
 None
 1.30A 2f16K-1odiA:
undetectable
2f16L-1odiA:
undetectable		 2f16K-1odiA:
26.12
2f16L-1odiA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 10 ALA A 177
ALA A 171
ALA A  94
VAL A 202
GLY A 151
ASP A  97
 None
 1.32A 2f16Y-1odiA:
undetectable
2f16Z-1odiA:
undetectable		 2f16Y-1odiA:
26.12
2f16Z-1odiA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 THR A  90
GLY A  92
PHE A 159
GLU A 179
MET A 180
 SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.3A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
 0.41A 3kvrA-1odiA:
25.4		 3kvrA-1odiA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 THR A  90
GLY A  92
PHE A 159
GLU A 179
MET A 180
 SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.3A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
 0.43A 3kvrB-1odiA:
25.3		 3kvrB-1odiA:
25.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 9 MET A  65
ARG A  87
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.48A 3u40A-1odiA:
34.0
3u40F-1odiA:
33.1		 3u40A-1odiA:
36.14
3u40F-1odiA:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 MET A  65
ARG A  87
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.47A 3u40B-1odiA:
33.5
3u40C-1odiA:
33.8		 3u40B-1odiA:
36.14
3u40C-1odiA:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 12 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.43A 3u40B-1odiA:
33.5
3u40C-1odiA:
33.8		 3u40B-1odiA:
36.14
3u40C-1odiA:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 11 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.40A 3u40D-1odiA:
34.4
3u40E-1odiA:
33.2		 3u40D-1odiA:
36.14
3u40E-1odiA:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 12 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.49A 3u40D-1odiA:
34.4
3u40E-1odiA:
33.2		 3u40D-1odiA:
36.14
3u40E-1odiA:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 MET A  65
ARG A  87
GLU A 179
MET A 180
GLU A 181
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
 0.41A 3u40A-1odiA:
34.0
3u40F-1odiA:
33.1		 3u40A-1odiA:
36.14
3u40F-1odiA:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		9 / 11 MET A  65
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
ADN  A1237 (-4.4A)
 0.28A 3uawA-1odiA:
37.3		 3uawA-1odiA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		9 / 10 MET A  65
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
ASN A 204
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
SO4  A1236 ( 3.0A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 (-3.2A)
ADN  A1237 (-4.4A)
 0.28A 3uayA-1odiA:
36.6		 3uayA-1odiA:
40.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.12A 4coxC-1odiA:
0.3		 4coxC-1odiA:
16.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.36A 4d9hA-1odiA:
35.3		 4d9hA-1odiA:
36.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 9 MET A  65
GLY A  92
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
ADN  A1237 (-3.4A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.71A 4da6A-1odiA:
35.2		 4da6A-1odiA:
36.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 10 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.45A 4da7A-1odiA:
35.3		 4da7A-1odiA:
36.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.50A 4danA-1odiA:
34.9		 4danA-1odiA:
36.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 12 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
 0.56A 4danA-1odiA:
34.9
4danB-1odiA:
35.2		 4danA-1odiA:
36.22
4danB-1odiA:
36.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		3 / 3 TYR A 146
PHE A  33
ARG A 222
 None
 0.97A 4g19D-1odiA:
0.1		 4g19D-1odiA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 VAL A  17
VAL A  73
LEU A  77
GLY A  21
LEU A  19
 None
None
None
SO4  A1236 (-3.1A)
None
 1.11A 4ph9A-1odiA:
0.8		 4ph9A-1odiA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 VAL A  17
VAL A  73
LEU A  77
GLY A  21
LEU A  19
 None
None
None
SO4  A1236 (-3.1A)
None
 1.10A 4ph9B-1odiA:
undetectable		 4ph9B-1odiA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.10A 4rrwA-1odiA:
undetectable		 4rrwA-1odiA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.09A 4rrwB-1odiA:
0.7		 4rrwB-1odiA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.10A 4rrzA-1odiA:
undetectable		 4rrzA-1odiA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.09A 4rrzB-1odiA:
0.7		 4rrzB-1odiA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 9 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.03A 4rs0A-1odiA:
1.2		 4rs0A-1odiA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 GLY A  66
GLU A 181
GLY A  64
GLY A  21
SER A  69
 None
ADN  A1237 (-3.0A)
None
SO4  A1236 (-3.1A)
None
 0.97A 4uckA-1odiA:
undetectable		 4uckA-1odiA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		3 / 3 VAL A  86
LEU A  18
VAL A  88
 None
 0.62A 4wq4A-1odiA:
undetectable		 4wq4A-1odiA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 THR A  90
GLY A  66
PRO A  68
SER A  69
ALA A  70
 SO4  A1236 ( 3.0A)
None
None
None
None
 1.06A 4ypmA-1odiA:
undetectable		 4ypmA-1odiA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.01A 5eeuF-1odiA:
undetectable
5eeuG-1odiA:
undetectable		 5eeuF-1odiA:
14.71
5eeuG-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5eeuI-1odiA:
0.0
5eeuJ-1odiA:
undetectable		 5eeuI-1odiA:
14.71
5eeuJ-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.04A 5eeuO-1odiA:
0.0
5eeuP-1odiA:
0.0		 5eeuO-1odiA:
14.71
5eeuP-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.05A 5eeuQ-1odiA:
undetectable
5eeuR-1odiA:
0.0		 5eeuQ-1odiA:
14.71
5eeuR-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.01A 5eevF-1odiA:
undetectable
5eevG-1odiA:
undetectable		 5eevF-1odiA:
14.71
5eevG-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5eevI-1odiA:
0.0
5eevJ-1odiA:
0.0		 5eevI-1odiA:
14.71
5eevJ-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.04A 5eevO-1odiA:
0.0
5eevP-1odiA:
0.0		 5eevO-1odiA:
14.71
5eevP-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.05A 5eevQ-1odiA:
undetectable
5eevR-1odiA:
0.0		 5eevQ-1odiA:
14.71
5eevR-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.01A 5eewF-1odiA:
undetectable
5eewG-1odiA:
undetectable		 5eewF-1odiA:
14.71
5eewG-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5eewI-1odiA:
0.0
5eewJ-1odiA:
0.0		 5eewI-1odiA:
14.71
5eewJ-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.04A 5eewO-1odiA:
0.0
5eewP-1odiA:
0.0		 5eewO-1odiA:
14.71
5eewP-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.05A 5eewQ-1odiA:
0.0
5eewR-1odiA:
0.0		 5eewQ-1odiA:
14.71
5eewR-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.01A 5eexF-1odiA:
undetectable
5eexG-1odiA:
undetectable		 5eexF-1odiA:
14.71
5eexG-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.04A 5eexO-1odiA:
0.0
5eexP-1odiA:
0.0		 5eexO-1odiA:
14.71
5eexP-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5eeyF-1odiA:
undetectable
5eeyG-1odiA:
undetectable		 5eeyF-1odiA:
14.71
5eeyG-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.04A 5eeyO-1odiA:
0.0
5eeyP-1odiA:
0.0		 5eeyO-1odiA:
14.71
5eeyP-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5eezF-1odiA:
undetectable
5eezG-1odiA:
undetectable		 5eezF-1odiA:
14.71
5eezG-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.04A 5eezO-1odiA:
0.0
5eezP-1odiA:
0.0		 5eezO-1odiA:
14.71
5eezP-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5ef0F-1odiA:
undetectable
5ef0G-1odiA:
undetectable		 5ef0F-1odiA:
14.71
5ef0G-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.04A 5ef0O-1odiA:
0.0
5ef0P-1odiA:
0.0		 5ef0O-1odiA:
14.71
5ef0P-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5ef1F-1odiA:
undetectable
5ef1G-1odiA:
undetectable		 5ef1F-1odiA:
14.71
5ef1G-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.03A 5ef1O-1odiA:
0.0
5ef1P-1odiA:
0.0		 5ef1O-1odiA:
14.71
5ef1P-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5ef2F-1odiA:
undetectable
5ef2G-1odiA:
undetectable		 5ef2F-1odiA:
14.71
5ef2G-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.03A 5ef2O-1odiA:
0.0
5ef2P-1odiA:
0.0		 5ef2O-1odiA:
14.71
5ef2P-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 SER A  95
ALA A  94
GLY A 151
ALA A 177
ILE A 104
 None
 1.00A 5ef3F-1odiA:
undetectable
5ef3G-1odiA:
undetectable		 5ef3F-1odiA:
14.71
5ef3G-1odiA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 10 GLY A 151
ALA A 177
ILE A 104
SER A  95
ALA A  94
 None
 1.03A 5ef3O-1odiA:
undetectable
5ef3P-1odiA:
0.0		 5ef3O-1odiA:
14.71
5ef3P-1odiA:
14.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 9 MET A  65
ARG A  87
GLY A  92
MET A 180
GLU A 181
ILE A 206
 ADN  A1237 (-4.1A)
SO4  A1236 ( 2.8A)
ADN  A1237 (-3.4A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 (-4.4A)
 0.46A 5i3cA-1odiA:
36.0		 5i3cA-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		6 / 10 MET A  65
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A 206
 ADN  A1237 (-4.1A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 (-4.4A)
 0.35A 5i3cB-1odiA:
36.5		 5i3cB-1odiA:
35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		7 / 11 MET A  65
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 ADN  A1237 (-4.1A)
ADN  A1237 (-3.4A)
ADN  A1237 (-4.9A)
ADN  A1237 (-3.7A)
ADN  A1237 (-3.0A)
ADN  A1237 ( 3.7A)
ADN  A1237 (-4.4A)
 0.52A 5i3cC-1odiA:
36.1		 5i3cC-1odiA:
35.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.14A 5ikrA-1odiA:
undetectable		 5ikrA-1odiA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.11A 5jvzB-1odiA:
0.0		 5jvzB-1odiA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		5 / 12 VAL A 153
SER A 155
GLY A  92
ALA A  91
LEU A 200
 None
None
ADN  A1237 (-3.4A)
None
None
 1.09A 5kirB-1odiA:
undetectable		 5kirB-1odiA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		4 / 7 ILE A 199
VAL A  58
LEU A  18
LEU A 233
 None
 0.70A 6g9bA-1odiA:
0.0
6g9bB-1odiA:
0.0		 6g9bA-1odiA:
16.03
6g9bB-1odiA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1odi PURINE NUCLEOSIDE
PHOSPHORYLASE
(Thermus
thermophilus) 		3 / 3 VAL A   6
ALA A   8
GLN A  61
 None
 0.68A 6gb9A-1odiA:
4.2		 6gb9A-1odiA:
19.78