SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1odo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 ALA A 184
VAL A 174
TRP A  81
 None
None
PIM  A1408 (-4.6A)
 0.78A 1av2A-1odoA:
undetectable
1av2B-1odoA:
undetectable		 1av2A-1odoA:
14.86
1av2B-1odoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 TRP A  81
ALA A 184
VAL A 174
 PIM  A1408 (-4.6A)
None
None
 0.61A 1av2C-1odoA:
undetectable
1av2D-1odoA:
undetectable		 1av2C-1odoA:
14.86
1av2D-1odoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 11 LEU A  49
ILE A 301
ILE A 309
VAL A  58
GLN A  51
 None
 1.00A 1gx9A-1odoA:
undetectable		 1gx9A-1odoA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 12 LEU A 198
LEU A 195
VAL A 194
SER A 241
VAL A 159
 None
None
None
PIM  A1408 (-4.3A)
None
 1.37A 1ie9A-1odoA:
1.2		 1ie9A-1odoA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 8 VAL A  82
VAL A  33
VAL A  35
ILE A 394
LEU A 294
 None
 1.49A 1igxA-1odoA:
undetectable		 1igxA-1odoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 7 ARG A 141
ALA A 145
ILE A 150
PRO A 149
 None
 1.12A 1oniA-1odoA:
undetectable
1oniB-1odoA:
undetectable		 1oniA-1odoA:
19.55
1oniB-1odoA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 ARG A 141
ALA A 145
ILE A 150
PRO A 149
 None
 1.06A 1oniB-1odoA:
undetectable
1oniC-1odoA:
undetectable		 1oniB-1odoA:
19.55
1oniC-1odoA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 7 ILE A 150
PRO A 149
ARG A 141
ALA A 145
 None
 1.07A 1oniD-1odoA:
undetectable
1oniE-1odoA:
undetectable		 1oniD-1odoA:
19.55
1oniE-1odoA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 ARG A 141
ALA A 145
ILE A 150
PRO A 149
 None
 1.03A 1oniH-1odoA:
undetectable
1oniI-1odoA:
undetectable		 1oniH-1odoA:
19.55
1oniI-1odoA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 7 ILE A 150
PRO A 149
ARG A 141
ALA A 145
 None
 1.10A 1oniG-1odoA:
undetectable
1oniI-1odoA:
undetectable		 1oniG-1odoA:
19.55
1oniI-1odoA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 12 LEU A  24
LEU A   8
ALA A   7
LEU A 393
HIS A 291
 None
 1.11A 1s9pD-1odoA:
2.4		 1s9pD-1odoA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.70A 1w2zA-1odoA:
undetectable		 1w2zA-1odoA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.68A 1w2zB-1odoA:
undetectable		 1w2zB-1odoA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.71A 1w2zC-1odoA:
undetectable		 1w2zC-1odoA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.70A 1w2zD-1odoA:
undetectable		 1w2zD-1odoA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 ALA A 184
VAL A 174
TRP A  81
 None
None
PIM  A1408 (-4.6A)
 0.78A 1w5uA-1odoA:
undetectable
1w5uB-1odoA:
undetectable		 1w5uA-1odoA:
14.86
1w5uB-1odoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 TRP A  81
ALA A 184
VAL A 174
 PIM  A1408 (-4.6A)
None
None
 0.74A 1w5uA-1odoA:
undetectable
1w5uB-1odoA:
undetectable		 1w5uA-1odoA:
14.86
1w5uB-1odoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 8 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.93A 2eijN-1odoA:
0.0
2eijW-1odoA:
0.0		 2eijN-1odoA:
23.13
2eijW-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 ALA A 184
VAL A 174
TRP A  81
 None
None
PIM  A1408 (-4.6A)
 0.65A 2izqA-1odoA:
undetectable
2izqB-1odoA:
undetectable		 2izqA-1odoA:
14.86
2izqB-1odoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 TRP A  81
ALA A 184
VAL A 174
 PIM  A1408 (-4.6A)
None
None
 0.83A 2izqC-1odoA:
undetectable
2izqD-1odoA:
undetectable		 2izqC-1odoA:
14.86
2izqD-1odoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.71A 2oqeA-1odoA:
undetectable		 2oqeA-1odoA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.71A 2oqeB-1odoA:
undetectable		 2oqeB-1odoA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.72A 2oqeC-1odoA:
undetectable		 2oqeC-1odoA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.72A 2oqeD-1odoA:
undetectable		 2oqeD-1odoA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 HIS A  17
HIS A  21
HIS A  18
 None
 0.72A 2oqeF-1odoA:
undetectable		 2oqeF-1odoA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 LEU A 294
PRO A 293
LEU A 316
 None
 0.50A 2po5B-1odoA:
undetectable		 2po5B-1odoA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 LEU A 294
PRO A 293
LEU A 316
 None
 0.53A 2po7B-1odoA:
undetectable		 2po7B-1odoA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 8 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.93A 3abkA-1odoA:
0.2
3abkJ-1odoA:
undetectable		 3abkA-1odoA:
23.13
3abkJ-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 8 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.87A 3ablN-1odoA:
0.0
3ablW-1odoA:
0.0		 3ablN-1odoA:
23.13
3ablW-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 8 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.90A 3asoN-1odoA:
undetectable
3asoW-1odoA:
undetectable		 3asoN-1odoA:
23.13
3asoW-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 12 ALA A 367
LEU A 144
GLN A 253
LEU A 259
PHE A 372
 None
 0.99A 3datA-1odoA:
undetectable		 3datA-1odoA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 ALA A 242
THR A 246
CYH A 354
 HEM  A1407 ( 3.4A)
HEM  A1407 ( 3.1A)
HEM  A1407 (-2.3A)
 0.50A 3e4eA-1odoA:
31.2		 3e4eA-1odoA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 ALA A 242
THR A 246
CYH A 354
 HEM  A1407 ( 3.4A)
HEM  A1407 ( 3.1A)
HEM  A1407 (-2.3A)
 0.44A 3e4eB-1odoA:
31.1		 3e4eB-1odoA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 VAL A 279
VAL A 268
TRP A 275
PHE A 372
 None
 1.44A 3jx4A-1odoA:
1.6
3jx4B-1odoA:
1.7		 3jx4A-1odoA:
20.70
3jx4B-1odoA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 TRP A  81
ALA A 184
VAL A 174
 PIM  A1408 (-4.6A)
None
None
 0.62A 3l8lA-1odoA:
undetectable
3l8lB-1odoA:
undetectable		 3l8lA-1odoA:
14.86
3l8lB-1odoA:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 TRP A  81
ALA A 184
VAL A 174
 PIM  A1408 (-4.6A)
None
None
 0.79A 3l8lC-1odoA:
undetectable
3l8lD-1odoA:
undetectable		 3l8lC-1odoA:
14.86
3l8lD-1odoA:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 LEU A  98
HIS A  95
MET A  87
THR A 235
 None
HEM  A1407 (-3.8A)
HEM  A1407 (-3.6A)
None
 1.42A 3thrB-1odoA:
undetectable		 3thrB-1odoA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 GLU A 281
ASP A 336
ASP A 333
 None
 0.78A 4gc9A-1odoA:
undetectable		 4gc9A-1odoA:
24.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 11 PHE A  88
ALA A 242
THR A 246
VAL A 289
LEU A 292
 PIM  A1408 (-3.6A)
HEM  A1407 ( 3.4A)
HEM  A1407 ( 3.1A)
None
HEM  A1407 ( 4.2A)
 0.83A 4j6cA-1odoA:
54.0		 4j6cA-1odoA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 12 PHE A  88
ALA A 242
THR A 246
VAL A 289
LEU A 292
 PIM  A1408 (-3.6A)
HEM  A1407 ( 3.4A)
HEM  A1407 ( 3.1A)
None
HEM  A1407 ( 4.2A)
 0.85A 4j6dA-1odoA:
54.2		 4j6dA-1odoA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 12 PHE A  88
ALA A 242
THR A 246
VAL A 289
LEU A 292
 PIM  A1408 (-3.6A)
HEM  A1407 ( 3.4A)
HEM  A1407 ( 3.1A)
None
HEM  A1407 ( 4.2A)
 0.87A 4j6dB-1odoA:
54.2		 4j6dB-1odoA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 12 PHE A  88
ALA A 242
THR A 246
VAL A 289
LEU A 292
 PIM  A1408 (-3.6A)
HEM  A1407 ( 3.4A)
HEM  A1407 ( 3.1A)
None
HEM  A1407 ( 4.2A)
 0.81A 4jbtA-1odoA:
54.1		 4jbtA-1odoA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 11 PHE A  88
ALA A 242
THR A 246
VAL A 289
LEU A 292
 PIM  A1408 (-3.6A)
HEM  A1407 ( 3.4A)
HEM  A1407 ( 3.1A)
None
HEM  A1407 ( 4.2A)
 0.82A 4jbtB-1odoA:
54.2		 4jbtB-1odoA:
40.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ4_A_IMNA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 10 VAL A 171
TYR A 244
VAL A 174
LEU A 198
LEU A 195
 None
 1.37A 4jq4A-1odoA:
undetectable		 4jq4A-1odoA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 VAL A 278
ALA A 254
PHE A 335
 None
 0.93A 4olbA-1odoA:
undetectable		 4olbA-1odoA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 LEU A 237
ILE A 240
LEU A 191
TYR A 192
 None
 0.93A 4w5nA-1odoA:
undetectable		 4w5nA-1odoA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 LEU A 366
VAL A 111
ASP A 112
 None
 0.60A 4y8wC-1odoA:
34.0		 4y8wC-1odoA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 VAL A 279
VAL A 268
TRP A 275
PHE A 372
 None
 1.46A 5adeA-1odoA:
0.0
5adeB-1odoA:
0.0		 5adeA-1odoA:
20.70
5adeB-1odoA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 7 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.87A 5b1bN-1odoA:
0.0
5b1bW-1odoA:
undetectable		 5b1bN-1odoA:
23.13
5b1bW-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 7 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.88A 5b3sN-1odoA:
0.2
5b3sW-1odoA:
0.0		 5b3sN-1odoA:
23.13
5b3sW-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 12 LEU A   8
GLY A  37
PRO A  77
LEU A  78
LEU A  10
 None
 1.27A 5emlA-1odoA:
undetectable		 5emlA-1odoA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 ILE A 215
MET A 239
ASP A 209
 None
HEM  A1407 (-3.6A)
None
 0.85A 5h2uA-1odoA:
undetectable		 5h2uA-1odoA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_B_GLYB404_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 4 GLN A 181
ALA A 184
GLN A 185
THR A 188
 None
 1.10A 5hhjB-1odoA:
undetectable		 5hhjB-1odoA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_A_URFA301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 4 ARG A 339
ASP A 336
HIS A 285
ARG A 284
 None
 1.21A 5iaoA-1odoA:
0.0		 5iaoA-1odoA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 ARG A 339
HIS A 285
ARG A 284
 None
 0.84A 5iaoC-1odoA:
undetectable		 5iaoC-1odoA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 ARG A 339
HIS A 285
ARG A 284
 None
 0.82A 5iaoF-1odoA:
undetectable		 5iaoF-1odoA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 VAL A 250
LEU A 238
MET A 239
 None
HEM  A1407 (-4.6A)
HEM  A1407 (-3.6A)
 0.85A 5ikrA-1odoA:
0.0		 5ikrA-1odoA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 7 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.93A 5iy5N-1odoA:
0.0
5iy5W-1odoA:
0.0		 5iy5N-1odoA:
23.13
5iy5W-1odoA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 GLU A  20
HIS A  21
ARG A  25
 None
 0.76A 5uunA-1odoA:
0.0		 5uunA-1odoA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		3 / 3 LEU A 405
VAL A 126
ASP A 127
 None
 0.66A 5x23A-1odoA:
29.5		 5x23A-1odoA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 8 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.88A 5xdxN-1odoA:
0.1
5xdxW-1odoA:
0.0		 5xdxN-1odoA:
23.13
5xdxW-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 5 TRP A  81
LEU A  80
VAL A  84
LEU A 237
 PIM  A1408 (-4.6A)
None
None
None
 0.88A 5xooB-1odoA:
0.0		 5xooB-1odoA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 8 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.90A 5zcoA-1odoA:
0.0
5zcoJ-1odoA:
0.0		 5zcoA-1odoA:
23.13
5zcoJ-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 8 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.93A 5zcpN-1odoA:
undetectable
5zcpW-1odoA:
undetectable		 5zcpN-1odoA:
23.13
5zcpW-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 8 PHE A 106
MET A 210
THR A 211
LEU A 214
 HEM  A1407 (-4.5A)
None
None
None
 0.89A 5zcqN-1odoA:
0.0
5zcqW-1odoA:
0.0		 5zcqN-1odoA:
23.13
5zcqW-1odoA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 10 PHE A 167
LEU A 170
SER A 241
GLY A 243
ILE A 240
 None
None
PIM  A1408 (-4.3A)
HEM  A1407 ( 4.4A)
None
 1.25A 6ebpB-1odoA:
undetectable		 6ebpB-1odoA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 10 VAL A  33
ALA A  40
LEU A  10
LEU A 393
LEU A  24
 None
 0.82A 6f5uA-1odoA:
undetectable
6f5uB-1odoA:
0.0		 6f5uA-1odoA:
10.29
6f5uB-1odoA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 GLN A  39
GLU A 313
TRP A  66
ALA A  40
 None
 1.39A 6f6jC-1odoA:
0.0
6f6jD-1odoA:
0.0		 6f6jC-1odoA:
24.38
6f6jD-1odoA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 GLU A 313
TRP A  66
ALA A  40
GLN A  39
 None
 1.32A 6f6jC-1odoA:
0.0
6f6jD-1odoA:
0.0		 6f6jC-1odoA:
24.38
6f6jD-1odoA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 10 VAL A  33
ALA A  40
LEU A  10
LEU A 393
LEU A  24
 None
 0.94A 6f6nA-1odoA:
undetectable
6f6nB-1odoA:
0.0		 6f6nA-1odoA:
10.29
6f6nB-1odoA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		5 / 10 VAL A 403
LEU A 378
LEU A 371
LEU A 258
LEU A 259
 None
 1.01A 6f6nA-1odoA:
undetectable
6f6nB-1odoA:
0.0		 6f6nA-1odoA:
10.29
6f6nB-1odoA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1odo PUTATIVE CYTOCHROME
P450 154A1
(Streptomyces
coelicolor) 		4 / 6 VAL A 126
LEU A 144
LEU A 140
LEU A 368
 None
 0.70A 6f6sA-1odoA:
0.0
6f6sB-1odoA:
0.0		 6f6sA-1odoA:
10.29
6f6sB-1odoA:
14.41