SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1odt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		3 / 3 MET C 242
LEU C 245
SER C 246
 None
 0.60A 1ee2A-1odtC:
2.5		 1ee2A-1odtC:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 7 PHE C 304
GLU C 289
LEU C 290
VAL C 277
 None
 0.93A 1hk2A-1odtC:
undetectable		 1hk2A-1odtC:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 11 SER C 264
PHE C 278
ALA C 280
ALA C 191
ALA C 190
 None
 1.06A 1jinA-1odtC:
undetectable		 1jinA-1odtC:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 6 ALA C 200
TYR C  88
ILE C 175
PRO C 197
 None
 1.17A 1oniB-1odtC:
undetectable
1oniC-1odtC:
undetectable		 1oniB-1odtC:
17.72
1oniC-1odtC:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 7 TYR C  88
ILE C 175
PRO C 197
ALA C 200
 None
 1.14A 1oniD-1odtC:
undetectable
1oniE-1odtC:
undetectable		 1oniD-1odtC:
17.72
1oniE-1odtC:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 7 VAL C 177
GLY C 176
ASP C 195
VAL C 259
 None
 0.81A 1p2yA-1odtC:
0.0		 1p2yA-1odtC:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 11 GLY C  90
ALA C 181
LEU C 207
VAL C 271
HIS C 298
 ACT  C1318 (-3.6A)
ACT  C1318 (-3.0A)
None
None
ACT  C1318 (-4.0A)
 0.52A 1ukbA-1odtC:
17.2		 1ukbA-1odtC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 12 LEU C 245
GLY C 141
ASP C 146
GLY C 152
VAL C 153
 None
 1.02A 2f8gA-1odtC:
undetectable		 2f8gA-1odtC:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 7 PRO C 197
ALA C 190
ALA C 160
PHE C 113
 None
 0.95A 2vcvL-1odtC:
0.0		 2vcvL-1odtC:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 12 LEU C 245
GLY C 141
ASP C 146
GLY C 152
VAL C 153
 None
 1.00A 3cyxA-1odtC:
undetectable		 3cyxA-1odtC:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 4 PRO C 274
THR C 272
GLY C 179
THR C 178
 None
 1.18A 3ib1A-1odtC:
undetectable		 3ib1A-1odtC:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 12 GLY C 179
VAL C 177
VAL C  86
ALA C 181
ILE C 188
 None
None
None
ACT  C1318 (-3.0A)
None
 1.01A 3ku1H-1odtC:
undetectable		 3ku1H-1odtC:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 10 LEU C 245
GLY C 141
ASP C 146
GLY C 152
VAL C 153
 None
 1.03A 3oxwA-1odtC:
undetectable		 3oxwA-1odtC:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 10 ALA C 106
VAL C  56
PRO C  50
ALA C  51
VAL C  54
 None
 0.90A 3t3cB-1odtC:
undetectable		 3t3cB-1odtC:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 7 LEU C 207
ALA C 189
VAL C 261
ILE C 250
 None
 0.94A 3wsjB-1odtC:
undetectable		 3wsjB-1odtC:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 7 ASP C 249
SER C 208
TYR C  14
HIS C 283
 None
 1.30A 4arcA-1odtC:
0.1		 4arcA-1odtC:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		3 / 3 LYS C 243
PRO C  21
LYS C 145
 None
 1.46A 4dv7L-1odtC:
0.0		 4dv7L-1odtC:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 5 THR C 178
THR C 187
THR C 272
HIS C 298
 None
None
None
ACT  C1318 (-4.0A)
 1.35A 4pgfB-1odtC:
4.4		 4pgfB-1odtC:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 11 LEU C 245
ASP C 144
GLN C 240
ALA C 241
ASP C  23
 None
 1.25A 4uuuA-1odtC:
undetectable
4uuuB-1odtC:
undetectable		 4uuuA-1odtC:
18.50
4uuuB-1odtC:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		3 / 3 TYR C 149
TYR C 206
GLN C 182
 None
ACT  C1318 (-3.6A)
None
 1.16A 5jsdB-1odtC:
0.4
5jsdC-1odtC:
0.0		 5jsdB-1odtC:
17.33
5jsdC-1odtC:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 6 MET C 115
ALA C 160
LEU C 161
ILE C 175
 None
 0.75A 5mvmB-1odtC:
undetectable
5mvmC-1odtC:
undetectable		 5mvmB-1odtC:
14.79
5mvmC-1odtC:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 12 LEU C  59
GLY C 114
LYS C  87
GLU C 162
LEU C 161
 None
 1.16A 5nwvA-1odtC:
undetectable		 5nwvA-1odtC:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		3 / 3 LEU C 193
ALA C 190
LEU C  32
 None
 0.48A 5uunB-1odtC:
undetectable		 5uunB-1odtC:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WQP_A_NCAA302_0
(PROBABLE
DEHYDROGENASE)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		4 / 8 SER C  94
GLN C 121
TRP C  72
MET C 102
 None
 1.18A 5wqpA-1odtC:
3.1		 5wqpA-1odtC:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1odt CEPHALOSPORIN C
DEACETYLASE
(Bacillus
subtilis) 		5 / 12 VAL C 277
THR C 272
LEU C 290
VAL C 292
GLY C 266
 None
 1.05A 6a94B-1odtC:
0.0		 6a94B-1odtC:
21.72