SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oe5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 7 PHE A 156
VAL A 224
GLY A 223
VAL A  90
 None
 0.81A 1t88A-1oe5A:
undetectable		 1t88A-1oe5A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 8 PHE A 156
VAL A 224
GLY A 223
VAL A  90
 None
 0.86A 2a1oA-1oe5A:
0.0		 2a1oA-1oe5A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 11 LEU A 236
ILE A 241
GLY A 240
LEU A 209
CYH A 210
 None
 0.68A 2qmmA-1oe5A:
undetectable
2qmmB-1oe5A:
undetectable		 2qmmA-1oe5A:
22.31
2qmmB-1oe5A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 7 TRP A 153
GLY A  94
ILE A 222
PHE A 156
 None
URA  A1282 (-3.6A)
None
None
 1.04A 2qmzA-1oe5A:
undetectable
2qmzB-1oe5A:
undetectable		 2qmzA-1oe5A:
21.80
2qmzB-1oe5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		3 / 3 LYS A 219
ARG A 214
VAL A 213
 None
 0.96A 2r2vC-1oe5A:
0.0
2r2vD-1oe5A:
undetectable		 2r2vC-1oe5A:
8.79
2r2vD-1oe5A:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 7 LEU A 201
LEU A 193
PHE A  58
LEU A  53
 None
 0.92A 2vq5B-1oe5A:
undetectable		 2vq5B-1oe5A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 9 LEU A 236
ILE A 241
GLY A 240
LEU A 209
CYH A 210
 None
 0.73A 3ai9X-1oe5A:
undetectable		 3ai9X-1oe5A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 6 LEU A 236
GLY A 240
LEU A 209
CYH A 210
 None
 0.82A 3aiaA-1oe5A:
1.6		 3aiaA-1oe5A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 8 LEU A  53
SER A  54
LEU A 193
ILE A 204
 None
EPE  A1285 (-4.5A)
None
None
 0.93A 3ln1A-1oe5A:
undetectable		 3ln1A-1oe5A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 7 LEU A  53
SER A  54
LEU A 193
ILE A 204
 None
EPE  A1285 (-4.5A)
None
None
 0.91A 3ln1B-1oe5A:
undetectable		 3ln1B-1oe5A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		3 / 3 GLU A  77
LEU A  43
LEU A  51
 None
 0.77A 3ohtA-1oe5A:
undetectable		 3ohtA-1oe5A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 12 GLY A 110
GLY A 149
ASN A 113
VAL A 115
LEU A 119
 None
 1.13A 4fr0A-1oe5A:
undetectable		 4fr0A-1oe5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 12 VAL A  90
CYH A 170
PHE A 166
VAL A 275
LEU A 270
 None
 1.37A 4po0A-1oe5A:
undetectable		 4po0A-1oe5A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 8 GLY A  94
PHE A 109
SER A 148
ASN A 174
HIS A 250
 URA  A1282 (-3.6A)
URA  A1282 (-3.6A)
URA  A1282 ( 4.4A)
URA  A1282 (-3.0A)
URA  A1282 (-4.1A)
 0.39A 4wryA-1oe5A:
10.4		 4wryA-1oe5A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 8 GLY A  94
PHE A 109
SER A 148
ASN A 174
HIS A 250
 URA  A1282 (-3.6A)
URA  A1282 (-3.6A)
URA  A1282 ( 4.4A)
URA  A1282 (-3.0A)
URA  A1282 (-4.1A)
 0.44A 4wrzA-1oe5A:
10.1		 4wrzA-1oe5A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 7 GLY A  94
PHE A 109
ASN A 174
HIS A 250
 URA  A1282 (-3.6A)
URA  A1282 (-3.6A)
URA  A1282 (-3.0A)
URA  A1282 (-4.1A)
 0.42A 4ws0A-1oe5A:
9.8		 4ws0A-1oe5A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 8 GLY A  94
PHE A 109
SER A 148
ASN A 174
HIS A 250
 URA  A1282 (-3.6A)
URA  A1282 (-3.6A)
URA  A1282 ( 4.4A)
URA  A1282 (-3.0A)
URA  A1282 (-4.1A)
 0.45A 4ws1A-1oe5A:
9.7		 4ws1A-1oe5A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 6 HIS A 175
LEU A  93
CYH A 210
LEU A 236
 None
 0.98A 5hrqD-1oe5A:
undetectable
5hrqG-1oe5A:
undetectable
5hrqH-1oe5A:
undetectable		 5hrqD-1oe5A:
9.21
5hrqG-1oe5A:
9.46
5hrqH-1oe5A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		4 / 6 HIS A 175
LEU A  93
CYH A 210
LEU A 236
 None
 1.03A 5hrqB-1oe5A:
undetectable
5hrqI-1oe5A:
undetectable
5hrqJ-1oe5A:
undetectable		 5hrqB-1oe5A:
9.21
5hrqI-1oe5A:
9.46
5hrqJ-1oe5A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 12 ILE A 222
LEU A 270
PHE A  92
ASN A 174
GLY A 223
 None
None
None
URA  A1282 (-3.0A)
None
 1.26A 5il1A-1oe5A:
undetectable		 5il1A-1oe5A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 12 ILE A 222
LEU A 270
PHE A  92
ASN A 174
GLY A 223
 None
None
None
URA  A1282 (-3.0A)
None
 1.26A 5k7uA-1oe5A:
undetectable		 5k7uA-1oe5A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 12 ASN A 174
GLY A  94
LEU A 119
GLY A 149
SER A 148
 URA  A1282 (-3.0A)
URA  A1282 (-3.6A)
None
None
URA  A1282 ( 4.4A)
 1.16A 5vooB-1oe5A:
undetectable		 5vooB-1oe5A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 12 ASN A 174
GLY A  94
LEU A 119
GLY A 149
SER A 148
 URA  A1282 (-3.0A)
URA  A1282 (-3.6A)
None
None
URA  A1282 ( 4.4A)
 1.10A 5vooD-1oe5A:
undetectable		 5vooD-1oe5A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 12 VAL A 275
LEU A 220
GLY A 247
PHE A 227
ILE A 248
 None
 1.15A 5vooD-1oe5A:
undetectable		 5vooD-1oe5A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE
(Xenopus
laevis) 		5 / 12 ASN A 174
GLY A  94
LEU A 119
GLY A 149
SER A 148
 URA  A1282 (-3.0A)
URA  A1282 (-3.6A)
None
None
URA  A1282 ( 4.4A)
 1.04A 5vooF-1oe5A:
undetectable		 5vooF-1oe5A:
23.97