SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ofc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 1ofc ISWI PROTEIN
(Drosophila
melanogaster) 		3 / 3 ALA X 840
VAL X 835
TRP X 800
 None
 0.87A 1kqeA-1ofcX:
undetectable
1kqeE-1ofcX:
undetectable		 1kqeA-1ofcX:
3.24
1kqeE-1ofcX:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 1ofc ISWI PROTEIN
(Drosophila
melanogaster) 		3 / 3 ALA X 840
VAL X 835
TRP X 800
 None
 0.87A 1kqeB-1ofcX:
undetectable
1kqeD-1ofcX:
undetectable		 1kqeB-1ofcX:
3.24
1kqeD-1ofcX:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 1ofc ISWI PROTEIN
(Drosophila
melanogaster) 		3 / 3 TRP X 800
ALA X 840
VAL X 835
 None
 0.88A 1kqeB-1ofcX:
undetectable
1kqeD-1ofcX:
undetectable		 1kqeB-1ofcX:
3.24
1kqeD-1ofcX:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 1ofc ISWI PROTEIN
(Drosophila
melanogaster) 		3 / 3 TRP X 800
ALA X 840
VAL X 835
 None
 0.86A 1kqeA-1ofcX:
undetectable
1kqeE-1ofcX:
undetectable		 1kqeA-1ofcX:
3.24
1kqeE-1ofcX:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 1ofc ISWI PROTEIN
(Drosophila
melanogaster) 		3 / 3 ARG X 869
ASP X 826
GLN X 807
 None
 0.92A 4azsA-1ofcX:
undetectable		 4azsA-1ofcX:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 1ofc ISWI PROTEIN
(Drosophila
melanogaster) 		4 / 6 SER X 871
GLU X 964
GLY X 816
GLY X 862
 None
 0.87A 5cdpA-1ofcX:
1.5
5cdpB-1ofcX:
undetectable		 5cdpA-1ofcX:
21.06
5cdpB-1ofcX:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1ofc ISWI PROTEIN
(Drosophila
melanogaster) 		3 / 3 PHE X 842
ILE X 809
ASP X 826
 None
 0.77A 5cswA-1ofcX:
undetectable		 5cswA-1ofcX:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1ofc ISWI PROTEIN
(Drosophila
melanogaster) 		5 / 8 ILE X 852
LEU X 849
ILE X 855
ILE X 859
ASN X 812
 None
 1.23A 5numA-1ofcX:
undetectable		 5numA-1ofcX:
13.95