SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oft'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1oft HYPOTHETICAL PROTEIN
PA3008
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  69
LEU A  80
VAL A 130
LEU A  62
HIS A  89
 None
 1.25A 1kt7A-1oftA:
0.0		 1kt7A-1oftA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 1oft HYPOTHETICAL PROTEIN
PA3008
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  80
PRO A  83
LEU A 104
ILE A 102
 None
 0.88A 2qd4A-1oftA:
3.9		 2qd4A-1oftA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1oft HYPOTHETICAL PROTEIN
PA3008
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  46
ALA A  45
THR A 128
ARG A 122
GLY A 151
 None
 1.27A 3aodC-1oftA:
undetectable		 3aodC-1oftA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1oft HYPOTHETICAL PROTEIN
PA3008
(Pseudomonas
aeruginosa) 		4 / 4 PRO A  83
LEU A 104
ILE A 102
ARG A  99
 None
 1.12A 3w1wA-1oftA:
4.3		 3w1wA-1oftA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1oft HYPOTHETICAL PROTEIN
PA3008
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  80
PRO A  83
LEU A 104
ILE A 102
 None
 0.94A 4f4dB-1oftA:
4.0		 4f4dB-1oftA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1oft HYPOTHETICAL PROTEIN
PA3008
(Pseudomonas
aeruginosa) 		5 / 7 LEU A  51
LEU A 133
ILE A  65
LEU A  66
ILE A  81
 None
 1.20A 5vkqA-1oftA:
undetectable
5vkqB-1oftA:
undetectable		 5vkqA-1oftA:
6.81
5vkqB-1oftA:
6.81