SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1og0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 145
LEU A 168
LEU A 138
ALA A 141
LEU A 122
 None
 1.15A 1crbA-1og0A:
undetectable		 1crbA-1og0A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 ALA A  84
LEU A  81
LEU A 148
LEU A 153
ILE A  72
 None
 0.98A 2jfaA-1og0A:
undetectable		 2jfaA-1og0A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 ALA A  84
LEU A  81
LEU A 148
LEU A 153
ILE A  72
 None
 0.94A 2qxsA-1og0A:
undetectable		 2qxsA-1og0A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 10 THR A 311
ILE A  62
GLY A 275
GLY A  64
PRO A 197
 None
 1.37A 2y7wB-1og0A:
undetectable		 2y7wB-1og0A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 10 GLU A 158
ILE A 247
GLY A 199
ILE A  72
MET A 314
 None
 1.46A 3adsA-1og0A:
0.0		 3adsA-1og0A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  41
ALA A 141
GLN A 166
ARG A  55
VAL A 146
 None
None
PHE  A1012 (-3.4A)
None
None
 1.14A 3ix9B-1og0A:
undetectable		 3ix9B-1og0A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 156
PRO A  75
GLY A  74
LEU A 171
PHE A 196
 None
 1.45A 3r24A-1og0A:
undetectable		 3r24A-1og0A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 156
SER A 173
PHE A 196
ALA A 169
SER A 164
 None
None
None
PHE  A1012 (-3.2A)
None
 1.27A 3sueD-1og0A:
undetectable		 3sueD-1og0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 9 ARG A 142
ALA A 108
ILE A  72
GLY A 175
LEU A 171
 None
 1.15A 3u7sB-1og0A:
undetectable		 3u7sB-1og0A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 122
LEU A 110
ILE A  78
PHE A 145
SER A 140
 None
 0.82A 4lmnA-1og0A:
undetectable		 4lmnA-1og0A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  70
GLY A 312
LEU A 357
VAL A  73
VAL A 295
 None
 1.44A 4okxA-1og0A:
0.0		 4okxA-1og0A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.11A 4qvpH-1og0A:
undetectable
4qvpI-1og0A:
undetectable		 4qvpH-1og0A:
23.40
4qvpI-1og0A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.11A 4qvpV-1og0A:
undetectable
4qvpW-1og0A:
undetectable		 4qvpV-1og0A:
23.40
4qvpW-1og0A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 11 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.07A 4qvvH-1og0A:
undetectable		 4qvvH-1og0A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 11 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.07A 4qvvV-1og0A:
undetectable		 4qvvV-1og0A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 11 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.06A 4qvyH-1og0A:
undetectable		 4qvyH-1og0A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.07A 4qvyV-1og0A:
undetectable
4qvyW-1og0A:
undetectable		 4qvyV-1og0A:
23.40
4qvyW-1og0A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 11 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.08A 4qw0H-1og0A:
undetectable
4qw0I-1og0A:
undetectable		 4qw0H-1og0A:
23.40
4qw0I-1og0A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 11 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.08A 4qw0V-1og0A:
undetectable
4qw0W-1og0A:
undetectable		 4qw0V-1og0A:
23.40
4qw0W-1og0A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.03A 4qw1H-1og0A:
undetectable
4qw1I-1og0A:
undetectable		 4qw1H-1og0A:
23.40
4qw1I-1og0A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.03A 4qw1V-1og0A:
undetectable
4qw1W-1og0A:
undetectable		 4qw1V-1og0A:
23.40
4qw1W-1og0A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 186
GLY A 193
LEU A 194
ALA A 217
VAL A 198
 None
None
PHE  A1012 (-4.2A)
None
None
 1.09A 4wnwB-1og0A:
0.0		 4wnwB-1og0A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 107
ASP A 279
ARG A 249
ILE A 247
 MN  A 400 ( 4.6A)
None
None
None
 1.30A 5a06A-1og0A:
undetectable		 5a06A-1og0A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.09A 5cz7V-1og0A:
undetectable
5cz7W-1og0A:
undetectable		 5cz7V-1og0A:
23.40
5cz7W-1og0A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 11 GLN A 268
ALA A 179
GLY A 203
ALA A 211
THR A 182
 None
 1.08A 5d0xV-1og0A:
undetectable		 5d0xV-1og0A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 1og0 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 203
ILE A 278
THR A 255
GLY A 254
GLY A 251
 None
 0.86A 5koxA-1og0A:
undetectable		 5koxA-1og0A:
22.09