SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1og6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 7 TYR A  21
MET A  19
ASP A  50
HIS A 128
 None
None
NAP  A1298 (-3.6A)
NAP  A1298 (-4.6A)
 1.22A 1t03A-1og6A:
undetectable		 1t03A-1og6A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 5 GLU A  66
THR A 119
LEU A 117
LEU A  68
 None
 0.94A 1u18B-1og6A:
0.0		 1u18B-1og6A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		3 / 3 MET A 134
ASN A 179
GLN A 198
 None
 0.95A 1xoqB-1og6A:
undetectable		 1xoqB-1og6A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		5 / 11 GLY A  45
ILE A  38
ALA A  67
VAL A  49
ILE A  80
 None
 1.13A 2nnhA-1og6A:
0.0		 2nnhA-1og6A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 5 LEU A 167
LEU A 168
LEU A 126
MET A 134
 None
 1.14A 2oaxF-1og6A:
0.0		 2oaxF-1og6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 7 ALA A  52
TYR A  55
MET A 207
HIS A 128
 None
NAP  A1298 (-4.8A)
None
NAP  A1298 (-4.6A)
 0.96A 2pncA-1og6A:
undetectable		 2pncA-1og6A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		5 / 10 VAL A  49
ILE A  80
LEU A 117
GLY A  65
ALA A  63
 None
 1.08A 2xf3A-1og6A:
undetectable		 2xf3A-1og6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		3 / 3 ARG A 103
ASP A 135
ASP A 141
 None
 0.79A 3jayA-1og6A:
undetectable		 3jayA-1og6A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		3 / 3 ARG A 103
ASP A 135
ASP A 141
 None
 0.85A 3jb2A-1og6A:
0.0		 3jb2A-1og6A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		3 / 3 GLN A 198
THR A 195
LEU A 126
 None
 0.73A 3ondA-1og6A:
undetectable		 3ondA-1og6A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		3 / 3 GLN A 198
THR A 195
LEU A 126
 None
 0.71A 3ondB-1og6A:
undetectable		 3ondB-1og6A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 5 GLY A 213
GLY A 215
ASN A 219
GLU A 182
 NAP  A1298 (-4.0A)
NAP  A1298 (-3.0A)
None
None
 1.18A 4fglC-1og6A:
undetectable		 4fglC-1og6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		5 / 12 ILE A  80
ALA A 110
SER A 113
LEU A 114
LEU A 117
 None
 0.85A 4m11B-1og6A:
0.0		 4m11B-1og6A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		5 / 12 ILE A  80
ALA A 110
SER A 113
LEU A 114
LEU A 117
 None
 0.88A 4o1zA-1og6A:
undetectable		 4o1zA-1og6A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		5 / 12 GLU A 138
ASP A 102
GLY A  85
ALA A  87
LEU A 133
 None
 1.13A 4retC-1og6A:
undetectable		 4retC-1og6A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		5 / 12 GLU A 138
ASP A 102
LEU A 168
GLY A  85
ALA A  87
 None
 1.26A 4retC-1og6A:
undetectable		 4retC-1og6A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 5 LEU A 176
PHE A 155
LEU A 168
PHE A 160
 None
 1.26A 5iy5P-1og6A:
undetectable
5iy5W-1og6A:
0.0		 5iy5P-1og6A:
22.09
5iy5W-1og6A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		5 / 7 ILE A 106
LEU A 172
PHE A 174
THR A 178
ARG A 153
 None
 1.21A 5vc0A-1og6A:
undetectable		 5vc0A-1og6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 5 LEU A 176
PHE A 155
LEU A 168
PHE A 160
 None
 1.22A 5xdxC-1og6A:
undetectable
5xdxJ-1og6A:
0.0		 5xdxC-1og6A:
22.09
5xdxJ-1og6A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 5 LEU A 176
PHE A 155
LEU A 168
PHE A 160
 None
 1.28A 5xdxP-1og6A:
undetectable
5xdxW-1og6A:
0.0		 5xdxP-1og6A:
22.09
5xdxW-1og6A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF
(Escherichia
coli) 		4 / 7 ILE A 261
GLU A  40
HIS A  41
VAL A  46
 None
 1.10A 6j20A-1og6A:
undetectable		 6j20A-1og6A:
20.09