SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ogk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1ogk DEOXYURIDINE
TRIPHOSPHATASE
(Trypanosoma
cruzi) 		5 / 8 PHE A 188
LEU A  18
ALA A  79
LEU A 179
ALA A 183
 None
 1.31A 2vcvF-1ogkA:
undetectable		 2vcvF-1ogkA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1ogk DEOXYURIDINE
TRIPHOSPHATASE
(Trypanosoma
cruzi) 		5 / 12 PHE A 114
LEU A 105
GLU A 141
ARG A 171
SER A  85
 None
 1.10A 3apvA-1ogkA:
undetectable		 3apvA-1ogkA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 1ogk DEOXYURIDINE
TRIPHOSPHATASE
(Trypanosoma
cruzi) 		5 / 12 VAL A  10
THR A 176
ILE A 163
LEU A 190
VAL A 191
 None
 1.28A 3sp9B-1ogkA:
undetectable		 3sp9B-1ogkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 1ogk DEOXYURIDINE
TRIPHOSPHATASE
(Trypanosoma
cruzi) 		3 / 3 ASP A  70
ASP A  80
ASN A 201
 None
 0.81A 6gngB-1ogkA:
undetectable		 6gngB-1ogkA:
19.41