SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ohf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 12 ALA A 163
ARG A 216
LEU A 152
ILE A 154
THR A 162
None
1.25A 1d1gA-1ohfA:
undetectable
1d1gA-1ohfA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 12 ASN A 188
LEU A 190
GLY A 493
MET A 159
ILE A 184
None
1.37A 1p93A-1ohfA:
undetectable
1p93A-1ohfA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 12 ASN A 188
LEU A 190
GLY A 493
THR A 478
ILE A 184
None
1.40A 1p93A-1ohfA:
undetectable
1p93A-1ohfA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 12 LEU A 187
ASN A 188
LEU A 190
MET A 159
THR A 478
None
1.27A 2aa6A-1ohfA:
undetectable
2aa6A-1ohfA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 ALA A 163
THR A 522
PHE A 165
None
0.70A 2c6nB-1ohfA:
0.0
2c6nB-1ohfA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 6 SER A 476
SER A 422
ARG A 495
GLU A 423
None
1.47A 2c8aC-1ohfA:
undetectable
2c8aC-1ohfA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 THR A 102
PRO A  98
TYR A 523
None
0.97A 2dxrA-1ohfA:
0.0
2dxrA-1ohfA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 PHE A 371
PHE A 286
PHE A 408
None
0.81A 2od9A-1ohfA:
undetectable
2od9A-1ohfA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 PHE A 371
PHE A 286
PHE A 408
None
0.81A 2qqgA-1ohfA:
undetectable
2qqgA-1ohfA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 8 SER A 303
GLN A 326
GLY A 492
GLY A 490
None
0.74A 2vinA-1ohfA:
undetectable
2vinA-1ohfA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 HIS A 284
MET A 349
MET A 304
None
1.11A 2vj1A-1ohfA:
0.0
2vj1A-1ohfA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 7 ARG A 128
GLU A 129
ALA A 125
PRO A 220
None
1.08A 2zgwA-1ohfA:
undetectable
2zgwA-1ohfA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 9 GLY A 331
PRO A 315
THR A 336
GLY A 337
ARG A 290
None
1.33A 3bjwG-1ohfA:
0.0
3bjwG-1ohfA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 9 ARG A 194
ILE A 155
ILE A 475
VAL A 217
ILE A 215
None
1.15A 3d1yB-1ohfA:
undetectable
3d1yB-1ohfA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 9 ASN A 189
ALA A 191
GLN A 324
ALA A 302
SER A 303
None
1.27A 3kp6B-1ohfA:
undetectable
3kp6B-1ohfA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 11 VAL A 446
GLY A 262
GLY A 263
TYR A 265
ASN A 438
None
1.47A 3owxA-1ohfA:
undetectable
3owxB-1ohfA:
undetectable
3owxA-1ohfA:
16.15
3owxB-1ohfA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 LEU A 393
ARG A 409
ASN A 364
None
0.62A 3qxvD-1ohfA:
2.3
3qxvD-1ohfA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 6 PHE A 408
TYR A 341
VAL A 338
PHE A 325
None
1.18A 4a97E-1ohfA:
1.2
4a97E-1ohfA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 7 ASP A 195
GLY A 292
THR A 400
SER A 192
None
0.99A 4ac9C-1ohfA:
undetectable
4ac9C-1ohfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 5 THR A 355
THR A 356
ASP A 353
TYR A 351
None
1.45A 4oltA-1ohfA:
0.0
4oltA-1ohfA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 5 THR A 355
THR A 356
ASP A 353
TYR A 351
None
1.44A 4oltB-1ohfA:
0.0
4oltB-1ohfA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 PRO A 158
MET A 159
TYR A 157
None
1.08A 4qa0A-1ohfA:
undetectable
4qa0A-1ohfA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 PRO A 158
MET A 159
TYR A 157
None
1.04A 4qa2B-1ohfA:
undetectable
4qa2B-1ohfA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 5 THR A 355
THR A 356
ASP A 353
TYR A 351
None
1.44A 4qwpA-1ohfA:
undetectable
4qwpA-1ohfA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 ASP A  97
SER A 244
TYR A 453
None
0.87A 5glmA-1ohfA:
0.0
5glmA-1ohfA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 12 LEU A 454
ALA A 505
PRO A 427
ILE A 154
LEU A 187
None
0.96A 5ljeA-1ohfA:
1.9
5ljeA-1ohfA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 10 THR A 385
ILE A 384
LEU A 299
PHE A 371
GLY A 337
None
0.99A 5mxbA-1ohfA:
undetectable
5mxbA-1ohfA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
5 / 12 ASN A 188
LEU A 190
GLY A 493
GLY A 492
MET A 159
None
0.93A 5uc1B-1ohfA:
undetectable
5uc1B-1ohfA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 GLY A 432
THR A 430
GLU A 174
None
0.49A 6b58A-1ohfA:
undetectable
6b58A-1ohfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
3 / 3 PHE A 491
ARG A 495
GLN A 324
None
1.17A 6g1pB-1ohfA:
0.0
6g1pB-1ohfA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 6 GLY A 543
LEU A 544
VAL A 235
PHE A 160
None
0.83A 6h7lA-1ohfA:
undetectable
6h7lA-1ohfA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis
omega
virus)
4 / 6 GLY A 543
LEU A 544
VAL A 235
PHE A 160
None
0.84A 6h7lB-1ohfA:
undetectable
6h7lB-1ohfA:
10.23