SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ohq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1ohq IMMUNOGLOBULIN
(Homo
sapiens) 		4 / 8 MET A  34
PHE A 109
ALA A  24
ILE A  29
 None
 1.17A 1gm7A-1ohqA:
undetectable
1gm7B-1ohqA:
undetectable		 1gm7A-1ohqA:
21.00
1gm7B-1ohqA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 1ohq IMMUNOGLOBULIN
(Homo
sapiens) 		5 / 9 ARG A  38
ALA A  88
VAL A 118
SER A 119
ASP A  90
 None
 1.41A 6c2mA-1ohqA:
undetectable		 6c2mA-1ohqA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 1ohq IMMUNOGLOBULIN
(Homo
sapiens) 		5 / 9 ARG A  38
ALA A  88
VAL A 118
SER A 119
ASP A  90
 None
 1.38A 6c2mB-1ohqA:
undetectable		 6c2mB-1ohqA:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 1ohq IMMUNOGLOBULIN
(Homo
sapiens) 		3 / 3 TYR A  60
GLY A  66
THR A  69
 None
 0.17A 6cjkB-1ohqA:
18.4		 6cjkB-1ohqA:
58.68