SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oi0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)
1oi0 HYPOTHETICAL PROTEIN
AF2198

(Archaeoglobus
fulgidus)
5 / 9 GLY A   9
LEU A  10
LEU A  11
ARG A   8
ILE A   6
None
1.49A 3nbqD-1oi0A:
undetectable
3nbqD-1oi0A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
1oi0 HYPOTHETICAL PROTEIN
AF2198

(Archaeoglobus
fulgidus)
5 / 12 ALA A  17
TRP A 106
LEU A  10
GLY A   9
MET A  37
None
1.25A 3nrrA-1oi0A:
0.0
3nrrA-1oi0A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)
1oi0 HYPOTHETICAL PROTEIN
AF2198

(Archaeoglobus
fulgidus)
5 / 12 GLY A  67
GLY A  91
ILE A  14
THR A  13
LEU A  10
None
1.28A 4n48A-1oi0A:
undetectable
4n48A-1oi0A:
16.44