SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oi1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		3 / 3 TYR A 215
ARG A 222
GLN A  54
 None
 0.96A 1tw4A-1oi1A:
undetectable		 1tw4A-1oi1A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 200
TYR A 219
LYS A 166
 None
 1.14A 2othA-1oi1A:
undetectable		 2othA-1oi1A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 178
VAL A 174
GLY A 175
THR A 205
ILE A 204
 None
 0.95A 3bf1A-1oi1A:
undetectable
3bf1B-1oi1A:
undetectable		 3bf1A-1oi1A:
21.76
3bf1B-1oi1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		5 / 9 ASP A 214
GLY A 211
ASP A 182
GLY A 241
THR A 193
 None
 1.07A 3gguB-1oi1A:
undetectable		 3gguB-1oi1A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		4 / 7 LEU A 109
ILE A 189
THR A 233
GLY A  90
 None
 0.96A 4eq4A-1oi1A:
undetectable		 4eq4A-1oi1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		4 / 7 LEU A 109
ILE A 189
THR A 233
GLY A  90
 None
 0.95A 4eqlB-1oi1A:
undetectable		 4eqlB-1oi1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 109
ILE A 189
THR A 233
GLY A  90
 None
 0.90A 4l39A-1oi1A:
undetectable		 4l39A-1oi1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		4 / 7 LEU A 109
ILE A 189
THR A 233
GLY A  90
 None
 0.89A 4l39B-1oi1A:
undetectable		 4l39B-1oi1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		6 / 10 ALA A  47
ILE A 194
VAL A 202
ALA A 180
ALA A 192
ILE A 204
 None
 1.44A 4lbgA-1oi1A:
undetectable		 4lbgA-1oi1A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		6 / 9 ALA A  47
ILE A 194
VAL A 202
ALA A 180
ALA A 192
ILE A 204
 None
 1.37A 4lbgB-1oi1A:
undetectable		 4lbgB-1oi1A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		5 / 10 GLU A  37
HIS A  34
ALA A 227
GLY A 228
ARG A 231
 None
 1.20A 6bniA-1oi1A:
undetectable		 6bniA-1oi1A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 1oi1 SCML2 PROTEIN
(Homo
sapiens) 		5 / 10 GLU A  37
HIS A  34
ALA A 227
GLY A 228
ARG A 231
 None
 1.23A 6bniB-1oi1A:
undetectable		 6bniB-1oi1A:
13.68