SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oi4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		5 / 11 ASP A  44
PHE A  39
VAL A  28
ILE A  26
LEU A  91
 None
 1.02A 2dg9A-1oi4A:
undetectable		 2dg9A-1oi4A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		5 / 12 LEU A  92
LEU A 130
VAL A 136
LEU A 171
THR A 173
 None
 1.39A 2q7kA-1oi4A:
undetectable		 2q7kA-1oi4A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		5 / 11 ASP A  44
PHE A  39
VAL A  28
ILE A  26
LYS A  48
 None
 1.35A 3o5rA-1oi4A:
undetectable		 3o5rA-1oi4A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		4 / 5 PHE A  39
ASP A  36
PHE A  34
VAL A  73
 None
 1.06A 5a1rA-1oi4A:
undetectable		 5a1rA-1oi4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		4 / 6 GLU A  57
PHE A 107
GLU A  81
VAL A  82
 None
 1.24A 5h4dA-1oi4A:
5.6		 5h4dA-1oi4A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		5 / 9 VAL A  53
HIS A  10
ASP A  76
ILE A  75
VAL A  64
 None
 1.43A 5v0iA-1oi4A:
undetectable		 5v0iA-1oi4A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		5 / 9 VAL A  53
HIS A  10
ASP A  76
ILE A  75
VAL A  64
 None
 1.42A 5v0iB-1oi4A:
undetectable		 5v0iB-1oi4A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		4 / 8 THR A 176
PHE A 159
HIS A 126
ILE A 148
 None
 1.03A 5vkqB-1oi4A:
undetectable
5vkqC-1oi4A:
undetectable		 5vkqB-1oi4A:
7.39
5vkqC-1oi4A:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		5 / 10 GLU A  38
GLY A  94
GLY A  95
ILE A 124
PRO A 128
 None
 0.35A 6e5zA-1oi4A:
25.1		 6e5zA-1oi4A:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		4 / 7 GLY A  94
PHE A  34
VAL A  28
SER A  37
 None
 0.99A 6hu9S-1oi4A:
0.0
6hu9q-1oi4A:
0.0		 6hu9S-1oi4A:
19.08
6hu9q-1oi4A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		5 / 11 HIS A   9
ASP A  76
LEU A  29
PHE A  39
ALA A  43
 None
 1.16A 6ieyA-1oi4A:
undetectable
6ieyB-1oi4A:
3.3		 6ieyA-1oi4A:
21.29
6ieyB-1oi4A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1oi4 HYPOTHETICAL PROTEIN
YHBO
(Escherichia
coli) 		4 / 8 ASP A 178
HIS A 126
GLU A  38
GLU A  70
 None
 1.31A 6mn4C-1oi4A:
undetectable		 6mn4C-1oi4A:
20.30