SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 8 GLY A 241
THR A 181
GLY A 101
ASP A 141
 None
CDM  A1284 (-3.6A)
ANP  A1285 (-2.9A)
CDM  A1284 (-2.9A)
 0.78A 1aegA-1oj4A:
undetectable		 1aegA-1oj4A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 5 GLY A 241
LEU A 237
THR A 238
VAL A 222
 None
 0.98A 1ekjF-1oj4A:
undetectable
1ekjG-1oj4A:
undetectable		 1ekjF-1oj4A:
20.89
1ekjG-1oj4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 8 THR A 238
GLY A 239
GLY A 106
LEU A 104
GLY A 101
 None
CDM  A1284 ( 4.2A)
ANP  A1285 (-4.1A)
None
ANP  A1285 (-2.9A)
 1.40A 1jhqA-1oj4A:
undetectable		 1jhqA-1oj4A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 8 THR A 238
GLY A 239
GLY A 106
LEU A 104
GLY A 101
 None
CDM  A1284 ( 4.2A)
ANP  A1285 (-4.1A)
None
ANP  A1285 (-2.9A)
 1.37A 1jhvA-1oj4A:
undetectable		 1jhvA-1oj4A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 7 LYS A 271
LEU A  35
PHE A  34
PHE A 245
 None
 0.90A 1v55P-1oj4A:
undetectable
1v55W-1oj4A:
undetectable		 1v55P-1oj4A:
23.79
1v55W-1oj4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 8 GLY A 101
GLY A 102
GLY A 103
LEU A 237
ILE A 184
 ANP  A1285 (-2.9A)
ANP  A1285 (-4.0A)
ANP  A1285 (-3.0A)
None
None
 1.02A 1yajC-1oj4A:
undetectable		 1yajC-1oj4A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 7 LYS A 271
LEU A  35
PHE A  34
PHE A 245
 None
 0.89A 2dysC-1oj4A:
0.1
2dysJ-1oj4A:
undetectable		 2dysC-1oj4A:
23.79
2dysJ-1oj4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 7 LYS A 271
LEU A  35
PHE A  34
PHE A 245
 None
 0.96A 2eijC-1oj4A:
undetectable
2eijJ-1oj4A:
undetectable		 2eijC-1oj4A:
23.79
2eijJ-1oj4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 7 LYS A 271
LEU A  35
PHE A  34
PHE A 245
 None
 0.91A 2eijP-1oj4A:
undetectable
2eijW-1oj4A:
undetectable		 2eijP-1oj4A:
23.79
2eijW-1oj4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 7 LYS A 271
LEU A  35
PHE A  34
PHE A 245
 None
 0.86A 2zxwC-1oj4A:
undetectable
2zxwJ-1oj4A:
undetectable		 2zxwC-1oj4A:
23.79
2zxwJ-1oj4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 8 LYS A 271
LEU A  35
PHE A  34
PHE A 245
 None
 0.94A 3asoC-1oj4A:
undetectable
3asoJ-1oj4A:
undetectable		 3asoC-1oj4A:
23.79
3asoJ-1oj4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 12 GLY A 105
GLY A 107
SER A 178
ILE A 179
GLY A 103
 ANP  A1285 (-2.6A)
ANP  A1285 (-3.2A)
None
None
ANP  A1285 (-3.0A)
 1.01A 3axzA-1oj4A:
0.0		 3axzA-1oj4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		6 / 12 LEU A 237
GLY A 103
GLY A 102
LEU A  98
PRO A  99
SER A 109
 None
ANP  A1285 (-3.0A)
ANP  A1285 (-4.0A)
None
None
None
 1.33A 3i5uB-1oj4A:
undetectable		 3i5uB-1oj4A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 5 ASN A 110
ASP A 141
THR A 240
SER A   7
 ANP  A1285 (-3.7A)
CDM  A1284 (-2.9A)
CDM  A1284 ( 4.8A)
None
 1.46A 3p2kC-1oj4A:
undetectable		 3p2kC-1oj4A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 12 GLY A 241
GLY A 239
SER A 178
GLU A 212
ALA A 215
 None
CDM  A1284 ( 4.2A)
None
None
None
 1.22A 3sxjA-1oj4A:
undetectable		 3sxjA-1oj4A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 12 GLY A 241
GLY A 239
SER A 178
GLU A 212
ALA A 215
 None
CDM  A1284 ( 4.2A)
None
None
None
 1.23A 3sxjB-1oj4A:
undetectable		 3sxjB-1oj4A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		3 / 3 ARG A 218
PRO A 180
PHE A 219
 None
 0.92A 3thrC-1oj4A:
undetectable		 3thrC-1oj4A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 6 LEU A 230
GLU A 247
VAL A 172
ALA A 173
 None
 1.18A 4nkvC-1oj4A:
0.0		 4nkvC-1oj4A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		3 / 3 ALA A 153
GLN A  33
GLY A 272
 None
 0.48A 4odoC-1oj4A:
undetectable		 4odoC-1oj4A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 12 GLY A 105
GLY A 107
SER A 178
ILE A 179
GLY A 103
 ANP  A1285 (-2.6A)
ANP  A1285 (-3.2A)
None
None
ANP  A1285 (-3.0A)
 1.02A 4yvgA-1oj4A:
undetectable		 4yvgA-1oj4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 4 LEU A  66
ILE A  67
GLY A 107
ILE A  94
 ANP  A1285 (-4.0A)
ANP  A1285 ( 4.9A)
ANP  A1285 (-3.2A)
None
 0.81A 5dzk3-1oj4A:
undetectable
5dzkm-1oj4A:
undetectable		 5dzk3-1oj4A:
0.71
5dzkm-1oj4A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 5 ILE A  67
GLY A 107
ILE A  94
LEU A  66
 ANP  A1285 ( 4.9A)
ANP  A1285 (-3.2A)
None
ANP  A1285 (-4.0A)
 0.80A 5dzkB-1oj4A:
undetectable
5dzkI-1oj4A:
undetectable
5dzkW-1oj4A:
undetectable		 5dzkB-1oj4A:
22.03
5dzkI-1oj4A:
21.23
5dzkW-1oj4A:
0.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 5 ILE A  67
GLY A 107
ILE A  94
LEU A  66
 ANP  A1285 ( 4.9A)
ANP  A1285 (-3.2A)
None
ANP  A1285 (-4.0A)
 0.81A 5dzki-1oj4A:
undetectable
5dzkj-1oj4A:
undetectable
5dzkx-1oj4A:
undetectable		 5dzki-1oj4A:
21.23
5dzkj-1oj4A:
21.23
5dzkx-1oj4A:
0.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 5 ILE A  67
GLY A 107
ILE A  94
LEU A  66
 ANP  A1285 ( 4.9A)
ANP  A1285 (-3.2A)
None
ANP  A1285 (-4.0A)
 0.80A 5dzkd-1oj4A:
undetectable
5dzkk-1oj4A:
undetectable
5dzky-1oj4A:
undetectable		 5dzkd-1oj4A:
22.03
5dzkk-1oj4A:
21.23
5dzky-1oj4A:
0.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 4 ILE A  67
GLY A 107
ILE A  94
LEU A  66
 ANP  A1285 ( 4.9A)
ANP  A1285 (-3.2A)
None
ANP  A1285 (-4.0A)
 0.72A 5dzkl-1oj4A:
undetectable
5dzkz-1oj4A:
undetectable		 5dzkl-1oj4A:
21.23
5dzkz-1oj4A:
0.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 6 LYS A 271
LEU A  35
PHE A  34
PHE A 245
 None
 0.92A 5w97C-1oj4A:
0.0
5w97J-1oj4A:
0.0		 5w97C-1oj4A:
23.79
5w97J-1oj4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 12 GLY A 241
TYR A  37
GLY A 103
GLY A 102
PRO A  99
 None
None
ANP  A1285 (-3.0A)
ANP  A1285 (-4.0A)
None
 0.93A 5wyqB-1oj4A:
undetectable		 5wyqB-1oj4A:
26.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 7 LYS A 271
LEU A  35
PHE A  34
PHE A 245
 None
 0.93A 5x1fP-1oj4A:
undetectable
5x1fW-1oj4A:
undetectable		 5x1fP-1oj4A:
23.79
5x1fW-1oj4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 12 ILE A  41
THR A  55
VAL A  57
LEU A  74
ALA A  70
 None
 1.14A 6djzA-1oj4A:
undetectable		 6djzA-1oj4A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 5 THR A 240
CYH A 243
THR A 238
GLY A 239
 CDM  A1284 ( 4.8A)
None
None
CDM  A1284 ( 4.2A)
 1.27A 6gtqA-1oj4A:
1.9		 6gtqA-1oj4A:
21.33